Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 145078..145985 Replicon plasmid pPaFU01
Accession NZ_AP019754
Organism Pantoea ananatis strain FU-01

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag PAFU01_RS22165 Protein ID WP_022622882.1
Coordinates 145078..145545 (-) Length 156 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A8A4JZ23
Locus tag PAFU01_RS22170 Protein ID WP_014598335.1
Coordinates 145542..145985 (-) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PAFU01_RS22145 (PAFU01_43300) 140464..140697 - 234 WP_013027857.1 DUF333 domain-containing protein -
PAFU01_RS22150 (PAFU01_43310) 140785..141357 + 573 WP_014598338.1 NADPH-dependent FMN reductase -
PAFU01_RS22155 (PAFU01_43320) 141419..142354 - 936 WP_013027859.1 flagellin -
PAFU01_RS22160 (PAFU01_43330) 143038..144432 - 1395 WP_014333136.1 flagellar filament capping protein FliD -
PAFU01_RS22165 (PAFU01_43340) 145078..145545 - 468 WP_022622882.1 RES family NAD+ phosphorylase Toxin
PAFU01_RS22170 (PAFU01_43350) 145542..145985 - 444 WP_014598335.1 DUF2384 domain-containing protein Antitoxin
PAFU01_RS22175 (PAFU01_43360) 146372..146596 + 225 WP_013027863.1 KTSC domain-containing protein -
PAFU01_RS22180 (PAFU01_43370) 146750..147445 + 696 WP_064374342.1 hypothetical protein -
PAFU01_RS22185 (PAFU01_43380) 147520..148209 - 690 WP_019105825.1 HTH-type transcriptional regulator RutR -
PAFU01_RS22190 (PAFU01_43390) 148608..149699 + 1092 WP_019105824.1 pyrimidine utilization protein A -
PAFU01_RS22195 (PAFU01_43400) 149696..150448 + 753 WP_265166125.1 pyrimidine utilization protein B -
PAFU01_RS22200 (PAFU01_43410) 150474..150860 + 387 WP_013027868.1 pyrimidine utilization protein C -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - fliC / fliC 1..281268 281268


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(2-145)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(31-89)


Sequences

Toxin        


Download         Length: 156 a.a.        Molecular weight: 17179.64 Da        Isoelectric Point: 5.1570

>T32999 WP_022622882.1 NZ_AP019754:c145545-145078 [Pantoea ananatis]
MKLYRMTKTRYLGSAWSGFGAREGGGRWNSVGVSMVYASETASLTMLETLIHLQSASVLDFFTLMSIDVPDRLIEWIDIK
QLPDDWAAPEAPAALRLFGDAWIQSGGSVALRVPSALSPVESNYLLNPEHPEFSAIVRQAVNIPFLFDARFSRQA

Download         Length: 468 bp

>T32999 NZ_AP019754:c145545-145078 [Pantoea ananatis]
TTGAAGCTCTATCGCATGACCAAAACGCGCTATCTGGGGTCGGCCTGGAGCGGTTTTGGTGCCCGTGAAGGCGGCGGACG
CTGGAACAGCGTCGGCGTATCGATGGTCTACGCTTCTGAAACTGCTTCCCTCACCATGCTGGAGACGCTTATCCATCTGC
AAAGCGCCAGCGTACTGGACTTTTTTACCCTCATGAGCATTGACGTTCCCGACAGGCTGATTGAATGGATTGATATCAAG
CAACTGCCTGACGACTGGGCCGCACCGGAAGCGCCTGCAGCGCTGCGTTTATTTGGTGATGCCTGGATACAAAGCGGGGG
ATCGGTCGCACTGCGCGTGCCCAGTGCCCTTTCGCCCGTGGAATCGAATTATCTTCTCAATCCGGAGCATCCTGAATTCA
GTGCGATCGTCAGACAGGCGGTAAATATCCCCTTCCTTTTTGATGCACGCTTTTCCCGACAGGCATAA

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16375.69 Da        Isoelectric Point: 7.0208

>AT32999 WP_014598335.1 NZ_AP019754:c145985-145542 [Pantoea ananatis]
MKQFTLPVSAAEPDRLWQFAGLSSADGVMLMDQIDDGLDGTVASRIVTWAQISQAELRRMTGIAGSTFTRGVKSRFTAEQ
SERLVRFIRVMDRAVELFEGDKEKARQWLNEPARALGNKKPADLVASETGAYEVLKLITRLEHGVYS

Download         Length: 444 bp

>AT32999 NZ_AP019754:c145985-145542 [Pantoea ananatis]
ATGAAACAGTTCACTTTACCCGTATCCGCTGCAGAACCGGATCGTCTATGGCAATTTGCTGGCCTGAGCAGTGCTGACGG
CGTGATGCTGATGGATCAAATCGATGATGGTCTGGACGGCACGGTAGCCAGTCGCATTGTCACCTGGGCGCAAATCTCTC
AGGCAGAACTGCGCCGTATGACCGGCATTGCGGGCTCAACCTTCACCCGCGGCGTTAAAAGCCGCTTTACTGCGGAGCAG
AGCGAACGGCTGGTGCGTTTTATTCGCGTGATGGATCGTGCGGTTGAGCTGTTTGAGGGCGATAAAGAAAAGGCACGGCA
GTGGCTCAATGAGCCTGCGCGCGCCTTAGGCAATAAAAAACCGGCTGATCTGGTCGCGTCAGAAACCGGGGCTTATGAAG
TGCTGAAACTCATTACCCGGCTTGAACACGGTGTGTATTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References