Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-MqsA
Location 1970618..1971353 Replicon chromosome
Accession NZ_AP019753
Organism Pantoea ananatis strain FU-01

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PAFU01_RS09210 Protein ID WP_116197574.1
Coordinates 1970618..1971010 (+) Length 131 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PAFU01_RS09215 Protein ID WP_014605595.1
Coordinates 1971000..1971353 (+) Length 118 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PAFU01_RS09195 (PAFU01_17970) 1965919..1967091 - 1173 WP_013026120.1 FMNH2-dependent alkanesulfonate monooxygenase -
PAFU01_RS09200 (PAFU01_17980) 1967365..1969251 + 1887 WP_116197572.1 aliphatic sulfonate ABC transporter substrate-binding protein -
PAFU01_RS09205 (PAFU01_17990) 1969346..1970293 + 948 WP_116197573.1 sulfonate ABC transporter substrate-binding protein -
PAFU01_RS09210 (PAFU01_18000) 1970618..1971010 + 393 WP_116197574.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PAFU01_RS09215 (PAFU01_18010) 1971000..1971353 + 354 WP_014605595.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
PAFU01_RS09220 (PAFU01_18020) 1972345..1973073 - 729 WP_116197575.1 hypothetical protein -
PAFU01_RS09225 (PAFU01_18030) 1973545..1973991 + 447 WP_116197576.1 hypothetical protein -
PAFU01_RS09245 (PAFU01_18040) 1974874..1975413 - 540 WP_024472094.1 peptide-methionine (S)-S-oxide reductase MsrA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(8-125)

Antitoxin

Cro/C1-type helix-turn-helix domain

(56-99)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14790.12 Da        Isoelectric Point: 9.8572

>T32988 WP_116197574.1 NZ_AP019753:1970618-1971010 [Pantoea ananatis]
MGFTLYVHNVLTKCLKKTRLTDSVLCYAAVDVITGVFEADLGGGVIKKRLALHQGKRGGARTIIFFRQGTNLVYYDGWGK
NLSRKYAREIDEDQLDTYRDVARMFFRANSEVMSLLVRSGMVREVKCNEN

Download         Length: 393 bp

>T32988 NZ_AP019753:1970618-1971010 [Pantoea ananatis]
ATGGGTTTTACGCTTTATGTTCATAACGTTTTGACAAAGTGTTTAAAAAAAACGCGTCTGACAGACAGCGTCCTGTGTTA
CGCAGCAGTTGACGTTATTACTGGCGTGTTTGAGGCTGACTTAGGCGGTGGCGTTATTAAAAAGCGCCTTGCTCTTCACC
AAGGCAAGCGTGGCGGCGCGCGAACGATCATCTTCTTCAGACAAGGCACCAACCTGGTTTATTACGATGGATGGGGCAAA
AACTTGTCGAGAAAATACGCCAGGGAAATCGATGAAGATCAGCTGGATACCTACAGGGATGTGGCAAGAATGTTTTTCCG
TGCAAATAGTGAAGTGATGAGCCTGCTCGTCAGAAGCGGAATGGTCAGAGAGGTTAAATGTAATGAAAACTGA

Antitoxin


Download         Length: 118 a.a.        Molecular weight: 13096.14 Da        Isoelectric Point: 7.2076

>AT32988 WP_014605595.1 NZ_AP019753:1971000-1971353 [Pantoea ananatis]
MKTEPAELSELLEDAKAFHALGLATDEEVESIAKRAKNRELRARIASVKPMTATEIKDVRMRWGMSQSLVALSFGMTVDS
VSKWERGEITPSPPVMRMLQLLRDNGPELFTSKHQGI

Download         Length: 354 bp

>AT32988 NZ_AP019753:1971000-1971353 [Pantoea ananatis]
ATGAAAACTGAACCCGCCGAATTGAGTGAACTACTTGAAGATGCGAAAGCGTTTCACGCGTTAGGACTGGCAACAGATGA
AGAAGTGGAGTCCATAGCAAAGCGCGCAAAAAATCGTGAACTCCGTGCCCGTATTGCATCAGTAAAGCCCATGACAGCAA
CTGAAATCAAAGACGTGCGCATGCGTTGGGGAATGTCGCAATCGCTTGTGGCGCTCTCATTTGGCATGACGGTCGATAGT
GTATCGAAATGGGAGCGAGGTGAAATCACACCGAGCCCACCGGTGATGCGGATGCTGCAACTCCTTCGCGATAACGGCCC
TGAACTCTTTACCTCTAAGCATCAAGGTATCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References