Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 4084046..4084707 Replicon chromosome
Accession NZ_AP019700
Organism Stella humosa strain ATCC 43930

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag STVA_RS19165 Protein ID WP_123693118.1
Coordinates 4084046..4084408 (+) Length 121 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag STVA_RS19170 Protein ID WP_197735683.1
Coordinates 4084414..4084707 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
STVA_RS19140 4079337..4079792 + 456 WP_197735930.1 YaiI/YqxD family protein -
STVA_RS19145 4079800..4080495 - 696 WP_123693126.1 VIT family protein -
STVA_RS19150 4080549..4081601 - 1053 WP_123693124.1 hydroxyacid dehydrogenase -
STVA_RS19155 4081625..4082872 - 1248 WP_123693122.1 TIGR03862 family flavoprotein -
STVA_RS19160 4082869..4083834 - 966 WP_123693120.1 S1C family serine protease -
STVA_RS19165 4084046..4084408 + 363 WP_123693118.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
STVA_RS19170 4084414..4084707 + 294 WP_197735683.1 helix-turn-helix domain-containing protein Antitoxin
STVA_RS19175 4084789..4085253 + 465 WP_123693115.1 nuclear transport factor 2 family protein -
STVA_RS19180 4085250..4085714 + 465 WP_123693114.1 nuclear transport factor 2 family protein -
STVA_RS19185 4085707..4086408 - 702 WP_123693113.1 GntR family transcriptional regulator -
STVA_RS19190 4086405..4089329 - 2925 WP_123693881.1 FAD-binding oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-106)

Antitoxin

HigA2-like, helix-turn-helix domain

(6-84)


Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13321.13 Da        Isoelectric Point: 8.4871

>T32914 WP_123693118.1 NZ_AP019700:4084046-4084408 [Stella humosa]
MTRPLGWIGSAREDLLAFPDGVIREIGHALFVAQTGGKHGSAKPLQGFGGAGVLEIVEDHDGDTYRAVYTVRFAEIIYVL
HAFQKKSKSGTATPLREIERIKARLKQAQQEYAEWKQDNP

Download         Length: 363 bp

>T32914 NZ_AP019700:4084046-4084408 [Stella humosa]
ATGACGCGCCCGCTCGGCTGGATCGGCAGTGCCCGCGAGGACCTTCTGGCTTTTCCGGATGGTGTCATCCGCGAGATCGG
CCACGCGTTGTTCGTCGCGCAGACGGGTGGAAAGCATGGCAGCGCCAAGCCGTTGCAGGGATTCGGCGGTGCGGGCGTAC
TCGAAATCGTCGAAGACCACGACGGCGATACCTACCGCGCCGTCTATACCGTCCGTTTTGCCGAGATCATCTATGTGCTG
CACGCCTTCCAGAAAAAATCCAAGAGCGGCACAGCGACGCCGCTGCGCGAGATCGAGCGCATCAAGGCACGTCTGAAGCA
GGCACAGCAGGAGTACGCCGAATGGAAGCAAGACAACCCGTAG

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10463.06 Da        Isoelectric Point: 8.9338

>AT32914 WP_197735683.1 NZ_AP019700:4084414-4084707 [Stella humosa]
VAESAFHALGLPDADDLVLRAQLLRRIADVVREQDLTQAQAGALIGMDQPRVSALLNGKITKFSTDRLLRALSDLGQDVE
LRITPAGRPKGRLHVAA

Download         Length: 294 bp

>AT32914 NZ_AP019700:4084414-4084707 [Stella humosa]
GTGGCCGAGAGCGCCTTTCATGCGCTGGGCCTGCCGGATGCCGACGACCTCGTGCTCCGTGCCCAACTGCTGCGGCGGAT
CGCCGATGTGGTTCGCGAGCAGGACCTGACCCAGGCCCAGGCTGGCGCGCTGATTGGCATGGACCAGCCACGCGTCTCGG
CCTTGCTGAACGGCAAGATCACCAAGTTCTCGACCGACCGGTTGCTCCGCGCATTGAGCGACCTTGGCCAGGATGTCGAA
CTGCGGATTACCCCGGCCGGGCGCCCGAAGGGTCGGCTGCATGTAGCGGCATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References