Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 3697702..3698375 Replicon chromosome
Accession NZ_AP019700
Organism Stella humosa strain ATCC 43930

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag STVA_RS17330 Protein ID WP_123693768.1
Coordinates 3697702..3698124 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag STVA_RS17335 Protein ID WP_123693766.1
Coordinates 3698121..3698375 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
STVA_RS17305 3693166..3694212 + 1047 WP_123693777.1 cyclase family protein -
STVA_RS17310 3694289..3694759 + 471 WP_123693775.1 cupin domain-containing protein -
STVA_RS17315 3694763..3695674 - 912 WP_123693773.1 aminotransferase class IV -
STVA_RS17320 3695678..3696421 - 744 WP_197735661.1 hypothetical protein -
STVA_RS17325 3696577..3697686 + 1110 WP_123693769.1 Ldh family oxidoreductase -
STVA_RS17330 3697702..3698124 - 423 WP_123693768.1 type II toxin-antitoxin system VapC family toxin Toxin
STVA_RS17335 3698121..3698375 - 255 WP_123693766.1 plasmid stabilization protein Antitoxin
STVA_RS17340 3698497..3699642 + 1146 WP_123693764.1 alpha-hydroxy-acid oxidizing protein -
STVA_RS17345 3699659..3700069 - 411 WP_123693762.1 type II toxin-antitoxin system MqsA family antitoxin -
STVA_RS17350 3700062..3700382 - 321 WP_123693760.1 type II toxin-antitoxin system MqsR family toxin -
STVA_RS17355 3700432..3701418 - 987 WP_123693758.1 2-dehydropantoate 2-reductase -
STVA_RS17360 3701478..3702173 - 696 WP_123693756.1 urea ABC transporter ATP-binding subunit UrtE -
STVA_RS17365 3702176..3702931 - 756 WP_123693754.1 urea ABC transporter ATP-binding protein UrtD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 14717.11 Da        Isoelectric Point: 5.1340

>T32913 WP_123693768.1 NZ_AP019700:c3698124-3697702 [Stella humosa]
MILLDTHVICEAMKPEPDPAVREWLDDQAAETLYLSSVTIAELLFGIGALPMGKRKAKLAAALDGVLEIFVGRILPFDMR
AARLYADLAVRARAAGRGFPTPDGYIAAIAAAHGLAVASRDSSAFAAAGLSVIDPWTPAA

Download         Length: 423 bp

>T32913 NZ_AP019700:c3698124-3697702 [Stella humosa]
ATGATCCTGCTCGACACCCATGTCATCTGCGAGGCCATGAAGCCTGAGCCGGATCCAGCGGTCCGCGAATGGCTCGACGA
TCAGGCGGCGGAGACATTGTATTTATCCAGCGTCACCATCGCCGAGTTGCTGTTTGGCATCGGCGCGCTACCGATGGGCA
AGCGCAAGGCCAAGCTCGCGGCTGCGCTCGACGGTGTGTTGGAAATCTTCGTGGGCCGCATCCTGCCGTTCGACATGAGG
GCAGCACGCCTCTATGCCGATCTTGCCGTCCGGGCGCGTGCCGCTGGAAGGGGGTTCCCAACGCCCGATGGCTATATCGC
GGCGATCGCCGCTGCCCATGGGCTTGCCGTGGCGTCTCGCGATTCCAGTGCTTTTGCCGCCGCCGGGCTCTCCGTGATCG
ATCCCTGGACGCCGGCTGCATAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9141.47 Da        Isoelectric Point: 10.4369

>AT32913 WP_123693766.1 NZ_AP019700:c3698375-3698121 [Stella humosa]
MAAVTIRNLPEAVHRALKVRAAQHNRSAEAEMRAILEAAVRPADRLRVGSALADLSRKVGLTNADVEALDQVRDDKPADP
MGFR

Download         Length: 255 bp

>AT32913 NZ_AP019700:c3698375-3698121 [Stella humosa]
ATGGCTGCCGTCACCATCCGCAATCTCCCCGAGGCGGTGCATCGTGCCCTGAAAGTCCGGGCCGCACAGCACAATCGCAG
CGCCGAAGCGGAAATGCGGGCCATCCTGGAGGCCGCCGTGCGTCCTGCCGACCGGCTGCGCGTCGGTAGTGCGCTGGCCG
ACTTGAGCCGCAAGGTCGGGTTGACCAATGCCGATGTCGAGGCTCTTGACCAGGTCCGGGACGACAAGCCCGCCGACCCT
ATGGGCTTCCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References