Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 1227803..1228350 Replicon chromosome
Accession NZ_AP019700
Organism Stella humosa strain ATCC 43930

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag STVA_RS05820 Protein ID WP_123689529.1
Coordinates 1227803..1228108 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag STVA_RS05825 Protein ID WP_123689528.1
Coordinates 1228105..1228350 (-) Length 82 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
STVA_RS05805 1224745..1225173 + 429 WP_142235676.1 hypothetical protein -
STVA_RS27550 1225206..1225379 - 174 WP_170216435.1 hypothetical protein -
STVA_RS05810 1225376..1226398 - 1023 WP_123689531.1 CapA family protein -
STVA_RS05815 1226524..1227792 + 1269 WP_123689530.1 hydantoinase/carbamoylase family amidase -
STVA_RS05820 1227803..1228108 - 306 WP_123689529.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
STVA_RS05825 1228105..1228350 - 246 WP_123689528.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
STVA_RS05830 1228413..1229351 - 939 WP_123689527.1 pyridoxal-phosphate dependent enzyme -
STVA_RS05835 1229392..1230462 - 1071 WP_123689526.1 patatin-like phospholipase family protein -
STVA_RS05840 1230499..1232214 - 1716 WP_123689525.1 hydantoinase B/oxoprolinase family protein -
STVA_RS05845 1232211..1233035 - 825 WP_123689524.1 ABC transporter permease -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(4-92)

Antitoxin

(1-78)


Sequences


Toxin        


Download         Length: 102 a.a.        Molecular weight: 11572.18 Da        Isoelectric Point: 10.7321

>T32912 WP_123689529.1 NZ_AP019700:c1228108-1227803 [Stella humosa]
VRRLRLLPAARRDADEIWDYSADRWGSNQADEYLRALIAAGQAIADGRRQGGRIAGVRPGYWKLAVGAHLLCYRFAGDDA
LEIVRILHQRMNVESRLRRDR

Download         Length: 306 bp

>T32912 NZ_AP019700:c1228108-1227803 [Stella humosa]
GTGAGGAGGCTGCGTCTCCTGCCGGCCGCCCGCAGGGATGCTGACGAGATCTGGGACTATTCTGCAGACCGCTGGGGTAG
CAACCAGGCGGACGAGTACCTGCGAGCCCTGATCGCCGCCGGACAGGCGATAGCGGATGGCCGGCGGCAGGGGGGCAGGA
TCGCGGGCGTCCGGCCCGGCTATTGGAAGCTCGCCGTCGGCGCCCACCTTCTCTGCTACCGCTTCGCAGGGGACGATGCG
CTCGAAATCGTCCGCATCCTTCATCAGCGGATGAACGTCGAAAGCCGGCTGCGACGGGATCGGTAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9105.04 Da        Isoelectric Point: 4.5069

>AT32912 WP_123689528.1 NZ_AP019700:c1228350-1228105 [Stella humosa]
MAQNTSVVLDDHFLAFVDRQLTAGRYRSASDVIQAGLHLLEDHERKIEAFRAALIEGEESGSAEDFDIERFLQEKRAGQG
Q

Download         Length: 246 bp

>AT32912 NZ_AP019700:c1228350-1228105 [Stella humosa]
ATGGCGCAGAACACCTCGGTCGTGCTCGATGACCATTTCCTGGCCTTCGTGGACCGGCAATTGACCGCTGGCAGATATCG
CTCGGCCAGCGATGTCATCCAGGCCGGCCTGCATCTGCTTGAGGATCACGAGCGCAAGATCGAGGCGTTCAGGGCCGCAC
TGATCGAGGGCGAAGAAAGCGGCTCGGCCGAAGACTTCGACATCGAGCGGTTTCTCCAGGAAAAGCGGGCCGGCCAGGGT
CAGTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References