Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | parDE/RHH(antitoxin) |
Location | 1227803..1228350 | Replicon | chromosome |
Accession | NZ_AP019700 | ||
Organism | Stella humosa strain ATCC 43930 |
Toxin (Protein)
Gene name | parE | Uniprot ID | - |
Locus tag | STVA_RS05820 | Protein ID | WP_123689529.1 |
Coordinates | 1227803..1228108 (-) | Length | 102 a.a. |
Antitoxin (Protein)
Gene name | parD | Uniprot ID | - |
Locus tag | STVA_RS05825 | Protein ID | WP_123689528.1 |
Coordinates | 1228105..1228350 (-) | Length | 82 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
STVA_RS05805 | 1224745..1225173 | + | 429 | WP_142235676.1 | hypothetical protein | - |
STVA_RS27550 | 1225206..1225379 | - | 174 | WP_170216435.1 | hypothetical protein | - |
STVA_RS05810 | 1225376..1226398 | - | 1023 | WP_123689531.1 | CapA family protein | - |
STVA_RS05815 | 1226524..1227792 | + | 1269 | WP_123689530.1 | hydantoinase/carbamoylase family amidase | - |
STVA_RS05820 | 1227803..1228108 | - | 306 | WP_123689529.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
STVA_RS05825 | 1228105..1228350 | - | 246 | WP_123689528.1 | type II toxin-antitoxin system ParD family antitoxin | Antitoxin |
STVA_RS05830 | 1228413..1229351 | - | 939 | WP_123689527.1 | pyridoxal-phosphate dependent enzyme | - |
STVA_RS05835 | 1229392..1230462 | - | 1071 | WP_123689526.1 | patatin-like phospholipase family protein | - |
STVA_RS05840 | 1230499..1232214 | - | 1716 | WP_123689525.1 | hydantoinase B/oxoprolinase family protein | - |
STVA_RS05845 | 1232211..1233035 | - | 825 | WP_123689524.1 | ABC transporter permease | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 102 a.a. Molecular weight: 11572.18 Da Isoelectric Point: 10.7321
>T32912 WP_123689529.1 NZ_AP019700:c1228108-1227803 [Stella humosa]
VRRLRLLPAARRDADEIWDYSADRWGSNQADEYLRALIAAGQAIADGRRQGGRIAGVRPGYWKLAVGAHLLCYRFAGDDA
LEIVRILHQRMNVESRLRRDR
VRRLRLLPAARRDADEIWDYSADRWGSNQADEYLRALIAAGQAIADGRRQGGRIAGVRPGYWKLAVGAHLLCYRFAGDDA
LEIVRILHQRMNVESRLRRDR
Download Length: 306 bp
>T32912 NZ_AP019700:c1228108-1227803 [Stella humosa]
GTGAGGAGGCTGCGTCTCCTGCCGGCCGCCCGCAGGGATGCTGACGAGATCTGGGACTATTCTGCAGACCGCTGGGGTAG
CAACCAGGCGGACGAGTACCTGCGAGCCCTGATCGCCGCCGGACAGGCGATAGCGGATGGCCGGCGGCAGGGGGGCAGGA
TCGCGGGCGTCCGGCCCGGCTATTGGAAGCTCGCCGTCGGCGCCCACCTTCTCTGCTACCGCTTCGCAGGGGACGATGCG
CTCGAAATCGTCCGCATCCTTCATCAGCGGATGAACGTCGAAAGCCGGCTGCGACGGGATCGGTAG
GTGAGGAGGCTGCGTCTCCTGCCGGCCGCCCGCAGGGATGCTGACGAGATCTGGGACTATTCTGCAGACCGCTGGGGTAG
CAACCAGGCGGACGAGTACCTGCGAGCCCTGATCGCCGCCGGACAGGCGATAGCGGATGGCCGGCGGCAGGGGGGCAGGA
TCGCGGGCGTCCGGCCCGGCTATTGGAAGCTCGCCGTCGGCGCCCACCTTCTCTGCTACCGCTTCGCAGGGGACGATGCG
CTCGAAATCGTCCGCATCCTTCATCAGCGGATGAACGTCGAAAGCCGGCTGCGACGGGATCGGTAG
Antitoxin
Download Length: 82 a.a. Molecular weight: 9105.04 Da Isoelectric Point: 4.5069
>AT32912 WP_123689528.1 NZ_AP019700:c1228350-1228105 [Stella humosa]
MAQNTSVVLDDHFLAFVDRQLTAGRYRSASDVIQAGLHLLEDHERKIEAFRAALIEGEESGSAEDFDIERFLQEKRAGQG
Q
MAQNTSVVLDDHFLAFVDRQLTAGRYRSASDVIQAGLHLLEDHERKIEAFRAALIEGEESGSAEDFDIERFLQEKRAGQG
Q
Download Length: 246 bp
>AT32912 NZ_AP019700:c1228350-1228105 [Stella humosa]
ATGGCGCAGAACACCTCGGTCGTGCTCGATGACCATTTCCTGGCCTTCGTGGACCGGCAATTGACCGCTGGCAGATATCG
CTCGGCCAGCGATGTCATCCAGGCCGGCCTGCATCTGCTTGAGGATCACGAGCGCAAGATCGAGGCGTTCAGGGCCGCAC
TGATCGAGGGCGAAGAAAGCGGCTCGGCCGAAGACTTCGACATCGAGCGGTTTCTCCAGGAAAAGCGGGCCGGCCAGGGT
CAGTGA
ATGGCGCAGAACACCTCGGTCGTGCTCGATGACCATTTCCTGGCCTTCGTGGACCGGCAATTGACCGCTGGCAGATATCG
CTCGGCCAGCGATGTCATCCAGGCCGGCCTGCATCTGCTTGAGGATCACGAGCGCAAGATCGAGGCGTTCAGGGCCGCAC
TGATCGAGGGCGAAGAAAGCGGCTCGGCCGAAGACTTCGACATCGAGCGGTTTCTCCAGGAAAAGCGGGCCGGCCAGGGT
CAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|
Antitoxin
Source | ID | Structure |
---|