Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2026008..2026155 Replicon chromosome
Accession NZ_AP019687
Organism Klebsiella quasipneumoniae strain SNI47

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2026049..2026151 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2026008..2026155 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
TMSI_RS10115 2021146..2023206 + 2061 WP_101861959.1 oligopeptidase B -
TMSI_RS10120 2023210..2023869 - 660 WP_101861958.1 exodeoxyribonuclease X -
TMSI_RS10125 2023948..2024178 - 231 WP_002911406.1 DNA polymerase III subunit theta -
TMSI_RS10130 2024291..2024665 + 375 WP_101861957.1 CopC domain-containing protein YobA -
TMSI_RS10135 2024669..2025535 + 867 WP_151819733.1 copper homeostasis membrane protein CopD -
TMSI_RS10140 2025552..2025890 + 339 WP_002911404.1 YebY family protein -
- 2026008..2026155 - 148 - - Antitoxin
- 2026049..2026151 + 103 - - Toxin
TMSI_RS10150 2026530..2026673 - 144 WP_032425946.1 Ecr family regulatory small membrane protein -
TMSI_RS10155 2026774..2027742 - 969 WP_072413392.1 VirK/YbjX family protein -
TMSI_RS10160 2027899..2028552 + 654 WP_023290232.1 protein-serine/threonine phosphatase -
TMSI_RS10165 2028549..2028740 - 192 WP_002911395.1 YebW family protein -
TMSI_RS10170 2028838..2029077 - 240 WP_002911393.1 YebV family protein -
TMSI_RS10175 2029193..2030623 - 1431 WP_044523969.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T32888 NZ_AP019687:2026049-2026151 [Klebsiella quasipneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 148 bp

>AT32888 NZ_AP019687:c2026155-2026008 [Klebsiella quasipneumoniae]
AGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGTCTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References