Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | EcnAB/- |
Location | 4619402..4619765 | Replicon | chromosome |
Accession | NZ_AP019684 | ||
Organism | Xanthomonas campestris pv. campestris strain MAFF302021 |
Toxin (Protein)
Gene name | EcnB | Uniprot ID | G0CKD4 |
Locus tag | GDM11_RS20915 | Protein ID | WP_011270059.1 |
Coordinates | 4619402..4619536 (-) | Length | 45 a.a. |
Antitoxin (Protein)
Gene name | EcnA | Uniprot ID | Q8P3Z2 |
Locus tag | GDM11_RS20920 | Protein ID | WP_011038999.1 |
Coordinates | 4619613..4619765 (-) | Length | 51 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
GDM11_RS20895 | 4614667..4616319 | - | 1653 | WP_172973909.1 | M28 family peptidase | - |
GDM11_RS20900 | 4616483..4617427 | - | 945 | WP_172973853.1 | MBL fold metallo-hydrolase | - |
GDM11_RS20905 | 4617511..4618800 | - | 1290 | WP_172973854.1 | tryptophan--tRNA ligase | - |
GDM11_RS20910 | 4618960..4619169 | - | 210 | WP_011038998.1 | CsbD family protein | - |
GDM11_RS20915 | 4619402..4619536 | - | 135 | WP_011270059.1 | entericidin A/B family lipoprotein | Toxin |
GDM11_RS20920 | 4619613..4619765 | - | 153 | WP_011038999.1 | entericidin A/B family lipoprotein | Antitoxin |
GDM11_RS20925 | 4619876..4620799 | - | 924 | WP_011039000.1 | arginase | - |
GDM11_RS20930 | 4621113..4621547 | + | 435 | Protein_3931 | roadblock/LC7 domain-containing protein | - |
GDM11_RS20935 | 4621661..4622020 | + | 360 | WP_011039002.1 | hypothetical protein | - |
GDM11_RS20940 | 4622123..4623040 | + | 918 | WP_011039003.1 | hypothetical protein | - |
GDM11_RS20945 | 4623037..4623579 | + | 543 | WP_011039004.1 | GTPase | - |
GDM11_RS20950 | 4623914..4624597 | + | 684 | WP_011039005.1 | dTMP kinase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 45 a.a. Molecular weight: 4431.27 Da Isoelectric Point: 9.3487
>T32886 WP_011270059.1 NZ_AP019684:c4619536-4619402 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK
Download Length: 135 bp
>T32886 NZ_AP019684:c4619536-4619402 [Xanthomonas campestris pv. campestris]
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA
Antitoxin
Download Length: 51 a.a. Molecular weight: 5173.15 Da Isoelectric Point: 8.2782
>AT32886 WP_011038999.1 NZ_AP019684:c4619765-4619613 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC
Download Length: 153 bp
>AT32886 NZ_AP019684:c4619765-4619613 [Xanthomonas campestris pv. campestris]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTAA
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0H2XDQ0 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | Q8P3Z2 |