32886

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4619402..4619765 Replicon chromosome
Accession NZ_AP019684
Organism Xanthomonas campestris pv. campestris strain MAFF302021

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag GDM11_RS20915 Protein ID WP_011270059.1
Coordinates 4619402..4619536 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag GDM11_RS20920 Protein ID WP_011038999.1
Coordinates 4619613..4619765 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GDM11_RS20895 4614667..4616319 - 1653 WP_172973909.1 M28 family peptidase -
GDM11_RS20900 4616483..4617427 - 945 WP_172973853.1 MBL fold metallo-hydrolase -
GDM11_RS20905 4617511..4618800 - 1290 WP_172973854.1 tryptophan--tRNA ligase -
GDM11_RS20910 4618960..4619169 - 210 WP_011038998.1 CsbD family protein -
GDM11_RS20915 4619402..4619536 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
GDM11_RS20920 4619613..4619765 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
GDM11_RS20925 4619876..4620799 - 924 WP_011039000.1 arginase -
GDM11_RS20930 4621113..4621547 + 435 Protein_3931 roadblock/LC7 domain-containing protein -
GDM11_RS20935 4621661..4622020 + 360 WP_011039002.1 hypothetical protein -
GDM11_RS20940 4622123..4623040 + 918 WP_011039003.1 hypothetical protein -
GDM11_RS20945 4623037..4623579 + 543 WP_011039004.1 GTPase -
GDM11_RS20950 4623914..4624597 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T32886 WP_011270059.1 NZ_AP019684:c4619536-4619402 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T32886 NZ_AP019684:c4619536-4619402 [Xanthomonas campestris pv. campestris]
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT32886 WP_011038999.1 NZ_AP019684:c4619765-4619613 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT32886 NZ_AP019684:c4619765-4619613 [Xanthomonas campestris pv. campestris]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0


Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References