Detailed information of TA system TA032885

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacAT/DUF1778(antitoxin)
• Location: 1242073..1242851
• Replicon: chromosome
• Accession: NZ_AP019684
• Organism: Xanthomonas campestris pv. campestris strain MAFF302021

Toxin (Protein)

• Gene name: TacT2
• Uniprot ID: Q8P667
• Locus tag: GDM11_RS05470
• Protein ID: WP_011038220.1
• Coordinates: 1242073..1242564 (-)
• Length: 164 a.a.

Antitoxin (Protein)

• Gene name: TacA2
• Uniprot ID: Q8P668
• Locus tag: GDM11_RS05475
• Protein ID: WP_011038219.1
• Coordinates: 1242561..1242851 (-)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GDM11_RS05450	1238324..1239199	+	876	WP_016945000.1	30S ribosomal protein S6--L-glutamate ligase	-
GDM11_RS05455	1239422..1239895	+	474	WP_012437597.1	hypothetical protein	-
GDM11_RS05460	1239926..1240603	+	678	WP_003490678.1	response regulator transcription factor	-
GDM11_RS05465	1240596..1241930	+	1335	WP_012437598.1	HAMP domain-containing histidine kinase	-
GDM11_RS05470	1242073..1242564	-	492	WP_011038220.1	GNAT family N-acetyltransferase	Toxin
GDM11_RS05475	1242561..1242851	-	291	WP_011038219.1	DUF1778 domain-containing protein	Antitoxin
GDM11_RS05480	1242926..1243327	-	402	WP_012437599.1	type I toxin-antitoxin system SymE family toxin	-
GDM11_RS05490	1243859..1244482	-	624	WP_011038217.1	dephospho-CoA kinase	-
GDM11_RS05495	1244496..1245359	-	864	WP_012437600.1	A24 family peptidase	-
GDM11_RS05500	1245366..1246627	-	1262	Protein_1026	type II secretion system F family protein	-
GDM11_RS05505	1246979..1247392	+	414	WP_012437602.1	pilin	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1199923..1251326	51403

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (42-144)

Antitoxin

• Vibrio phage ICP1, Orf50 (1-95)

Sequences

Toxin

Protein

• Length: 164 a.a.
• Molecular weight: 17638.31 Da
• Isoelectric Point: 8.1192

>T32885 WP_011038220.1 NZ_AP019684:c1242564-1242073 [Xanthomonas campestris pv. campestris]
MTVSAPEPLTAHHRVEPFASGVESLDHWLKRRALKNQATGASRTFVACEDDRVVAYYALASSAVAVDATPGRFRRNMPDP
IPVVVLGRLAVDQSLHGRGFGRALMQDAGKRILHAADTIGIRGLLVHALSADAKAFYERIGFEPSPLDPMVLVVTLEDLK
ASL

Nucleotide

• Length: 492 bp

>T32885 NZ_AP019684:c1242564-1242073 [Xanthomonas campestris pv. campestris]
ATGACGGTATCGGCGCCGGAACCGCTGACAGCGCATCACCGGGTCGAACCGTTCGCATCGGGCGTGGAGAGCCTGGATCA
CTGGCTCAAGCGCCGCGCCCTGAAAAATCAGGCAACCGGTGCGTCACGGACCTTCGTTGCCTGCGAGGATGACCGCGTGG
TGGCCTATTACGCCCTGGCGTCGAGTGCGGTCGCCGTGGACGCGACGCCCGGCCGCTTCCGTCGCAACATGCCGGACCCG
ATCCCCGTGGTGGTGCTTGGGAGGCTTGCTGTTGACCAATCCCTGCATGGCAGAGGTTTTGGCCGCGCCCTGATGCAGGA
TGCTGGCAAGCGCATCTTGCATGCGGCCGACACCATCGGCATTCGCGGGCTGCTCGTGCATGCGCTCTCGGCGGACGCCA
AGGCGTTTTACGAGCGCATCGGCTTCGAACCTTCCCCGCTGGATCCCATGGTGCTGGTCGTCACGCTGGAAGACCTGAAA
GCCAGTCTGTGA

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 10678.23 Da
• Isoelectric Point: 10.5480

>AT32885 WP_011038219.1 NZ_AP019684:c1242851-1242561 [Xanthomonas campestris pv. campestris]
MSTPNTTPGKRETLNLRIKPEERSLIDRAAKARGKNRTDFMLDAARSAAEEALLDQTLITASPDAYAAFLARLDMPPQPN
ARLRKTMQTPAPWEKA

Nucleotide

• Length: 291 bp

>AT32885 NZ_AP019684:c1242851-1242561 [Xanthomonas campestris pv. campestris]
ATGTCCACACCCAACACTACGCCTGGCAAGCGCGAAACCTTGAATCTCCGCATCAAGCCGGAGGAGCGCAGCCTGATCGA
CCGGGCCGCCAAGGCGCGCGGGAAGAACCGCACCGATTTCATGCTGGACGCAGCGCGCTCGGCGGCCGAGGAAGCCTTGC
TGGACCAGACCCTCATCACGGCCAGCCCGGACGCCTACGCCGCCTTTTTGGCACGGCTGGACATGCCGCCGCAGCCGAAC
GCGCGCCTGCGCAAGACGATGCAGACGCCCGCTCCTTGGGAGAAGGCATGA

Structures

Toxin

• AlphaFold DB: Q8P667

Antitoxin

• AlphaFold DB: Q8P668