Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1991147..1991292 | Replicon | chromosome |
| Accession | NZ_AP019665 | ||
| Organism | Klebsiella pneumoniae strain TA6363 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1991183..1991285 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1991147..1991292 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| TA6363_RS09635 | 1986277..1988337 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| TA6363_RS09640 | 1988341..1989000 | - | 660 | WP_038431281.1 | exodeoxyribonuclease X | - |
| TA6363_RS09645 | 1989079..1989309 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| TA6363_RS09650 | 1989422..1989796 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| TA6363_RS09655 | 1989800..1990669 | + | 870 | WP_004175431.1 | copper homeostasis membrane protein CopD | - |
| TA6363_RS09660 | 1990686..1991024 | + | 339 | WP_016529031.1 | YebY family protein | - |
| - | 1991147..1991292 | - | 146 | - | - | Antitoxin |
| - | 1991183..1991285 | + | 103 | - | - | Toxin |
| TA6363_RS09665 | 1991660..1991803 | - | 144 | WP_163584243.1 | Ecr family regulatory small membrane protein | - |
| TA6363_RS09670 | 1991908..1992876 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| TA6363_RS09675 | 1993033..1993599 | + | 567 | WP_094935968.1 | metallophosphoesterase | - |
| TA6363_RS09680 | 1993596..1993787 | - | 192 | WP_002911395.1 | YebW family protein | - |
| TA6363_RS09685 | 1993885..1994124 | - | 240 | WP_002911393.1 | YebV family protein | - |
| TA6363_RS09690 | 1994240..1995673 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T32825 NZ_AP019665:1991183-1991285 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT32825 NZ_AP019665:c1991292-1991147 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
