Detailed information of TA system TA032819

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-YefM
• Location: 1002681..1003226
• Replicon: chromosome
• Accession: NZ_AP019658
• Organism: Vibrio ponticus strain DSM 16217

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: GZN30_RS18620
• Protein ID: WP_075647672.1
• Coordinates: 1002930..1003226 (+)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: GZN30_RS18615
• Protein ID: WP_075647673.1
• Coordinates: 1002681..1002923 (+)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GZN30_RS18570	997955..998449	-	495	WP_075651169.1	GNAT family N-acetyltransferase	-
GZN30_RS18575	998618..999055	-	438	WP_075651171.1	hydrogenase	-
GZN30_RS18580	999160..999525	-	366	WP_075651173.1	hypothetical protein	-
GZN30_RS18585	999761..1000102	-	342	WP_161987116.1	hypothetical protein	-
GZN30_RS18590	1000224..1000640	-	417	WP_075647677.1	hypothetical protein	-
GZN30_RS18595	1000839..1001255	-	417	WP_075647676.1	hypothetical protein	-
GZN30_RS18600	1001275..1001634	-	360	WP_075647675.1	RidA family protein	-
GZN30_RS18605	1001727..1001933	+	207	Protein_808	IS110 family transposase	-
GZN30_RS18610	1001965..1002291	-	327	WP_075647674.1	hypothetical protein	-
GZN30_RS18615	1002681..1002923	+	243	WP_075647673.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
GZN30_RS18620	1002930..1003226	+	297	WP_075647672.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
GZN30_RS18625	1003804..1004106	-	303	WP_075647671.1	type II toxin-antitoxin system RelE/ParE family toxin	-
GZN30_RS18630	1004094..1004351	-	258	WP_005448240.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
GZN30_RS18635	1004477..1004617	+	141	Protein_814	IS110 family transposase	-
GZN30_RS18640	1005087..1005833	-	747	WP_075647670.1	DUF2971 domain-containing protein	-
GZN30_RS18645	1006286..1007242	+	957	WP_075650306.1	IS110 family transposase	-
GZN30_RS18650	1007275..1007796	-	522	WP_139312260.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	999761..1011329	11568

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-93)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-63)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 11225.87 Da
• Isoelectric Point: 9.6267

>T32819 WP_075647672.1 NZ_AP019658:1002930-1003226 [Vibrio ponticus]
MQKNKYKLSKLAQAHLRKIKSYTVNNFSEMQWNNYKDTLLTGFQMLADNPAVGRSCDEIYPSGFYFPVGKHTAYFTKEDG
FILVVAVLGQSQLPQNQL

Nucleotide

• Length: 297 bp

>T32819 NZ_AP019658:1002930-1003226 [Vibrio ponticus]
ATGCAAAAGAATAAATACAAACTAAGTAAATTGGCTCAGGCTCATTTACGAAAAATTAAAAGCTATACCGTCAACAACTT
TTCTGAAATGCAGTGGAACAACTATAAAGATACATTGCTAACTGGGTTTCAAATGCTTGCCGACAATCCAGCCGTAGGTC
GCAGTTGCGATGAGATTTATCCAAGCGGTTTCTATTTTCCGGTAGGAAAACACACAGCTTACTTTACAAAAGAAGACGGT
TTTATTTTAGTTGTGGCTGTACTTGGTCAATCACAACTCCCACAAAACCAATTGTAG

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 8875.07 Da
• Isoelectric Point: 5.0621

>AT32819 WP_075647673.1 NZ_AP019658:1002681-1002923 [Vibrio ponticus]
MHTLTANDAKRNFGELLLSAQREPVKISKNSKDAVVVMSIKDYEELEAMKTDYLKHCFESAKQDLAQGNVVDGGDFLSAL

Nucleotide

• Length: 243 bp

>AT32819 NZ_AP019658:1002681-1002923 [Vibrio ponticus]
ATGCACACACTAACAGCAAATGATGCAAAGCGTAACTTTGGTGAGCTACTTCTAAGCGCCCAACGTGAGCCAGTAAAGAT
TAGCAAAAACAGTAAAGATGCCGTAGTGGTAATGTCTATCAAAGACTATGAAGAACTAGAGGCAATGAAAACTGATTACC
TTAAACATTGTTTCGAGTCAGCTAAACAAGACTTAGCACAAGGCAATGTAGTTGACGGTGGAGATTTCCTAAGCGCCTTG
TAA