Detailed information of TA system TA032817

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-yefM/YoeB-RelB
• Location: 1843185..1843701
• Replicon: chromosome
• Accession: NZ_AP019654
• Organism: Vibrio panuliri strain JCM 19500

Toxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: GZK95_RS08400
• Protein ID: WP_075716420.1
• Coordinates: 1843185..1843454 (-)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: GZK95_RS08405
• Protein ID: WP_075707683.1
• Coordinates: 1843447..1843701 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GZK95_RS08375	1839383..1840135	-	753	WP_075716417.1	PhzF family phenazine biosynthesis protein	-
GZK95_RS08380	1840306..1840764	-	459	WP_075716418.1	HPP family protein	-
GZK95_RS08385	1840867..1841418	+	552	WP_075707675.1	TetR/AcrR family transcriptional regulator	-
GZK95_RS08390	1841443..1841796	-	354	WP_075707677.1	DUF1428 domain-containing protein	-
GZK95_RS08395	1842031..1842735	-	705	WP_075716419.1	hypothetical protein	-
GZK95_RS08400	1843185..1843454	-	270	WP_075716420.1	Txe/YoeB family addiction module toxin	Toxin
GZK95_RS08405	1843447..1843701	-	255	WP_075707683.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
GZK95_RS08410	1844036..1844542	-	507	WP_161987206.1	DUF1643 domain-containing protein	-
GZK95_RS08415	1844727..1844945	-	219	WP_075716422.1	hypothetical protein	-
GZK95_RS08420	1845037..1845225	+	189	Protein_1642	IS110 family transposase	-
GZK95_RS08425	1845343..1846215	-	873	WP_075716424.1	hypothetical protein	-
GZK95_RS08430	1846310..1846456	+	147	Protein_1644	IS110 family transposase	-
GZK95_RS08435	1846634..1847482	-	849	WP_075716426.1	hypothetical protein	-
GZK95_RS08440	1847570..1847752	+	183	Protein_1646	IS110 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1840867..1849631	8764

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (10-89)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 10602.99 Da
• Isoelectric Point: 7.9816

>T32817 WP_075716420.1 NZ_AP019654:c1843454-1843185 [Vibrio panuliri]
MSSGQRLLSWTDDAWDDYLYWQTQDKKTLKRINKLINDVKRSLFEGIGKPEALKENLSGFWSRRIDDTNRLVYAVDDQVI
TIISCRYHY

Nucleotide

• Length: 270 bp

>T32817 NZ_AP019654:c1843454-1843185 [Vibrio panuliri]
ATGAGTAGTGGTCAACGTTTACTATCTTGGACTGACGATGCTTGGGATGACTACTTGTACTGGCAAACCCAAGACAAGAA
AACACTGAAACGCATCAACAAGCTGATCAACGATGTTAAGCGTTCGCTATTTGAGGGCATTGGTAAGCCTGAGGCACTAA
AAGAAAACTTATCTGGTTTTTGGTCTCGTCGTATTGATGACACCAATAGGCTTGTCTATGCCGTTGATGATCAAGTAATC
ACGATAATCTCGTGTCGCTACCATTACTAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9497.66 Da
• Isoelectric Point: 5.0623

>AT32817 WP_075707683.1 NZ_AP019654:c1843701-1843447 [Vibrio panuliri]
MRIVSFTEARNSLKAVLDGVVNDADTTIITRRDSEDAVVMSLDYYNSLMETVHLLRSPQNAEHLNRSIAQYRAGKTTARE
LIDE

Nucleotide

• Length: 255 bp

>AT32817 NZ_AP019654:c1843701-1843447 [Vibrio panuliri]
ATGAGAATCGTATCTTTTACTGAAGCTAGAAACAGTCTTAAAGCGGTTTTAGACGGTGTTGTTAATGATGCTGACACCAC
TATAATTACTCGCCGTGACTCAGAAGATGCAGTAGTTATGTCCCTAGATTATTACAATAGTCTTATGGAGACCGTCCATT
TACTTCGCTCACCACAAAATGCTGAACATTTAAATCGTTCTATAGCGCAGTATCGTGCTGGTAAAACCACGGCACGAGAG
TTGATAGATGAGTAG