32816

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 1388138..1389485 Replicon chromosome
Accession NZ_AP019654
Organism Vibrio panuliri strain JCM 19500

Toxin (Protein)


Gene name sanaT Uniprot ID -
Locus tag GZK95_RS06330 Protein ID WP_075712819.1
Coordinates 1388544..1389485 (+) Length 314 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID -
Locus tag GZK95_RS06325 Protein ID WP_075712817.1
Coordinates 1388138..1388542 (+) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GZK95_RS06295 1383753..1384193 - 441 WP_197740171.1 NUDIX hydrolase -
GZK95_RS06300 1384355..1384576 + 222 WP_139315069.1 hypothetical protein -
GZK95_RS06305 1384666..1385625 - 960 WP_075715321.1 nitrilase family protein -
GZK95_RS06310 1385725..1386600 + 876 WP_075715320.1 LysR family transcriptional regulator -
GZK95_RS06315 1386705..1387043 - 339 WP_075715319.1 cytosolic protein -
GZK95_RS06320 1387361..1387976 + 616 Protein_1224 tyrosine-type recombinase/integrase -
GZK95_RS06325 1388138..1388542 + 405 WP_075712817.1 S-adenosylhomocysteine hydrolase Antitoxin
GZK95_RS06330 1388544..1389485 + 942 WP_075712819.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
GZK95_RS06335 1389506..1391038 + 1533 WP_075712821.1 type I restriction-modification system subunit M -
GZK95_RS06340 1391028..1392260 + 1233 WP_075712823.1 restriction endonuclease subunit S -
GZK95_RS06345 1392403..1394247 + 1845 WP_075712825.1 cold shock domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(32-300)

Antitoxin

Protein of unknown function DUF6088

(7-130)


Sequences

Toxin        


Download         Length: 314 a.a.        Molecular weight: 35764.23 Da        Isoelectric Point: 5.3047

>T32816 WP_075712819.1 NZ_AP019654:1388544-1389485 [Vibrio panuliri]
MNTLKQQFLEVSDALELGNPAIIEKDYWVVALLAELAKVSPEHHQMVFSGGTALAKSNVKILRMSEDVDIKLIPNQAFDE
LSRAKKKAARKACVNEIEQAITQSELFTVEERSVRDEYRYVEFELKYTQQFSQAPCLRPIIKLELIETIPLLDVESRSIQ
SLVAELYQKPQEISAFDCVSIHATLVEKIISMLRRTMSVKRNTERSDDVALVRHIYDVHCITKLSMPELNSIVGLFKAVL
AEDIARFGNQHAEFVANPKQELQLGLKELEENAIFRQRFQEFVTPMVFNTEPHDFDTCFASFKRIAASLIETI

Download         Length: 942 bp

>T32816 NZ_AP019654:1388544-1389485 [Vibrio panuliri]
ATGAACACACTAAAACAACAATTCCTTGAGGTTTCCGATGCGCTTGAGCTTGGAAACCCAGCCATTATTGAAAAAGATTA
CTGGGTCGTTGCCTTACTAGCCGAACTAGCGAAAGTTTCTCCTGAGCATCATCAAATGGTGTTTTCTGGCGGCACGGCGT
TGGCGAAATCAAACGTTAAAATTTTAAGAATGTCGGAAGATGTGGATATAAAACTCATCCCCAACCAAGCATTTGATGAA
CTGAGCCGTGCGAAAAAGAAAGCCGCGAGAAAGGCATGTGTTAACGAGATTGAACAGGCGATCACTCAGTCAGAGCTATT
TACCGTTGAAGAGCGTTCTGTGCGAGATGAGTACCGCTACGTCGAGTTTGAACTTAAATACACGCAGCAGTTTAGCCAAG
CACCCTGCCTTCGCCCCATTATCAAGTTAGAGTTAATCGAAACCATTCCATTATTGGATGTGGAGTCGCGCAGCATTCAA
TCACTGGTAGCAGAGTTGTACCAAAAACCACAAGAAATAAGTGCGTTTGATTGCGTCTCTATCCATGCCACATTGGTTGA
AAAAATCATTTCGATGCTGCGTCGTACCATGTCGGTAAAACGCAATACGGAGCGAAGCGATGATGTTGCTTTAGTTCGCC
ACATCTACGATGTGCACTGTATAACAAAGCTCTCAATGCCTGAACTCAACTCGATTGTCGGTCTATTCAAAGCAGTATTG
GCAGAAGATATTGCCCGCTTTGGCAATCAGCATGCGGAGTTTGTTGCCAACCCCAAACAAGAGCTACAACTTGGCCTCAA
AGAGCTTGAGGAAAATGCAATATTCCGCCAACGTTTTCAAGAATTTGTCACGCCAATGGTGTTTAACACCGAACCCCATG
ATTTTGATACCTGCTTTGCCTCATTTAAACGCATTGCAGCATCGCTAATTGAAACCATTTAA

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 15158.54 Da        Isoelectric Point: 10.6258

>AT32816 WP_075712817.1 NZ_AP019654:1388138-1388542 [Vibrio panuliri]
MTAVDRICQKIKRSRRYVFERKDFDGFASYDQIGRALRQLVQQGELMKLGYGLYTKARINSLTGKPMPTNPGGTDALVRE
ILKMKGVHFEMDSLSLQSLSGTSTQIPSSIQYSWDPKQFNRKLVVGSRVLNLPS

Download         Length: 405 bp

>AT32816 NZ_AP019654:1388138-1388542 [Vibrio panuliri]
ATGACAGCAGTAGACCGCATTTGTCAAAAGATAAAGCGTTCAAGACGTTATGTGTTTGAACGCAAAGACTTTGATGGATT
TGCAAGTTACGACCAAATAGGTCGGGCACTCAGGCAGCTTGTGCAGCAAGGGGAATTAATGAAGCTTGGTTATGGTTTGT
ATACCAAAGCAAGAATCAATAGTCTCACAGGTAAGCCTATGCCCACCAATCCAGGTGGCACCGATGCTCTTGTGCGAGAA
ATTCTTAAAATGAAAGGCGTTCATTTTGAGATGGATAGTCTATCGCTACAAAGTCTTTCAGGCACGAGTACCCAAATTCC
ATCTTCTATTCAGTATTCATGGGATCCAAAACAGTTTAATCGCAAACTGGTTGTCGGTAGCCGTGTGCTGAACTTACCTA
GTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References