Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 3992195..3992874 Replicon chromosome
Accession NZ_AP019632
Organism Enterobacter asburiae strain 1808-013

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag FOY96_RS19065 Protein ID WP_090048330.1
Coordinates 3992195..3992512 (-) Length 106 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag FOY96_RS19070 Protein ID WP_090048329.1
Coordinates 3992548..3992874 (-) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOY96_RS19035 3988137..3988598 + 462 WP_197736963.1 PAAR domain-containing protein -
FOY96_RS19040 3988609..3989745 + 1137 WP_143347599.1 PAAR domain-containing protein -
FOY96_RS19045 3989729..3990004 + 276 WP_143347600.1 hypothetical protein -
FOY96_RS19055 3990832..3991620 - 789 WP_090048331.1 helix-turn-helix domain-containing protein -
FOY96_RS19060 3991756..3992056 - 301 Protein_3688 restriction endonuclease subunit M -
FOY96_RS19065 3992195..3992512 - 318 WP_090048330.1 TA system toxin CbtA family protein Toxin
FOY96_RS19070 3992548..3992874 - 327 WP_090048329.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
FOY96_RS19075 3992921..3993394 - 474 WP_090048327.1 DNA repair protein RadC -
FOY96_RS19080 3993465..3994286 - 822 WP_023334632.1 DUF945 domain-containing protein -
FOY96_RS19090 3994979..3995818 - 840 WP_090048323.1 hypothetical protein -
FOY96_RS19095 3995878..3996312 - 435 WP_090048321.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-105)

Antitoxin

Antitoxin CbeA

(8-107)


Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 11964.83 Da        Isoelectric Point: 7.8561

>T32800 WP_090048330.1 NZ_AP019632:c3992512-3992195 [Enterobacter asburiae]
MKTLPATTQKAAKPCPTPVVVWQTLLTRLLEQHYGLTLNDTPFCDETVIQEHINAGITLADAVNFLVEKYELVRIDRRGF
SWQEQSPYLRAVDILRARQATGLLR

Download         Length: 318 bp

>T32800 NZ_AP019632:c3992512-3992195 [Enterobacter asburiae]
ATGAAAACCTTACCTGCAACAACTCAGAAGGCGGCTAAGCCATGTCCGACGCCCGTGGTTGTCTGGCAAACGCTACTTAC
CCGTCTGCTGGAGCAACACTATGGCCTGACTCTGAACGACACGCCGTTCTGCGATGAAACAGTCATTCAGGAACATATTA
ACGCCGGAATCACACTGGCAGATGCCGTTAACTTTCTGGTGGAAAAGTACGAACTGGTTCGTATTGATCGCAGAGGGTTT
AGCTGGCAGGAACAATCGCCTTATCTGCGGGCTGTAGACATTTTGCGGGCGCGACAGGCAACGGGTCTGTTACGATAA

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12373.96 Da        Isoelectric Point: 6.3221

>AT32800 WP_090048329.1 NZ_AP019632:c3992874-3992548 [Enterobacter asburiae]
MDKYDPTEWGLRRDITPRVGARLVQEGNQLHYLADRAGVTGTFKEAESRKLNAAFPHFVEHMELMLLSGELNSRYAHCVT
LYHDGFTCEADTLGSYGYVYIVIYPTQR

Download         Length: 327 bp

>AT32800 NZ_AP019632:c3992874-3992548 [Enterobacter asburiae]
ATGGATAAATACGATCCCACTGAATGGGGGCTTCGACGTGATATCACGCCGCGTGTAGGAGCACGACTGGTACAGGAAGG
AAATCAACTGCATTACCTGGCTGACCGGGCCGGTGTCACCGGCACCTTTAAGGAAGCTGAGAGCCGCAAACTGAATGCAG
CATTTCCGCATTTCGTGGAGCATATGGAGTTAATGTTACTCTCCGGGGAACTAAACTCCCGTTATGCGCACTGTGTCACC
CTGTACCATGATGGATTTACCTGTGAAGCCGACACGCTTGGCTCTTATGGTTACGTCTACATCGTCATTTACCCTACTCA
ACGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References