Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-VagC |
| Location | 5370371..5371005 | Replicon | chromosome |
| Accession | NZ_AP019411 | ||
| Organism | Pseudomonas syringae pv. actinidiae strain MAFF613020 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | M2494_RS23950 | Protein ID | WP_003380365.1 |
| Coordinates | 5370371..5370775 (-) | Length | 135 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | Q888H8 |
| Locus tag | M2494_RS23955 | Protein ID | WP_003380366.1 |
| Coordinates | 5370775..5371005 (-) | Length | 77 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M2494_RS23915 (KPSA1B_104872) | 5365801..5366283 | + | 483 | WP_003380358.1 | PAS domain-containing protein | - |
| M2494_RS23920 (KPSA1B_104873) | 5366379..5367635 | + | 1257 | WP_003380359.1 | 3-phosphoshikimate 1-carboxyvinyltransferase | - |
| M2494_RS23925 | 5367700..5367936 | + | 237 | WP_003380360.1 | hypothetical protein | - |
| M2494_RS23930 (KPSA1B_104874) | 5368012..5368674 | - | 663 | WP_003380361.1 | ChrR family anti-sigma-E factor | - |
| M2494_RS23935 (KPSA1B_104875) | 5368674..5369186 | - | 513 | WP_003380362.1 | sigma-70 family RNA polymerase sigma factor | - |
| M2494_RS23940 | 5369422..5369610 | - | 189 | WP_003380363.1 | hypothetical protein | - |
| M2494_RS23945 (KPSA1B_104876) | 5369609..5370184 | + | 576 | WP_003380364.1 | hypothetical protein | - |
| M2494_RS23950 (KPSA1B_104877) | 5370371..5370775 | - | 405 | WP_003380365.1 | tRNA(fMet)-specific endonuclease VapC | Toxin |
| M2494_RS23955 (KPSA1B_104878) | 5370775..5371005 | - | 231 | WP_003380366.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin |
| M2494_RS23960 (KPSA1B_104879) | 5371120..5372001 | - | 882 | WP_003380368.1 | aldose 1-epimerase | - |
| M2494_RS23965 (KPSA1B_104880) | 5371976..5372947 | - | 972 | WP_003380370.1 | DMT family transporter | - |
| M2494_RS23970 (KPSA1B_104881) | 5373031..5374311 | - | 1281 | WP_003380372.1 | TRAP transporter large permease | - |
| M2494_RS23975 (KPSA1B_104882) | 5374312..5374839 | - | 528 | WP_003380373.1 | TRAP transporter small permease | - |
| M2494_RS23980 (KPSA1B_104883) | 5374903..5375928 | - | 1026 | WP_003380375.1 | TRAP transporter substrate-binding protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 5370371..5380313 | 9942 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 135 a.a. Molecular weight: 14814.09 Da Isoelectric Point: 6.8615
>T32651 WP_003380365.1 NZ_AP019411:c5370775-5370371 [Pseudomonas syringae pv. actinidiae]
MLKYMLDTNICIFTIKNKPVSVREAFNLHHGQLCISAITLMELVYGAEKSSSPERNLAVVEGFAARLELLPYDSAAAAHT
GMIRAELARAGTPIGPYDQMIAGHARSLGLVVITNNQREFQRVEGLRVEDWVSQ
MLKYMLDTNICIFTIKNKPVSVREAFNLHHGQLCISAITLMELVYGAEKSSSPERNLAVVEGFAARLELLPYDSAAAAHT
GMIRAELARAGTPIGPYDQMIAGHARSLGLVVITNNQREFQRVEGLRVEDWVSQ
Download Length: 405 bp
>T32651 NZ_AP019411:c5370775-5370371 [Pseudomonas syringae pv. actinidiae]
ATGCTCAAATACATGCTCGACACCAATATTTGCATCTTCACTATCAAGAACAAGCCGGTGTCGGTACGTGAGGCCTTCAA
CCTTCATCACGGGCAGCTGTGTATCAGCGCGATCACGTTGATGGAGCTTGTTTACGGCGCAGAAAAGTCTTCCAGTCCCG
AAAGAAATCTTGCTGTTGTAGAAGGTTTTGCAGCGCGTCTTGAATTGCTTCCCTACGATAGCGCCGCCGCGGCTCACACC
GGCATGATCAGAGCCGAGCTGGCCAGAGCGGGTACACCGATTGGCCCGTACGATCAAATGATTGCAGGACATGCCCGCTC
TCTTGGCCTCGTGGTCATCACCAACAACCAGCGTGAATTCCAGCGCGTCGAGGGGCTGAGGGTAGAAGACTGGGTAAGCC
AATAA
ATGCTCAAATACATGCTCGACACCAATATTTGCATCTTCACTATCAAGAACAAGCCGGTGTCGGTACGTGAGGCCTTCAA
CCTTCATCACGGGCAGCTGTGTATCAGCGCGATCACGTTGATGGAGCTTGTTTACGGCGCAGAAAAGTCTTCCAGTCCCG
AAAGAAATCTTGCTGTTGTAGAAGGTTTTGCAGCGCGTCTTGAATTGCTTCCCTACGATAGCGCCGCCGCGGCTCACACC
GGCATGATCAGAGCCGAGCTGGCCAGAGCGGGTACACCGATTGGCCCGTACGATCAAATGATTGCAGGACATGCCCGCTC
TCTTGGCCTCGTGGTCATCACCAACAACCAGCGTGAATTCCAGCGCGTCGAGGGGCTGAGGGTAGAAGACTGGGTAAGCC
AATAA
Antitoxin
Download Length: 77 a.a. Molecular weight: 8593.67 Da Isoelectric Point: 4.5557
>AT32651 WP_003380366.1 NZ_AP019411:c5371005-5370775 [Pseudomonas syringae pv. actinidiae]
MEQSTVFKSNRSQAVRLPKAVALPDDVKRVDVVAVGRTRIISPAGEMWNSWFDGESVSDDFMAEREQPVEQLRESL
MEQSTVFKSNRSQAVRLPKAVALPDDVKRVDVVAVGRTRIISPAGEMWNSWFDGESVSDDFMAEREQPVEQLRESL
Download Length: 231 bp
>AT32651 NZ_AP019411:c5371005-5370775 [Pseudomonas syringae pv. actinidiae]
ATGGAACAATCCACAGTCTTCAAAAGCAATCGAAGTCAGGCTGTTCGACTCCCAAAAGCGGTGGCATTACCCGACGACGT
GAAACGGGTAGACGTCGTAGCAGTGGGCAGGACACGCATCATTTCCCCTGCTGGTGAAATGTGGAACAGTTGGTTCGATG
GTGAAAGTGTCAGTGATGACTTCATGGCAGAGCGCGAGCAGCCAGTTGAACAGCTGCGCGAATCACTCTGA
ATGGAACAATCCACAGTCTTCAAAAGCAATCGAAGTCAGGCTGTTCGACTCCCAAAAGCGGTGGCATTACCCGACGACGT
GAAACGGGTAGACGTCGTAGCAGTGGGCAGGACACGCATCATTTCCCCTGCTGGTGAAATGTGGAACAGTTGGTTCGATG
GTGAAAGTGTCAGTGATGACTTCATGGCAGAGCGCGAGCAGCCAGTTGAACAGCTGCGCGAATCACTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|