32648

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/StbC(antitoxin)
Location 3443696..3444087 Replicon chromosome
Accession NZ_AP019411
Organism Pseudomonas syringae pv. actinidiae strain MAFF613020

Toxin (Protein)


Gene name vapC Uniprot ID A0A2V0QK73
Locus tag M2494_RS15200 Protein ID WP_003381344.1
Coordinates 3443941..3444087 (+) Length 49 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A2V0QXN3
Locus tag M2494_RS15195 Protein ID WP_057429693.1
Coordinates 3443696..3443944 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M2494_RS15175 3439861..3440049 - 189 Protein_3003 RHS repeat-associated core domain-containing protein -
M2494_RS15180 (KPSA1B_103097) 3440100..3441679 + 1580 WP_085991147.1 IS3-like element ISPsy31 family transposase -
M2494_RS15185 (KPSA1B_103099) 3442366..3442620 - 255 WP_003381350.1 hypothetical protein -
M2494_RS15190 (KPSA1B_103100) 3442668..3443324 - 657 WP_017684244.1 hypothetical protein -
M2494_RS15195 (KPSA1B_103101) 3443696..3443944 + 249 WP_057429693.1 Arc family DNA-binding protein Antitoxin
M2494_RS15200 (KPSA1B_103102) 3443941..3444087 + 147 WP_003381344.1 hypothetical protein Toxin
M2494_RS15205 (KPSA1B_103103) 3444382..3445317 + 936 WP_003381342.1 AvrD family protein -
M2494_RS15210 (KPSA1B_103104) 3445658..3446305 + 648 WP_003381340.1 histidine phosphatase family protein -
M2494_RS15215 (KPSA1B_103105) 3446544..3447371 + 828 WP_003381339.1 TauD/TfdA family dioxygenase -
M2494_RS15220 (KPSA1B_103106) 3447389..3448423 + 1035 WP_003381338.1 sulfotransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Arc-like DNA binding domain

(2-43)


Sequences

Toxin        


Download         Length: 49 a.a.        Molecular weight: 5447.25 Da        Isoelectric Point: 4.7333

>T32648 WP_003381344.1 NZ_AP019411:3443941-3444087 [Pseudomonas syringae pv. actinidiae]
MILLDTNVISEPQRREPNAHVLDWIDAQALETLYLAGVSVSQVKRVWA

Download         Length: 147 bp

>T32648 NZ_AP019411:3443941-3444087 [Pseudomonas syringae pv. actinidiae]
ATGATCCTGCTCGATACGAACGTAATTTCAGAACCGCAGCGCCGAGAGCCCAATGCCCACGTCCTTGACTGGATCGACGC
ACAAGCGCTGGAAACGCTTTATCTGGCCGGTGTCAGTGTCAGCCAGGTAAAGCGTGTCTGGGCATAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9117.31 Da        Isoelectric Point: 9.0330

>AT32648 WP_057429693.1 NZ_AP019411:3443696-3443944 [Pseudomonas syringae pv. actinidiae]
VNVRNLPDEVHRAIRIQAALHGRSTEAEIRDILERAARPEGRVKLGSFLASIAREVGGLTDKEHTLFENTRITSPARAVS
FE

Download         Length: 249 bp

>AT32648 NZ_AP019411:3443696-3443944 [Pseudomonas syringae pv. actinidiae]
GTGAACGTAAGAAATCTACCCGATGAAGTGCATCGGGCAATCCGCATCCAAGCTGCCCTGCACGGGCGCAGCACCGAGGC
CGAAATACGCGACATCTTGGAGCGGGCGGCGAGACCCGAGGGACGTGTGAAACTTGGCTCGTTCCTGGCTTCTATTGCCC
GTGAGGTTGGTGGTCTGACCGATAAAGAACACACCTTGTTTGAGAACACGCGCATCACGTCTCCGGCCCGTGCGGTGAGC
TTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2V0QK73

Antitoxin

Source ID Structure
AlphaFold DB A0A2V0QXN3

References