Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2131135..2131736 Replicon chromosome
Accession NZ_AP019373
Organism Sulfuricystis thermophila strain M52

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag M52SOB_RS10750 Protein ID WP_131111805.1
Coordinates 2131135..2131431 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag M52SOB_RS10755 Protein ID WP_131111806.1
Coordinates 2131437..2131736 (+) Length 100 a.a.

Genomic Context

M52SOB_RS10730M52SOB_RS10735M52SOB_RS10740M52SOB_RS10745M52SOB_RS10750M52SOB_RS10755M52SOB_RS10765M52SOB_RS10760M52SOB_RS10770M52SOB_RS10775M52SOB_RS10780
Location: 2126450..2127181 (732 bp)
Type: Others
Protein ID: WP_131111801.1
Location: 2127441..2128964 (1524 bp)
Type: Others
Protein ID: WP_131111802.1
Location: 2128961..2130301 (1341 bp)
Type: Others
Protein ID: WP_131111803.1
Location: 2130337..2130609 (273 bp)
Type: Others
Protein ID: WP_131111804.1
Location: 2131135..2131431 (297 bp)
Type: Toxin
Protein ID: WP_131111805.1
Location: 2131437..2131736 (300 bp)
Type: Antitoxin
Protein ID: WP_131111806.1
Location: 2132569..2133141 (573 bp)
Type: Others
Protein ID: WP_131111807.1
Location: 2131779..2132450 (672 bp)
Type: Others
Protein ID: WP_131112521.1
Location: 2133196..2133597 (402 bp)
Type: Others
Protein ID: WP_172601818.1
Location: 2133603..2133818 (216 bp)
Type: Others
Protein ID: WP_131111809.1
Location: 2133933..2135372 (1440 bp)
Type: Others
Protein ID: WP_284155081.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
M52SOB_RS107302126450..2127181+732WP_131111801.116S rRNA (uracil(1498)-N(3))-methyltransferase-
M52SOB_RS107352127441..2128964+1524WP_131111802.1polyphosphate:AMP phosphotransferase-
M52SOB_RS107402128961..2130301+1341WP_131111803.1amino-acid N-acetyltransferase-
M52SOB_RS107452130337..2130609+273WP_131111804.1oxidative damage protection protein-
M52SOB_RS107502131135..2131431+297WP_131111805.1type II toxin-antitoxin system RelE/ParE family toxinToxin
M52SOB_RS107552131437..2131736+300WP_131111806.1putative addiction module antidote proteinAntitoxin
M52SOB_RS107602131779..2132450-672WP_131112521.1ribose-5-phosphate isomerase RpiA-
M52SOB_RS107652132569..2133141+573WP_131111807.1hypothetical protein-
M52SOB_RS107702133196..2133597-402WP_172601818.1PIN domain-containing protein-
M52SOB_RS107752133603..2133818-216WP_131111809.1hypothetical protein-
M52SOB_RS107802133933..2135372-1440WP_284155081.1dihydrolipoyl dehydrogenase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(50-92)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11021.74 Da        Isoelectric Point: 10.2160

>T32638 WP_131111805.1 NZ_AP019373:2131135-2131431 [Sulfuricystis thermophila]
MIEIRKTDLFAEWLDGLRDIQGRARIQARIERLAAGNPGDVEPVGEGVSELRIDYGPGYRVYFKQRGRKLIILLAGGDKS
TQAKDIKTALRIARNLLE

Download         Length: 297 bp

>T32638 NZ_AP019373:2131135-2131431 [Sulfuricystis thermophila]
ATGATCGAGATTCGGAAGACCGACCTATTTGCCGAGTGGCTCGATGGACTTCGTGATATCCAGGGGAGGGCCCGAATCCA
GGCCAGGATCGAAAGGCTTGCGGCCGGGAATCCTGGCGATGTCGAGCCCGTTGGCGAAGGCGTTTCAGAATTACGTATCG
ACTACGGACCGGGCTACCGGGTGTATTTCAAGCAGCGCGGACGCAAGCTGATCATTTTGTTGGCAGGCGGTGACAAGAGC
ACTCAGGCCAAGGACATCAAAACAGCTTTGCGTATCGCCAGAAACCTTTTGGAGTAG

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10561.07 Da        Isoelectric Point: 6.2230

>AT32638 WP_131111806.1 NZ_AP019373:2131437-2131736 [Sulfuricystis thermophila]
MAKIVTTRYDVAEHLRTPEEMAAYLEACLEEANGDAAFIAKALGDIARAKGMAQVARDAGLSRESLYKALSGERSPSFDT
ILKVISALGLKLHAEASHG

Download         Length: 300 bp

>AT32638 NZ_AP019373:2131437-2131736 [Sulfuricystis thermophila]
ATGGCAAAGATCGTCACCACTCGCTACGACGTTGCAGAACACCTCAGAACGCCTGAAGAAATGGCCGCCTATCTCGAAGC
CTGCCTAGAAGAAGCGAACGGAGATGCGGCCTTTATCGCCAAGGCGCTCGGCGACATCGCTCGCGCAAAAGGAATGGCAC
AGGTTGCCCGCGACGCGGGTCTTTCCCGCGAAAGTCTCTATAAGGCGCTTTCGGGCGAACGTAGCCCGAGCTTCGACACG
ATCCTCAAGGTGATCAGCGCCTTGGGATTGAAATTGCATGCCGAAGCCAGTCACGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References