Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 3987707..3988278 Replicon chromosome
Accession NZ_AP019314
Organism Microcystis viridis NIES-102

Toxin (Protein)


Gene name mazF Uniprot ID A0A3G9JKW3
Locus tag myaer102_RS20495 Protein ID WP_043995641.1
Coordinates 3987946..3988278 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID I4GAK8
Locus tag myaer102_RS20490 Protein ID WP_002772118.1
Coordinates 3987707..3987949 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
myaer102_RS20475 3984396..3985913 + 1518 WP_125731428.1 hypothetical protein -
myaer102_RS20480 3986144..3986806 + 663 WP_002760400.1 potassium channel family protein -
myaer102_RS20485 3986839..3987615 + 777 WP_125731430.1 DUF2092 domain-containing protein -
myaer102_RS20490 3987707..3987949 + 243 WP_002772118.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
myaer102_RS20495 3987946..3988278 + 333 WP_043995641.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
myaer102_RS20500 3988461..3989354 + 894 WP_012263943.1 hypothetical protein -
myaer102_RS20505 3989351..3992413 - 3063 WP_125731432.1 DEAD/DEAH box helicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(6-108)

Antitoxin

SpoVT-AbrB domain

(7-50)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 12588.65 Da        Isoelectric Point: 9.7817

>T32629 WP_043995641.1 NZ_AP019314:3987946-3988278 [Microcystis viridis NIES-102]
VTYIPERGDFLRLSFDPQIGHEQMGNRPALVVSHIDFNRKIGFAFVCPVSNTQRQNPFYVKIPDGEAVTGVIMVDQLRSL
DFRARKASFIGKCPEQLLQDVLRRIKPILF

Download         Length: 333 bp

>T32629 NZ_AP019314:3987946-3988278 [Microcystis viridis NIES-102]
GTGACATACATTCCAGAACGTGGAGATTTCCTGCGGTTGAGCTTCGACCCACAAATTGGGCATGAGCAAATGGGTAATCG
TCCAGCACTGGTGGTAAGCCATATTGATTTTAATCGCAAGATTGGTTTTGCCTTTGTCTGTCCGGTGAGCAATACGCAAC
GCCAGAACCCTTTCTACGTCAAGATTCCAGATGGAGAGGCAGTGACAGGAGTTATCATGGTAGATCAGCTGCGATCGTTG
GACTTCCGAGCGAGAAAAGCGAGCTTTATCGGCAAGTGTCCAGAACAGTTGCTCCAGGATGTTCTCAGAAGAATTAAGCC
GATTCTGTTCTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8942.23 Da        Isoelectric Point: 3.9345

>AT32629 WP_002772118.1 NZ_AP019314:3987707-3987949 [Microcystis viridis NIES-102]
MKSQIGRWGNSLAIRIPKYAVEALNLNPNDVVECSVENGKLVIELIQALPELSLEELLAEVVESPEPEVDWGRPMGEEVW

Download         Length: 243 bp

>AT32629 NZ_AP019314:3987707-3987949 [Microcystis viridis NIES-102]
ATGAAGTCGCAGATTGGACGCTGGGGTAATTCTTTAGCGATTCGGATTCCCAAGTATGCGGTGGAAGCACTAAACCTCAA
TCCCAATGACGTTGTTGAATGTTCTGTGGAAAACGGAAAGCTAGTAATTGAGCTAATTCAAGCCTTGCCTGAGTTAAGCC
TAGAAGAACTACTGGCTGAGGTTGTTGAATCACCGGAGCCGGAAGTGGATTGGGGACGGCCAATGGGAGAGGAGGTTTGG
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G9JKW3

Antitoxin

Source ID Structure
AlphaFold DB I4GAK8

References