Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PumA-relB/upstrm_HI1419-dnstrm_HI1420 |
| Location | 2209073..2209663 | Replicon | chromosome |
| Accession | NZ_AP019314 | ||
| Organism | Microcystis viridis NIES-102 | ||
Toxin (Protein)
| Gene name | PumA | Uniprot ID | I4ID82 |
| Locus tag | myaer102_RS11370 | Protein ID | WP_008201144.1 |
| Coordinates | 2209073..2209363 (+) | Length | 97 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | I4ID81 |
| Locus tag | myaer102_RS11375 | Protein ID | WP_002757266.1 |
| Coordinates | 2209373..2209663 (+) | Length | 97 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| myaer102_RS11335 | 2204342..2204962 | - | 621 | Protein_2116 | agmatinase | - |
| myaer102_RS11345 | 2205359..2205853 | - | 495 | WP_125730771.1 | ATPase | - |
| myaer102_RS11350 | 2206088..2206438 | - | 351 | WP_004162509.1 | DUF86 domain-containing protein | - |
| myaer102_RS11355 | 2206428..2206718 | - | 291 | WP_002757283.1 | nucleotidyltransferase | - |
| myaer102_RS11360 | 2206855..2207352 | - | 498 | WP_012267264.1 | hypothetical protein | - |
| myaer102_RS30675 | 2208283..2208411 | + | 129 | Protein_2121 | PEP-CTERM sorting domain-containing protein | - |
| myaer102_RS30680 | 2208593..2208844 | + | 252 | Protein_2122 | DUF2442 domain-containing protein | - |
| myaer102_RS11370 | 2209073..2209363 | + | 291 | WP_008201144.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| myaer102_RS11375 | 2209373..2209663 | + | 291 | WP_002757266.1 | putative addiction module antidote protein | Antitoxin |
| myaer102_RS11380 | 2209634..2209825 | - | 192 | WP_125730772.1 | hypothetical protein | - |
| myaer102_RS11385 | 2209953..2210753 | + | 801 | WP_008201141.1 | uroporphyrinogen-III C-methyltransferase | - |
| myaer102_RS11390 | 2210764..2211183 | + | 420 | WP_008201139.1 | secondary thiamine-phosphate synthase enzyme YjbQ | - |
| myaer102_RS11395 | 2211316..2211810 | + | 495 | WP_002748906.1 | photosystem I reaction center subunit III | - |
| myaer102_RS11400 | 2211856..2211984 | + | 129 | WP_002738148.1 | photosystem I reaction center subunit IX | - |
| myaer102_RS11405 | 2212151..2213752 | + | 1602 | WP_125732768.1 | carboxylate-amine ligase | - |
| myaer102_RS11410 | 2213883..2214095 | - | 213 | WP_002777112.1 | DUF3148 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 2196052..2209825 | 13773 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 10990.56 Da Isoelectric Point: 9.8618
>T32628 WP_008201144.1 NZ_AP019314:2209073-2209363 [Microcystis viridis NIES-102]
MIEIRQTETYSQWFSNLRDHQAKARIDIRVRRLSMGNPGDVKPVGKGVSELRIDYGPGYRVYFIQRGETLIILLAGGDKQ
TQERDIKTALNLAQDL
MIEIRQTETYSQWFSNLRDHQAKARIDIRVRRLSMGNPGDVKPVGKGVSELRIDYGPGYRVYFIQRGETLIILLAGGDKQ
TQERDIKTALNLAQDL
Download Length: 291 bp
>T32628 NZ_AP019314:2209073-2209363 [Microcystis viridis NIES-102]
ATGATTGAAATTCGCCAGACCGAAACCTACTCTCAGTGGTTTAGCAATTTGCGGGATCACCAAGCAAAAGCACGTATAGA
CATTCGTGTTCGTCGCCTGTCTATGGGCAATCCAGGCGATGTTAAACCAGTAGGAAAAGGTGTATCGGAACTGCGGATCG
ATTATGGCCCAGGCTATCGGGTGTATTTCATTCAGCGAGGCGAGACCTTGATCATCCTCTTGGCAGGAGGAGATAAGCAA
ACTCAAGAACGGGACATCAAAACAGCATTAAATTTAGCACAAGACTTATAG
ATGATTGAAATTCGCCAGACCGAAACCTACTCTCAGTGGTTTAGCAATTTGCGGGATCACCAAGCAAAAGCACGTATAGA
CATTCGTGTTCGTCGCCTGTCTATGGGCAATCCAGGCGATGTTAAACCAGTAGGAAAAGGTGTATCGGAACTGCGGATCG
ATTATGGCCCAGGCTATCGGGTGTATTTCATTCAGCGAGGCGAGACCTTGATCATCCTCTTGGCAGGAGGAGATAAGCAA
ACTCAAGAACGGGACATCAAAACAGCATTAAATTTAGCACAAGACTTATAG
Antitoxin
Download Length: 97 a.a. Molecular weight: 10320.80 Da Isoelectric Point: 4.4475
>AT32628 WP_002757266.1 NZ_AP019314:2209373-2209663 [Microcystis viridis NIES-102]
MATIQTYPWDAAEHLETKEDIAAYLEAALEDGDPSLVVAALGDIARSKGMTHIARETGLGRESLYKALSIEGNPEFATVL
KVLQSLGLRLQVVPIA
MATIQTYPWDAAEHLETKEDIAAYLEAALEDGDPSLVVAALGDIARSKGMTHIARETGLGRESLYKALSIEGNPEFATVL
KVLQSLGLRLQVVPIA
Download Length: 291 bp
>AT32628 NZ_AP019314:2209373-2209663 [Microcystis viridis NIES-102]
ATGGCTACTATCCAAACCTATCCTTGGGATGCGGCAGAACATCTCGAAACAAAAGAAGATATAGCTGCATATCTTGAAGC
AGCTCTTGAAGATGGCGATCCAAGCTTAGTGGTAGCAGCATTAGGTGATATTGCTCGATCTAAAGGGATGACACATATTG
CCCGTGAAACAGGGTTGGGGCGTGAAAGTCTCTATAAAGCTTTGTCAATCGAAGGCAATCCAGAGTTTGCCACAGTTCTT
AAGGTCTTACAATCACTTGGGTTACGCCTCCAAGTCGTACCAATTGCCTAA
ATGGCTACTATCCAAACCTATCCTTGGGATGCGGCAGAACATCTCGAAACAAAAGAAGATATAGCTGCATATCTTGAAGC
AGCTCTTGAAGATGGCGATCCAAGCTTAGTGGTAGCAGCATTAGGTGATATTGCTCGATCTAAAGGGATGACACATATTG
CCCGTGAAACAGGGTTGGGGCGTGAAAGTCTCTATAAAGCTTTGTCAATCGAAGGCAATCCAGAGTTTGCCACAGTTCTT
AAGGTCTTACAATCACTTGGGTTACGCCTCCAAGTCGTACCAATTGCCTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|