Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 668584..669155 Replicon chromosome
Accession NZ_AP019314
Organism Microcystis viridis NIES-102

Toxin (Protein)


Gene name vapC Uniprot ID A0A3G9JC50
Locus tag myaer102_RS03430 Protein ID WP_041804105.1
Coordinates 668584..668925 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID I4I6X1
Locus tag myaer102_RS03435 Protein ID WP_002799619.1
Coordinates 668922..669155 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
myaer102_RS03415 664126..665169 + 1044 WP_125730334.1 IS630 family transposase -
myaer102_RS03420 665285..667021 - 1737 WP_012266015.1 IS1634 family transposase -
myaer102_RS03425 667670..668512 - 843 WP_012266017.1 IS5 family transposase -
myaer102_RS03430 668584..668925 - 342 WP_041804105.1 DUF5615 family PIN-like protein Toxin
myaer102_RS03435 668922..669155 - 234 WP_002799619.1 DUF433 domain-containing protein Antitoxin
myaer102_RS30475 669404..669544 + 141 WP_164516965.1 hypothetical protein -
myaer102_RS03440 669806..670102 - 297 WP_012266020.1 hypothetical protein -
myaer102_RS03445 670665..672149 - 1485 WP_012264152.1 IS1380-like element ISMae9 family transposase -
myaer102_RS03455 672560..672868 - 309 WP_041804106.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 664126..665169 1043
- flank IS/Tn - - 670665..672149 1484


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-78)

Antitoxin

Protein of unknown function DUF433

(11-66)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12506.41 Da        Isoelectric Point: 4.3569

>T32625 WP_041804105.1 NZ_AP019314:c668925-668584 [Microcystis viridis NIES-102]
MKIWIDAQLPPTLANWLSATFGLEASALRDLSLRDAQDINIFEAARAENAVIMTKDSDFIDLVCRLGTPPQILWLTCGNV
TNRNLRQLLSATLPDALEQLRQGTMIVEISNAP

Download         Length: 342 bp

>T32625 NZ_AP019314:c668925-668584 [Microcystis viridis NIES-102]
ATGAAAATTTGGATTGATGCCCAACTACCTCCAACGCTGGCGAACTGGTTATCAGCGACTTTTGGTTTAGAAGCGTCTGC
TCTACGAGACTTGTCCCTTCGAGATGCTCAAGACATCAATATCTTTGAAGCAGCGCGAGCCGAAAATGCCGTGATTATGA
CTAAAGATAGCGACTTCATTGATTTGGTCTGTCGCCTGGGAACACCTCCCCAAATTTTATGGTTGACCTGTGGTAATGTC
ACGAATCGGAATCTGCGGCAATTGCTGTCAGCTACTTTACCTGATGCTTTAGAACAACTACGTCAAGGAACAATGATCGT
AGAGATCAGCAATGCTCCTTAA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8592.99 Da        Isoelectric Point: 4.6320

>AT32625 WP_002799619.1 NZ_AP019314:c669155-668922 [Microcystis viridis NIES-102]
MNSTVSLLTRITQTPGQCGGRPCIRGMRIRVTDILEMLAENVSINEILEDFPDLELADIQACLLFAARRTDFPRLTA

Download         Length: 234 bp

>AT32625 NZ_AP019314:c669155-668922 [Microcystis viridis NIES-102]
ATGAACTCAACAGTTAGCTTGCTTACCCGCATTACTCAAACACCTGGTCAGTGTGGTGGTCGTCCTTGCATCCGAGGGAT
GCGAATTCGAGTGACTGATATTTTAGAAATGTTGGCTGAGAACGTTAGCATTAATGAAATTTTAGAAGACTTCCCCGATT
TGGAACTAGCAGATATCCAAGCTTGTTTGCTTTTTGCAGCTCGCCGTACTGATTTCCCCAGACTAACGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G9JC50

Antitoxin

Source ID Structure
AlphaFold DB I4I6X1

References