Detailed information of TA system TA032620

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-yefM/YoeB-YefM
• Location: 2398655..2399172
• Replicon: chromosome
• Accession: NZ_AP019312
• Organism: Chromobacterium haemolyticum strain CH06-BL

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: GYH29_RS10895
• Protein ID: WP_161523724.1
• Coordinates: 2398918..2399172 (+)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: GYH29_RS10890
• Protein ID: WP_161523723.1
• Coordinates: 2398655..2398918 (+)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GYH29_RS10840	2393763..2394707	+	945	WP_161523713.1	Ig domain-containing protein	-
GYH29_RS10845	2394753..2395082	+	330	WP_161523714.1	hypothetical protein	-
GYH29_RS10850	2395087..2395557	+	471	WP_161523715.1	hypothetical protein	-
GYH29_RS10855	2395559..2395948	+	390	WP_161523716.1	hypothetical protein	-
GYH29_RS10860	2395951..2396337	+	387	WP_161523717.1	HK97 gp10 family phage protein	-
GYH29_RS10865	2396340..2396717	+	378	WP_161523718.1	hypothetical protein	-
GYH29_RS10870	2396779..2397216	+	438	WP_161523719.1	hypothetical protein	-
GYH29_RS10875	2397220..2397681	+	462	WP_161523720.1	hypothetical protein	-
GYH29_RS10880	2397822..2398010	+	189	WP_161523721.1	hypothetical protein	-
GYH29_RS10885	2398160..2398495	+	336	WP_161523722.1	hypothetical protein	-
GYH29_RS10890	2398655..2398918	+	264	WP_161523723.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
GYH29_RS10895	2398918..2399172	+	255	WP_161523724.1	Txe/YoeB family addiction module toxin	Toxin
GYH29_RS10900	2399233..2400810	-	1578	WP_161523725.1	hypothetical protein	-
GYH29_RS10905	2400856..2401146	+	291	WP_161523726.1	phage antirepressor KilAC domain-containing protein	-
GYH29_RS10910	2401366..2401731	+	366	WP_161523727.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2386977..2436684	49707

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (1-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-71)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10247.65 Da
• Isoelectric Point: 8.0612

>T32620 WP_161523724.1 NZ_AP019312:2398918-2399172 [Chromobacterium haemolyticum]
MQIKFDDHAWEDYLYWQQNSKPTLKRINALIKDIQRNPFEGIGKPEPLKHQFAGFWSRRIDDEHRLVYAVQNDVLTILQC
RYHY

Nucleotide

• Length: 255 bp

>T32620 NZ_AP019312:2398918-2399172 [Chromobacterium haemolyticum]
ATGCAGATCAAGTTTGATGACCACGCATGGGAGGACTACCTCTACTGGCAGCAGAACAGCAAGCCCACCCTCAAGCGCAT
CAACGCCCTGATCAAGGACATCCAGCGCAACCCGTTTGAAGGGATAGGCAAGCCGGAGCCATTGAAGCACCAGTTCGCCG
GCTTCTGGTCGCGCCGCATCGATGATGAGCATCGACTCGTCTACGCGGTCCAGAACGATGTGCTGACCATCTTGCAGTGT
CGCTATCACTATTAA

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 9828.99 Da
• Isoelectric Point: 5.1529

>AT32620 WP_161523723.1 NZ_AP019312:2398655-2398918 [Chromobacterium haemolyticum]
MKALTYSHTRQHLAEVMRQVNEDRAPVIVTTQRGEPVVIMSLADYNALEETAYLTRSPENAKRLTDAAARFHSGEAKERT
LLEDEGE

Nucleotide

• Length: 264 bp

>AT32620 NZ_AP019312:2398655-2398918 [Chromobacterium haemolyticum]
TTGAAAGCGCTTACCTACAGCCACACCCGCCAGCACCTGGCCGAAGTCATGCGCCAGGTGAACGAGGACCGGGCGCCGGT
GATCGTCACCACCCAGCGCGGTGAACCGGTGGTGATCATGTCGCTGGCCGATTACAACGCGCTGGAAGAAACCGCCTATC
TGACACGCTCGCCAGAAAACGCCAAGCGTCTGACTGATGCAGCGGCAAGATTTCATAGCGGAGAGGCCAAGGAAAGGACT
CTTCTCGAAGACGAGGGCGAGTGA