Detailed information of TA system TA032617

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafQ-DinJ
• Location: 1855562..1856127
• Replicon: chromosome
• Accession: NZ_AP019309
• Organism: Intestinibaculum porci strain SG0102

Toxin (Protein)

• Gene name: relE
• Uniprot ID: C7H6P5
• Locus tag: SG0102_RS08905
• Protein ID: WP_002596328.1
• Coordinates: 1855837..1856127 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: SG0102_RS08900
• Protein ID: WP_125119618.1
• Coordinates: 1855562..1855840 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SG0102_RS08880	1852090..1853988	+	1899	WP_125119616.1	NAD(+) synthase	-
SG0102_RS08885	1854053..1854502	-	450	WP_125119617.1	maturase	-
SG0102_RS08890	1854674..1854880	-	207	Protein_1717	hypothetical protein	-
SG0102_RS08895	1855040..1855435	-	396	Protein_1718	cysteine-rich VLP domain-containing protein	-
SG0102_RS08900	1855562..1855840	+	279	WP_125119618.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
SG0102_RS08905	1855837..1856127	+	291	WP_002596328.1	type II toxin-antitoxin system YafQ family toxin	Toxin
SG0102_RS08915	1856488..1857292	-	805	Protein_1721	recombinase family protein	-
SG0102_RS08920	1857353..1858225	+	873	WP_157983016.1	hypothetical protein	-
SG0102_RS08925	1858254..1858505	+	252	WP_157983017.1	hypothetical protein	-
SG0102_RS08930	1858818..1860332	-	1515	WP_125119621.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (8-94)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (5-90)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 11112.87 Da
• Isoelectric Point: 8.0630

>T32617 WP_002596328.1 NZ_AP019309:1855837-1856127 [Intestinibaculum porci]
MKETKYTVKYTTSFKKDYKRAIKRGLKIELLEQVVALLAMGEPLPDKNRDHDLSGDWAGHRECHILPDWLLVYRIEDDVL
VLTLARTGTHSDLFGK

Nucleotide

• Length: 291 bp

>T32617 NZ_AP019309:1855837-1856127 [Intestinibaculum porci]
ATGAAAGAAACCAAATATACCGTTAAGTACACGACCAGTTTCAAAAAAGACTACAAACGAGCCATAAAGCGTGGCTTGAA
GATTGAGCTGCTGGAGCAGGTCGTAGCATTGCTGGCAATGGGCGAACCGCTGCCGGATAAGAACCGCGACCATGACCTGT
CCGGCGATTGGGCCGGCCATCGGGAATGTCATATTCTCCCGGACTGGCTGCTTGTCTATCGCATAGAGGATGATGTTCTG
GTGCTGACGCTGGCCCGCACCGGCACACACAGCGACTTGTTCGGCAAATAA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10332.81 Da
• Isoelectric Point: 4.6310

>AT32617 WP_125119618.1 NZ_AP019309:1855562-1855840 [Intestinibaculum porci]
MARNTTNISIRMDADLKAQADALFTELGMNLTTAFNIFVRQSLREGGIPFEIRLEQPNKETVAAMLEAEKIAKDPSVKGY
NDLDELFADLKR

Nucleotide

• Length: 279 bp

>AT32617 NZ_AP019309:1855562-1855840 [Intestinibaculum porci]
ATGGCTAGAAATACCACAAACATCAGTATCCGCATGGACGCAGATTTGAAAGCGCAGGCGGACGCACTGTTTACTGAGCT
TGGCATGAACCTGACTACGGCGTTTAACATCTTTGTGCGCCAGTCGCTTCGTGAAGGTGGCATTCCCTTTGAGATAAGGC
TGGAACAGCCGAACAAAGAAACGGTTGCTGCCATGCTGGAAGCGGAAAAGATTGCAAAAGACCCGTCTGTAAAGGGCTAC
AATGACCTTGACGAGTTGTTTGCTGACCTGAAAAGATGA

Structures

Toxin

• AlphaFold DB: A0A1M4XBM1