Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazF-pemI/MazF(toxin)
Location 6748348..6748982 Replicon chromosome
Accession NZ_AP019308
Organism Paenibacillus baekrokdamisoli strain KCTC 33723

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag EKN16_RS29670 Protein ID WP_125664969.1
Coordinates 6748632..6748982 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag EKN16_RS29665 Protein ID WP_125664967.1
Coordinates 6748348..6748629 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EKN16_RS29650 6743783..6745012 - 1230 WP_125664962.1 beta-glucanase -
EKN16_RS32550 6745041..6745181 + 141 WP_164523050.1 hypothetical protein -
EKN16_RS29655 6745444..6746649 + 1206 WP_125664963.1 DUF4367 domain-containing protein -
EKN16_RS29660 6746920..6748116 + 1197 WP_125664965.1 alanine racemase -
EKN16_RS29665 6748348..6748629 + 282 WP_125664967.1 ribbon-helix-helix protein, CopG family Antitoxin
EKN16_RS29670 6748632..6748982 + 351 WP_125664969.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
EKN16_RS29675 6749210..6749872 + 663 WP_125666789.1 ethanolamine utilization microcompartment protein EutL -
EKN16_RS29680 6749920..6750255 + 336 WP_125666791.1 BMC domain-containing protein -
EKN16_RS29685 6750307..6751830 + 1524 WP_125664971.1 acetaldehyde dehydrogenase (acetylating) -
EKN16_RS29690 6751893..6752180 + 288 WP_125664973.1 BMC domain-containing protein -
EKN16_RS29695 6752189..6752977 + 789 WP_125664975.1 phosphate propanoyltransferase -
EKN16_RS29700 6752984..6753820 + 837 WP_125664977.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-113)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12806.72 Da        Isoelectric Point: 5.1284

>T32616 WP_125664969.1 NZ_AP019308:6748632-6748982 [Paenibacillus baekrokdamisoli]
MIVKRGDVFFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAASHGFDRDSVLLLEQI
RTIDKQRLTDKITHLDDETMRKVDEALQISVGLIDF

Download         Length: 351 bp

>T32616 NZ_AP019308:6748632-6748982 [Paenibacillus baekrokdamisoli]
TTGATCGTTAAACGCGGCGATGTATTTTTTGCTGACTTGTCACCTGTTGTCGGTTCAGAGCAGGGTGGCGTCCGTCCAGT
TCTTGTTATTCAGAATGATATCGGCAATCGCTTCAGTCCAACTGTGATTGTAGCTGCCATAACTGCACAAATTCAGAAGG
CCAAACTGCCGACGCATGTCGAAATTGACGCTGCGTCACACGGGTTTGACCGAGATTCTGTGCTGCTATTGGAGCAGATC
CGAACGATTGATAAACAGCGCTTGACCGATAAGATTACACACCTTGACGATGAGACGATGCGTAAGGTGGATGAGGCGCT
GCAAATCAGCGTTGGCTTAATTGATTTTTAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10607.24 Da        Isoelectric Point: 7.0153

>AT32616 WP_125664967.1 NZ_AP019308:6748348-6748629 [Paenibacillus baekrokdamisoli]
VANLQNTKRIMISLPDHLLEEVDGIVAKENSNRSEFIRQAMKLYLIERKKRQIRESMQRGYLEMAKINLVMASEAFQAEE
DAGDTLGRLVSGV

Download         Length: 282 bp

>AT32616 NZ_AP019308:6748348-6748629 [Paenibacillus baekrokdamisoli]
GTGGCCAATTTGCAAAACACCAAAAGGATAATGATCAGCCTGCCTGATCATTTGCTGGAGGAAGTCGACGGGATCGTTGC
CAAAGAAAACTCAAACCGAAGTGAATTTATTCGTCAGGCGATGAAGTTGTATTTAATCGAGCGTAAAAAGCGCCAAATTC
GCGAATCAATGCAGCGCGGTTATTTGGAAATGGCGAAAATCAACTTGGTGATGGCATCGGAAGCTTTTCAAGCGGAGGAA
GATGCCGGCGATACGCTCGGCCGACTCGTAAGCGGGGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References