Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 1119457..1119998 Replicon chromosome
Accession NZ_AP019307
Organism Nocardioides baekrokdamisoli strain KCTC 39748

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KCTC_RS05340 Protein ID WP_125567448.1
Coordinates 1119457..1119720 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KCTC_RS05345 Protein ID WP_197715257.1
Coordinates 1119717..1119998 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KCTC_RS05315 1114613..1115515 - 903 WP_164512484.1 AraC family transcriptional regulator -
KCTC_RS05320 1115606..1116574 + 969 WP_197715256.1 SLAC1 anion channel family protein -
KCTC_RS05325 1116625..1117062 - 438 WP_125567442.1 hypothetical protein -
KCTC_RS05330 1117062..1117898 - 837 WP_164512485.1 acyltransferase family protein -
KCTC_RS05335 1118054..1119427 + 1374 WP_125567446.1 MFS transporter -
KCTC_RS05340 1119457..1119720 - 264 WP_125567448.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KCTC_RS05345 1119717..1119998 - 282 WP_197715257.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
KCTC_RS05350 1120047..1120544 - 498 WP_125567452.1 DUF1877 family protein -
KCTC_RS05355 1120696..1120980 - 285 WP_125567454.1 HigA family addiction module antidote protein -
KCTC_RS05360 1120993..1121271 - 279 WP_125567456.1 type II toxin-antitoxin system RelE/ParE family toxin -
KCTC_RS05365 1121348..1122754 + 1407 WP_125567458.1 recombinase family protein -
KCTC_RS05370 1123250..1123492 + 243 WP_197715258.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(34-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-67)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 9946.38 Da        Isoelectric Point: 9.8877

>T32613 WP_125567448.1 NZ_AP019307:c1119720-1119457 [Nocardioides baekrokdamisoli]
VTYAISLSPRARRSLSVDLPEAVAAACAQFIFGPLAESPYRVGKPLRDELEGRYSARRGEFRVIYEIHDERVLVRVITVR
HRRDAYS

Download         Length: 264 bp

>T32613 NZ_AP019307:c1119720-1119457 [Nocardioides baekrokdamisoli]
GTGACGTACGCGATCTCCCTGTCGCCGCGAGCGCGGCGCTCGTTGAGCGTCGACCTGCCAGAGGCCGTTGCCGCAGCATG
TGCACAGTTCATCTTCGGGCCGCTGGCCGAAAGTCCGTACCGCGTCGGCAAGCCGTTGCGCGACGAACTGGAAGGCCGCT
ACTCCGCTCGGCGCGGGGAGTTCCGGGTCATCTACGAGATTCATGACGAACGTGTCCTCGTACGCGTCATCACTGTGCGG
CATCGACGTGACGCCTATTCGTGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10149.39 Da        Isoelectric Point: 4.2797

>AT32613 WP_197715257.1 NZ_AP019307:c1119998-1119717 [Nocardioides baekrokdamisoli]
MNTVPLATARAQLSQLVDEAMRTHERVEVTRNGRRAAVILSADDYDSLMETLDILGDAEAMAAIRESEALADDQWIPGDV
VQAELRAAGRLRG

Download         Length: 282 bp

>AT32613 NZ_AP019307:c1119998-1119717 [Nocardioides baekrokdamisoli]
ATGAATACCGTCCCTCTCGCCACTGCACGTGCGCAACTTTCGCAACTTGTTGACGAAGCCATGCGCACCCATGAACGCGT
CGAGGTCACGAGGAACGGTAGGCGCGCAGCGGTCATCCTGAGCGCAGATGACTATGACTCACTCATGGAGACTCTCGACA
TCCTTGGCGACGCCGAGGCGATGGCTGCCATCCGCGAGTCGGAGGCGCTGGCGGACGACCAGTGGATCCCCGGGGATGTG
GTCCAGGCCGAGTTGCGAGCTGCAGGGCGACTGCGCGGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References