32558

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 2595220..2596934 Replicon chromosome
Accession NZ_AP019195
Organism Aeromonas caviae strain GSH8M-1

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag EJL47_RS12240 Protein ID WP_125117290.1
Coordinates 2596281..2596934 (-) Length 218 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag EJL47_RS12235 Protein ID WP_125117289.1
Coordinates 2595220..2596284 (-) Length 355 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJL47_RS12225 2591301..2592014 - 714 WP_125117287.1 M48 family metallopeptidase -
EJL47_RS12230 2592014..2595145 - 3132 WP_125117288.1 HsdR family type I site-specific deoxyribonuclease -
EJL47_RS12235 2595220..2596284 - 1065 WP_125117289.1 macro domain-containing protein Antitoxin
EJL47_RS12240 2596281..2596934 - 654 WP_125117290.1 DUF4433 domain-containing protein Toxin
EJL47_RS12245 2597212..2598570 - 1359 WP_125117291.1 restriction endonuclease subunit S -
EJL47_RS12250 2598567..2599058 - 492 WP_125117292.1 DUF1016 family protein -
EJL47_RS12255 2599055..2601505 - 2451 WP_125117293.1 type I restriction-modification system subunit M -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2571785..2636760 64975


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(17-216)

Antitoxin

Macro domain

(18-131)


Sequences

Toxin        


Download         Length: 218 a.a.        Molecular weight: 25444.06 Da        Isoelectric Point: 7.0176

>T32558 WP_125117290.1 NZ_AP019195:c2596934-2596281 [Aeromonas caviae]
MAYDYSQSLNPQKALIFRIVHRDNLEWILTHGLWAGNGQQQNPHWVHIGLPELIAKRARHPVPLAPYGVLNDYVPFYFTP
FSPMLSNIHSGRGVPRRENDEILILVSSLHRMAELGLPFVFTDSHAYYQWANFYVDLGDLERIDWPLLQRRDFKRDADDL
SKLERYQAEALIHQHCPIEALLGVVCYNEEIKNRVEQCMNRVGVARPVYVRDGWYFR

Download         Length: 654 bp

>T32558 NZ_AP019195:c2596934-2596281 [Aeromonas caviae]
ATGGCCTATGACTATAGCCAGAGCCTGAATCCGCAGAAGGCGCTGATATTCCGGATCGTGCATCGGGATAACCTGGAATG
GATCCTGACCCATGGCCTGTGGGCGGGGAATGGTCAGCAGCAAAACCCGCACTGGGTGCATATCGGGTTGCCGGAGCTGA
TTGCCAAGCGCGCACGCCATCCGGTGCCGCTGGCGCCTTACGGCGTGTTGAATGACTATGTACCCTTCTACTTCACGCCG
TTTTCGCCCATGCTCAGCAATATTCACTCGGGCCGCGGTGTTCCCCGGCGTGAAAATGATGAAATCCTGATCCTGGTTTC
CAGCCTGCATCGCATGGCTGAATTGGGGCTACCGTTTGTGTTTACCGATAGCCATGCCTATTACCAGTGGGCCAATTTCT
ATGTCGATCTTGGCGATCTGGAGCGGATTGACTGGCCACTGTTGCAGCGCCGTGATTTCAAGCGTGATGCGGACGATTTG
AGCAAGCTGGAACGCTATCAGGCCGAGGCCTTGATCCATCAACATTGCCCCATCGAGGCATTGCTGGGTGTGGTGTGTTA
CAACGAAGAGATAAAGAACCGCGTGGAACAATGCATGAATCGGGTGGGGGTCGCGCGCCCCGTCTATGTCCGTGATGGGT
GGTATTTCAGATGA

Antitoxin


Download         Length: 355 a.a.        Molecular weight: 39657.81 Da        Isoelectric Point: 6.8633

>AT32558 WP_125117289.1 NZ_AP019195:c2596284-2595220 [Aeromonas caviae]
MIRYTTGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPANMRAYAEACKQGDVVTGKMFITQTGELLGPRWIVNFPTK
QHWRNPAQMAWIQDGLQDLRAWLQAQQVSSIAIPPLGAGNGGLPWPEVKQAIETALGDLDIDILLYEPSRQYQNVAKRGG
VAELTPARALIAELVRRYWFLGMECSLLEIQKLAWFLARVIGRNPLGDPLQLQFKAHRYGPYANNLTHLLNAMDGSYLQS
DKRIPDSKPFDVIWFNEAKKQELAVYLQTEAKAFLPILEQTTALIDGFESPYGMELLATVDWLIAEEGCAPTLSALREGL
HRWPAGTPWGERKARLFDDRSLQIALTRLQQGLV

Download         Length: 1065 bp

>AT32558 NZ_AP019195:c2596284-2595220 [Aeromonas caviae]
ATGATTCGATATACAACAGGCAATCTGCTGGATGCTCCGGTGGAAGCGCTGGTGAATACCGTCAACACCGTCGGTGTCAT
GGGAAAGGGGATTGCCTTGATGTTCAAAGAGCGGTTCCCGGCCAATATGCGTGCCTATGCCGAGGCGTGCAAGCAGGGTG
ACGTCGTCACCGGCAAGATGTTTATTACCCAGACGGGTGAGCTGCTAGGGCCGCGCTGGATCGTCAACTTTCCGACCAAA
CAGCACTGGCGCAATCCGGCACAGATGGCGTGGATCCAGGACGGTTTGCAGGATCTGCGGGCCTGGTTACAAGCGCAGCA
GGTCTCTTCGATTGCCATTCCACCACTGGGGGCTGGCAACGGTGGTCTGCCTTGGCCGGAGGTCAAACAGGCGATCGAAA
CGGCACTGGGCGATCTGGATATCGATATCCTGCTCTATGAGCCCAGTCGACAATACCAAAATGTGGCCAAGCGCGGCGGG
GTGGCGGAGCTGACTCCGGCTCGGGCCCTGATTGCTGAACTGGTGCGTCGCTACTGGTTTTTAGGGATGGAGTGCAGCTT
GCTGGAGATCCAGAAGCTGGCCTGGTTTCTGGCTCGGGTCATTGGCCGAAACCCGCTGGGGGATCCGTTGCAGTTGCAGT
TTAAGGCCCATCGTTATGGCCCTTATGCCAACAATCTGACTCATCTGCTCAATGCGATGGACGGCAGTTATCTGCAGTCC
GACAAGCGCATTCCGGATAGCAAGCCGTTTGATGTTATCTGGTTTAATGAGGCTAAAAAACAAGAGCTTGCCGTTTATCT
CCAGACCGAGGCCAAAGCATTTTTACCAATACTGGAGCAGACGACCGCGTTAATCGATGGTTTTGAGTCGCCCTATGGCA
TGGAGTTATTGGCCACGGTTGATTGGTTGATCGCCGAAGAGGGCTGTGCGCCGACGCTGAGCGCGTTGCGTGAGGGGTTG
CATCGCTGGCCAGCGGGAACCCCGTGGGGTGAGCGCAAGGCGCGGCTGTTTGATGATCGCAGCCTGCAGATCGCCTTGAC
CCGTTTGCAGCAGGGGTTGGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References