Detailed information of TA system TA032526

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 1852899..1853535
• Replicon: chromosome
• Accession: NZ_AP019011
• Organism: Fluviibacter phosphoraccumulans strain SHINM1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: SHINM1_RS09255
• Protein ID: WP_211148960.1
• Coordinates: 1853155..1853535 (+)
• Length: 127 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: SHINM1_RS09250
• Protein ID: WP_211148959.1
• Coordinates: 1852899..1853150 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SHINM1_RS09235 (SHINM1_018210)	1848509..1849546	-	1038	WP_211148956.1	UDP-glucose 4-epimerase GalE	-
SHINM1_RS09240 (SHINM1_018220)	1849543..1850547	-	1005	WP_211148957.1	DNA damage-inducible protein D	-
SHINM1_RS09245 (SHINM1_018230)	1850840..1852543	+	1704	WP_211148958.1	hypothetical protein	-
SHINM1_RS09250 (SHINM1_018240)	1852899..1853150	+	252	WP_211148959.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
SHINM1_RS09255 (SHINM1_018250)	1853155..1853535	+	381	WP_211148960.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
SHINM1_RS09260 (SHINM1_018270)	1853826..1855172	+	1347	WP_211148961.1	type II toxin-antitoxin system HipA family toxin YjjJ	-
SHINM1_RS09265 (SHINM1_018280)	1855233..1855508	+	276	WP_162049009.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
SHINM1_RS09270 (SHINM1_018290)	1855505..1855846	+	342	WP_211148962.1	type II toxin-antitoxin system RelE/ParE family toxin	-
SHINM1_RS09275 (SHINM1_018300)	1855832..1856881	-	1050	WP_211148963.1	glycosyltransferase family 9 protein	-
SHINM1_RS09280 (SHINM1_018310)	1856881..1857723	-	843	WP_211148964.1	glycosyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-70)

Sequences

Toxin

Protein

• Length: 127 a.a.
• Molecular weight: 13881.39 Da
• Isoelectric Point: 10.0476

>T32526 WP_211148960.1 NZ_AP019011:1853155-1853535 [Fluviibacter phosphoraccumulans]
VAYRLKFLPEALKEWEALDGSIKAPLRAALKKRLENPHVPSAVLGSELAGCYKIKLRKQGYRLVYVVEDDVLVVIVLAIG
IRERLAAYENALKGLVTKRLLGTLGATASVTFKPNFSLTDEAFLQA

Nucleotide

• Length: 381 bp

>T32526 NZ_AP019011:1853155-1853535 [Fluviibacter phosphoraccumulans]
GTGGCTTACCGCCTAAAGTTTCTGCCCGAGGCTTTGAAAGAGTGGGAGGCGCTCGATGGCAGTATCAAAGCGCCTCTCCG
AGCGGCCCTGAAAAAACGGCTGGAGAATCCACACGTCCCGAGTGCGGTGCTTGGATCAGAACTTGCTGGTTGCTACAAAA
TCAAACTTCGCAAGCAAGGGTATCGCCTCGTCTATGTGGTTGAAGATGATGTTCTAGTAGTAATTGTGCTGGCCATCGGC
ATACGAGAGCGGCTGGCTGCTTACGAGAATGCGCTGAAAGGGCTTGTGACGAAGCGCTTACTTGGCACTTTAGGCGCTAC
AGCATCTGTCACATTCAAGCCGAACTTCAGCCTAACTGATGAAGCCTTTCTGCAAGCATGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9480.84 Da
• Isoelectric Point: 5.0481

>AT32526 WP_211148959.1 NZ_AP019011:1852899-1853150 [Fluviibacter phosphoraccumulans]
MDTIYADYSVSMSEFKKNPAQVLRTAGEKPVAVLSHNRPAFYMVTPQLFESLVEELADHDLIDIVRDRLTRKTTAIDVDI
NRI

Nucleotide

• Length: 252 bp

>AT32526 NZ_AP019011:1852899-1853150 [Fluviibacter phosphoraccumulans]
ATGGATACCATTTACGCAGATTACTCAGTGAGCATGTCCGAGTTCAAGAAGAACCCGGCTCAAGTGCTGCGCACCGCAGG
TGAAAAGCCAGTGGCAGTTTTGAGCCATAACCGCCCTGCTTTTTACATGGTGACGCCACAGCTGTTTGAATCTCTGGTTG
AAGAGCTGGCTGATCACGATTTGATCGACATCGTTCGAGATCGCTTAACGCGTAAAACCACAGCCATCGACGTCGACATT
AATAGAATTTAA