Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 1842280..1842811 Replicon chromosome
Accession NZ_AP019011
Organism Fluviibacter phosphoraccumulans strain SHINM1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag SHINM1_RS09195 Protein ID WP_211148948.1
Coordinates 1842280..1842561 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag SHINM1_RS09200 Protein ID WP_211148949.1
Coordinates 1842548..1842811 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SHINM1_RS09175 (SHINM1_018080) 1837316..1838290 - 975 WP_211148944.1 UDP-glucose 4-epimerase GalE -
SHINM1_RS09180 (SHINM1_018090) 1838294..1839727 - 1434 WP_211148945.1 FAD-dependent oxidoreductase -
SHINM1_RS09185 (SHINM1_018100) 1839738..1840712 - 975 WP_211148946.1 SDR family oxidoreductase -
SHINM1_RS09190 (SHINM1_018110) 1840712..1841881 - 1170 WP_211148947.1 nucleotide sugar dehydrogenase -
SHINM1_RS09195 (SHINM1_018130) 1842280..1842561 - 282 WP_211148948.1 type II toxin-antitoxin system YafQ family toxin Toxin
SHINM1_RS09200 (SHINM1_018140) 1842548..1842811 - 264 WP_211148949.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
SHINM1_RS09205 (SHINM1_018150) 1842915..1844204 - 1290 WP_211148950.1 ATP-binding protein -
SHINM1_RS09215 1844649..1844927 - 279 WP_211148952.1 hypothetical protein -
SHINM1_RS09220 1844963..1845328 + 366 WP_211148953.1 hypothetical protein -
SHINM1_RS09225 (SHINM1_018190) 1845722..1846663 + 942 WP_211148954.1 tyrosine-type recombinase/integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-83)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10813.46 Da        Isoelectric Point: 8.0689

>T32525 WP_211148948.1 NZ_AP019011:c1842561-1842280 [Fluviibacter phosphoraccumulans]
MRAIERTGQFKRDYKRESKGIYRSVLDAELVPVLIALASDMPLAERYRDHALTGEWKDHRDCHVKPDLVLIYRKPDDQLL
QLVRLGSHSELGI

Download         Length: 282 bp

>T32525 NZ_AP019011:c1842561-1842280 [Fluviibacter phosphoraccumulans]
ATGCGGGCAATTGAGCGTACCGGTCAGTTTAAGCGAGACTACAAGCGAGAGTCTAAAGGCATCTATAGATCTGTACTAGA
TGCGGAATTGGTGCCGGTTTTAATCGCGCTAGCCTCAGATATGCCATTGGCAGAGCGCTACAGAGATCATGCGCTCACTG
GTGAATGGAAAGATCATCGTGATTGCCATGTGAAACCCGATCTGGTGTTGATCTATCGCAAGCCGGATGATCAGCTCCTC
CAGCTCGTGCGCTTGGGCTCGCACAGCGAGTTAGGTATTTAG

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9557.11 Da        Isoelectric Point: 7.2038

>AT32525 WP_211148949.1 NZ_AP019011:c1842811-1842548 [Fluviibacter phosphoraccumulans]
MTANAVVRARIDEHIKEEASTVLAAMGLTVSDAFRIMLTRVAYEKALPFEPLVPNETTVKAMRDARKAKLARFDSVEALM
ADLHAGN

Download         Length: 264 bp

>AT32525 NZ_AP019011:c1842811-1842548 [Fluviibacter phosphoraccumulans]
ATGACTGCAAACGCTGTCGTTCGGGCGCGCATTGACGAACACATCAAAGAAGAGGCTTCGACCGTTCTCGCGGCGATGGG
GTTAACGGTGTCTGATGCCTTCCGGATTATGTTGACTCGTGTCGCCTATGAAAAGGCGCTGCCTTTTGAGCCTCTGGTGC
CCAATGAAACAACGGTTAAAGCCATGCGGGATGCTCGTAAAGCCAAGCTGGCGCGCTTTGATAGTGTCGAAGCGTTAATG
GCTGACCTGCATGCGGGCAATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References