Detailed information of TA system TA032522

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 1086589..1087108
• Replicon: chromosome
• Accession: NZ_AP019011
• Organism: Fluviibacter phosphoraccumulans strain SHINM1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: SHINM1_RS05415
• Protein ID: WP_162049771.1
• Coordinates: 1086589..1086876 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: SHINM1_RS05420
• Protein ID: WP_162049770.1
• Coordinates: 1086863..1087108 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SHINM1_RS05390 (SHINM1_010600)	1082517..1084676	-	2160	WP_202930688.1	hypothetical protein	-
SHINM1_RS05395 (SHINM1_010610)	1084779..1085126	-	348	WP_162049774.1	transcriptional regulator	-
SHINM1_RS05400 (SHINM1_010620)	1085123..1085494	-	372	WP_202930689.1	DUF6516 family protein	-
SHINM1_RS11635	1085498..1085620	-	123	WP_272482844.1	hypothetical protein	-
SHINM1_RS05405 (SHINM1_010630)	1085741..1086178	-	438	WP_162049773.1	nucleoside deaminase	-
SHINM1_RS05410 (SHINM1_010640)	1086207..1086485	-	279	WP_162049772.1	hypothetical protein	-
SHINM1_RS05415 (SHINM1_010650)	1086589..1086876	-	288	WP_162049771.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
SHINM1_RS05420 (SHINM1_010660)	1086863..1087108	-	246	WP_162049770.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
SHINM1_RS05425 (SHINM1_010670)	1087172..1088620	-	1449	WP_162049769.1	YdiU family protein	-
SHINM1_RS05430 (SHINM1_010680)	1088626..1088883	-	258	WP_162049768.1	hypothetical protein	-
SHINM1_RS05435 (SHINM1_010690)	1089063..1089578	+	516	WP_162049767.1	RNA polymerase-binding protein DksA	-
SHINM1_RS05440 (SHINM1_010700)	1089683..1091797	-	2115	WP_162050918.1	polyribonucleotide nucleotidyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (8-69)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10969.05 Da
• Isoelectric Point: 10.4134

>T32522 WP_162049771.1 NZ_AP019011:c1086876-1086589 [Fluviibacter phosphoraccumulans]
MPTYKLQFHQLALAEWKKLDKTVRDPLIKKLTERLENPRVPAAALIGMPDCYKIKIHSLGYRLVYRVDDGVVYVTVIAVG
KRERSAVYKTALQRL

Nucleotide

• Length: 288 bp

>T32522 NZ_AP019011:c1086876-1086589 [Fluviibacter phosphoraccumulans]
TTGCCGACTTATAAACTACAGTTTCACCAGCTTGCATTAGCAGAATGGAAGAAGCTTGATAAAACGGTACGTGACCCACT
AATCAAAAAGCTAACCGAGCGCTTGGAGAACCCACGTGTGCCGGCAGCGGCACTGATTGGTATGCCCGATTGCTACAAAA
TCAAAATACATTCGCTTGGCTATCGTTTGGTATATCGCGTGGATGATGGTGTGGTCTACGTCACGGTCATCGCTGTTGGC
AAGCGGGAAAGAAGCGCGGTATACAAGACTGCCCTTCAGCGCCTTTAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9118.32 Da
• Isoelectric Point: 4.3176

>AT32522 WP_162049770.1 NZ_AP019011:c1087108-1086863 [Fluviibacter phosphoraccumulans]
MDNILATMSVSVTELKRNYASIIKDADDSPVAVLNHNRPEAYLLPAGHYERLMSYLEDLEDAKLVRERANGPFVEIDLAD
L

Nucleotide

• Length: 246 bp

>AT32522 NZ_AP019011:c1087108-1086863 [Fluviibacter phosphoraccumulans]
ATGGACAACATACTTGCAACAATGAGTGTTAGTGTTACCGAGTTAAAGCGAAATTACGCCTCGATTATCAAAGATGCCGA
TGATAGTCCTGTGGCTGTGCTAAATCATAATCGTCCAGAGGCTTATCTGCTTCCTGCGGGGCATTACGAGCGACTTATGA
GCTATCTCGAAGACTTAGAAGATGCTAAGTTGGTCCGAGAAAGAGCGAACGGGCCATTTGTAGAGATTGATCTTGCCGAC
TTATAA