Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4120708..4121377 Replicon chromosome
Accession NZ_AP019009
Organism Serratia marcescens strain AS-1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag SERAS_RS19715 Protein ID WP_016929976.1
Coordinates 4120708..4121130 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A8G2G4M4
Locus tag SERAS_RS19720 Protein ID WP_004931679.1
Coordinates 4121111..4121377 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SERAS_RS19695 4116594..4117112 + 519 WP_004931683.1 flavodoxin FldB -
SERAS_RS19700 4117150..4118514 - 1365 WP_117287475.1 cell envelope integrity protein CreD -
SERAS_RS19705 4118595..4120013 - 1419 WP_016929974.1 two-component system sensor histidine kinase CreC -
SERAS_RS19710 4120010..4120708 - 699 WP_117287476.1 two-component system response regulator CreB -
SERAS_RS19715 4120708..4121130 - 423 WP_016929976.1 protein YgfX Toxin
SERAS_RS19720 4121111..4121377 - 267 WP_004931679.1 FAD assembly factor SdhE Antitoxin
SERAS_RS19725 4121698..4122690 + 993 WP_049300372.1 tRNA-modifying protein YgfZ -
SERAS_RS19730 4122729..4123226 - 498 WP_079450551.1 DUF2165 domain-containing protein -
SERAS_RS19735 4123377..4124051 - 675 WP_028127690.1 hemolysin III family protein -
SERAS_RS19740 4124235..4124843 + 609 WP_028127691.1 HD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16501.62 Da        Isoelectric Point: 11.2159

>T32508 WP_016929976.1 NZ_AP019009:c4121130-4120708 [Serratia marcescens]
VAQWRCDIRISWRTQLFSLLTHGVLILLILISPWPEGFGPLWLVLLTLVVFQCIRSQKRIAAVQGELRLLADRRFSWHGR
EWRLAKKPWMPGYGMLLTLQPMEGKKRRRLWLASDCMSKEEWRHLRQLLLHPPAGNGEEP

Download         Length: 423 bp

>T32508 NZ_AP019009:c4121130-4120708 [Serratia marcescens]
GTGGCCCAGTGGCGATGTGATATCCGCATTTCCTGGCGCACCCAGCTGTTTTCACTGTTGACCCACGGCGTTCTGATCCT
GCTGATCCTGATTTCGCCCTGGCCGGAGGGCTTTGGCCCGCTCTGGCTGGTGCTGCTGACGCTGGTGGTGTTTCAGTGCA
TTCGTAGCCAGAAGCGCATCGCCGCGGTGCAGGGCGAGCTGCGGCTGCTGGCGGACAGGCGTTTCAGCTGGCACGGCCGC
GAGTGGCGGCTGGCGAAAAAACCGTGGATGCCGGGTTACGGCATGCTGTTGACGCTGCAGCCGATGGAGGGCAAAAAGCG
CCGCCGGCTGTGGCTGGCTTCCGACTGCATGAGCAAAGAGGAGTGGCGCCACCTGCGGCAGCTGTTGCTGCATCCGCCGG
CGGGTAACGGCGAGGAACCCTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10387.89 Da        Isoelectric Point: 4.7921

>AT32508 WP_004931679.1 NZ_AP019009:c4121377-4121111 [Serratia marcescens]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLNDADKALFIRLLECDDPDLFNWLMNHGAPQDGELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT32508 NZ_AP019009:c4121377-4121111 [Serratia marcescens]
ATGGATATTAACAACAAAGCACGTATTCACTGGGCTTGCCGTCGTGGCATGCGCGAGCTGGACATCTCCATCATGCCGTT
CTTCGAATACGAATACGACAGCCTGAATGACGCGGACAAGGCGCTGTTTATCCGCCTGCTGGAGTGTGACGATCCCGATT
TGTTCAACTGGCTGATGAATCATGGCGCGCCGCAGGACGGCGAGCTGCAGAGAATGGTGACCCTGATCCAAACGCGAAAT
AAAGACCGTGGCCCAGTGGCGATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References