Detailed information of TA system TA032491

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): chpSB/PRK09812-ChpS
• Location: 3015432..3016027
• Replicon: chromosome
• Accession: NZ_AP019007
• Organism: Enterobacter oligotrophicus strain CCA6

Toxin (Protein)

• Gene name: chpB
• Uniprot ID: -
• Locus tag: EoCCA6_RS14495
• Protein ID: WP_152083240.1
• Coordinates: 3015677..3016027 (+)
• Length: 117 a.a.

Antitoxin (Protein)

• Gene name: chpS
• Uniprot ID: -
• Locus tag: EoCCA6_RS14490
• Protein ID: WP_152083239.1
• Coordinates: 3015432..3015683 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EoCCA6_RS14480	3011100..3014876	+	3777	WP_152083238.1	autotransporter assembly complex protein TamB	-
EoCCA6_RS14485	3014879..3015223	+	345	WP_014068657.1	gamma-glutamylcyclotransferase	-
EoCCA6_RS14490	3015432..3015683	+	252	WP_152083239.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
EoCCA6_RS14495	3015677..3016027	+	351	WP_152083240.1	type II toxin-antitoxin system ChpB family toxin	Toxin
EoCCA6_RS14500	3016099..3016629	-	531	WP_041911466.1	inorganic diphosphatase	-
EoCCA6_RS14505	3016938..3017894	+	957	WP_152083241.1	galactofuranose ABC transporter substrate-binding protein YtfQ	-
EoCCA6_RS14510	3018020..3019522	+	1503	WP_152083242.1	sugar ABC transporter ATP-binding protein	-
EoCCA6_RS14515	3019533..3020558	+	1026	WP_152083243.1	ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (8-114)

Antitoxin

• Antitoxin PemI-like (1-83)

Sequences

Toxin

Protein

• Length: 117 a.a.
• Molecular weight: 12397.30 Da
• Isoelectric Point: 6.9493

>T32491 WP_152083240.1 NZ_AP019007:3015677-3016027 [Enterobacter oligotrophicus]
MVKRPCFERGDIVLVGFDPASGHEQKGAGRPALVLSVSAFNQLGMTLVAPVTQGGNFARYAGFSVPLSCEEGQSQGIILV
NQIRIMDLNARQAKRIAVASDETVEDVLLRLQAVVS

Nucleotide

• Length: 351 bp

>T32491 NZ_AP019007:3015677-3016027 [Enterobacter oligotrophicus]
ATGGTAAAGCGGCCTTGCTTCGAACGAGGCGACATCGTGTTGGTGGGTTTTGATCCTGCGAGCGGTCATGAGCAAAAGGG
CGCTGGTCGACCGGCGCTCGTGCTGTCTGTTAGTGCGTTCAACCAACTGGGTATGACGCTGGTTGCGCCCGTAACGCAAG
GGGGAAATTTTGCCCGTTATGCAGGCTTCAGCGTGCCGCTGTCATGCGAAGAAGGGCAAAGCCAGGGGATCATCCTTGTG
AACCAAATCCGCATAATGGACTTAAACGCACGTCAGGCAAAGCGAATTGCTGTCGCTTCAGATGAAACAGTTGAGGATGT
ACTGCTTCGGCTACAGGCGGTGGTGAGTTAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9039.42 Da
• Isoelectric Point: 4.6614

>AT32491 WP_152083239.1 NZ_AP019007:3015432-3015683 [Enterobacter oligotrophicus]
MRITIKKWGNSAGMVIPGVVMKELGLKPGQSMEAHVTNHQLVLTPVSKQYSLEELLAQCDMSAPEISEQDVWGCSGPAGD
EVW

Nucleotide

• Length: 252 bp

>AT32491 NZ_AP019007:3015432-3015683 [Enterobacter oligotrophicus]
ATGCGTATAACCATTAAGAAATGGGGCAACAGTGCGGGTATGGTCATTCCTGGTGTGGTAATGAAAGAGCTTGGCCTGAA
GCCAGGCCAGAGTATGGAGGCTCATGTGACGAATCATCAGTTAGTGCTCACTCCGGTGAGCAAACAGTATTCTCTTGAGG
AGTTACTGGCGCAATGCGATATGTCTGCACCTGAGATCAGCGAGCAGGACGTATGGGGATGTTCTGGACCTGCAGGTGAT
GAAGTATGGTAA