Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 3015432..3016027 Replicon chromosome
Accession NZ_AP019007
Organism Enterobacter oligotrophicus strain CCA6

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag EoCCA6_RS14495 Protein ID WP_152083240.1
Coordinates 3015677..3016027 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag EoCCA6_RS14490 Protein ID WP_152083239.1
Coordinates 3015432..3015683 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EoCCA6_RS14480 3011100..3014876 + 3777 WP_152083238.1 autotransporter assembly complex protein TamB -
EoCCA6_RS14485 3014879..3015223 + 345 WP_014068657.1 gamma-glutamylcyclotransferase -
EoCCA6_RS14490 3015432..3015683 + 252 WP_152083239.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
EoCCA6_RS14495 3015677..3016027 + 351 WP_152083240.1 type II toxin-antitoxin system ChpB family toxin Toxin
EoCCA6_RS14500 3016099..3016629 - 531 WP_041911466.1 inorganic diphosphatase -
EoCCA6_RS14505 3016938..3017894 + 957 WP_152083241.1 galactofuranose ABC transporter substrate-binding protein YtfQ -
EoCCA6_RS14510 3018020..3019522 + 1503 WP_152083242.1 sugar ABC transporter ATP-binding protein -
EoCCA6_RS14515 3019533..3020558 + 1026 WP_152083243.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

Antitoxin PemI-like

(1-83)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12397.30 Da        Isoelectric Point: 6.9493

>T32491 WP_152083240.1 NZ_AP019007:3015677-3016027 [Enterobacter oligotrophicus]
MVKRPCFERGDIVLVGFDPASGHEQKGAGRPALVLSVSAFNQLGMTLVAPVTQGGNFARYAGFSVPLSCEEGQSQGIILV
NQIRIMDLNARQAKRIAVASDETVEDVLLRLQAVVS

Download         Length: 351 bp

>T32491 NZ_AP019007:3015677-3016027 [Enterobacter oligotrophicus]
ATGGTAAAGCGGCCTTGCTTCGAACGAGGCGACATCGTGTTGGTGGGTTTTGATCCTGCGAGCGGTCATGAGCAAAAGGG
CGCTGGTCGACCGGCGCTCGTGCTGTCTGTTAGTGCGTTCAACCAACTGGGTATGACGCTGGTTGCGCCCGTAACGCAAG
GGGGAAATTTTGCCCGTTATGCAGGCTTCAGCGTGCCGCTGTCATGCGAAGAAGGGCAAAGCCAGGGGATCATCCTTGTG
AACCAAATCCGCATAATGGACTTAAACGCACGTCAGGCAAAGCGAATTGCTGTCGCTTCAGATGAAACAGTTGAGGATGT
ACTGCTTCGGCTACAGGCGGTGGTGAGTTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9039.42 Da        Isoelectric Point: 4.6614

>AT32491 WP_152083239.1 NZ_AP019007:3015432-3015683 [Enterobacter oligotrophicus]
MRITIKKWGNSAGMVIPGVVMKELGLKPGQSMEAHVTNHQLVLTPVSKQYSLEELLAQCDMSAPEISEQDVWGCSGPAGD
EVW

Download         Length: 252 bp

>AT32491 NZ_AP019007:3015432-3015683 [Enterobacter oligotrophicus]
ATGCGTATAACCATTAAGAAATGGGGCAACAGTGCGGGTATGGTCATTCCTGGTGTGGTAATGAAAGAGCTTGGCCTGAA
GCCAGGCCAGAGTATGGAGGCTCATGTGACGAATCATCAGTTAGTGCTCACTCCGGTGAGCAAACAGTATTCTCTTGAGG
AGTTACTGGCGCAATGCGATATGTCTGCACCTGAGATCAGCGAGCAGGACGTATGGGGATGTTCTGGACCTGCAGGTGAT
GAAGTATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References