Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 729583..730217 Replicon chromosome
Accession NZ_AP018933
Organism Zymobacter palmae strain IAM14233

Toxin (Protein)


Gene name vapC Uniprot ID A0A348HCW0
Locus tag ZBT109_RS03265 Protein ID WP_027705114.1
Coordinates 729810..730217 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A348HCV9
Locus tag ZBT109_RS03260 Protein ID WP_027705113.1
Coordinates 729583..729810 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ZBT109_RS03230 724816..725535 - 720 WP_027705110.1 autoinducer binding domain-containing protein -
ZBT109_RS03235 725876..727540 - 1665 WP_038278159.1 choline dehydrogenase -
ZBT109_RS03250 728250..728489 - 240 WP_038278190.1 hypothetical protein -
ZBT109_RS03255 729016..729300 - 285 WP_038278165.1 hypothetical protein -
ZBT109_RS03260 729583..729810 + 228 WP_027705113.1 antitoxin Antitoxin
ZBT109_RS03265 729810..730217 + 408 WP_027705114.1 tRNA(fMet)-specific endonuclease VapC Toxin
ZBT109_RS03270 730489..730800 + 312 WP_051523786.1 hypothetical protein -
ZBT109_RS03275 730800..731462 + 663 WP_051523787.1 phage portal protein -
ZBT109_RS03280 731809..734184 + 2376 WP_027705115.1 SIR2 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 720311..735356 15045


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15199.54 Da        Isoelectric Point: 7.8251

>T32460 WP_027705114.1 NZ_AP018933:729810-730217 [Zymobacter palmae]
MLKYMLDTNICIFTIKNRPSHIRDLFNLHHGRMCISTVTLMELIYGAEKSACPERNLSVVEGFAARVTVLTYDTLAAEHT
GQLRAEQAKIGRPIGPYDQMVAGHARSLGLIVVTNNRREFDQVPGLRVEDWTQSV

Download         Length: 408 bp

>T32460 NZ_AP018933:729810-730217 [Zymobacter palmae]
ATGCTCAAATACATGCTGGATACCAACATCTGTATTTTTACGATCAAGAACAGACCTTCTCATATACGTGATCTGTTCAA
CCTCCATCATGGCAGAATGTGCATCAGTACAGTCACGCTCATGGAGCTTATCTACGGCGCAGAGAAAAGTGCTTGTCCTG
AACGCAATCTCTCAGTGGTTGAAGGGTTCGCTGCCAGAGTGACGGTGTTGACGTATGACACACTGGCCGCCGAGCATACA
GGGCAATTACGTGCTGAGCAGGCAAAGATAGGTCGCCCTATTGGGCCCTATGATCAAATGGTTGCTGGACATGCGCGCAG
CCTAGGTTTGATTGTGGTCACGAATAATCGGCGCGAGTTCGACCAAGTCCCAGGACTACGCGTGGAAGACTGGACACAAT
CAGTATGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8551.61 Da        Isoelectric Point: 4.7045

>AT32460 WP_027705113.1 NZ_AP018933:729583-729810 [Zymobacter palmae]
MQTTIFKSNRSQAVRLPKAVALPDDVKYVEVIAVGHTRIITPANKVWDEWFDGESIGSDYMADREQPSDQPREVF

Download         Length: 228 bp

>AT32460 NZ_AP018933:729583-729810 [Zymobacter palmae]
ATGCAAACAACGATCTTCAAAAGTAATCGCAGTCAGGCGGTACGGCTGCCTAAAGCTGTGGCTCTTCCTGATGATGTCAA
ATACGTCGAAGTCATCGCAGTAGGCCATACGCGCATCATCACGCCGGCCAACAAGGTCTGGGATGAGTGGTTCGACGGCG
AAAGCATTGGGTCTGACTATATGGCAGATCGTGAGCAGCCATCAGATCAGCCGCGTGAGGTGTTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A348HCW0

Antitoxin

Source ID Structure
AlphaFold DB A0A348HCV9

References