Detailed information of TA system TA032411

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-StbC
• Location: 833062..833735
• Replicon: chromosome
• Accession: NZ_AP018907
• Organism: Blastochloris tepida strain GI

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: BLTE_RS03755
• Protein ID: WP_126397753.1
• Coordinates: 833062..833484 (-)
• Length: 141 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: BLTE_RS03760
• Protein ID: WP_126397755.1
• Coordinates: 833481..833735 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BLTE_RS03725	828128..829171	-	1044	WP_126397745.1	Na+/H+ antiporter NhaA	-
BLTE_RS03730	829365..830231	-	867	WP_126397747.1	transglutaminase family protein	-
BLTE_RS03735	830505..830795	-	291	WP_126397749.1	hypothetical protein	-
BLTE_RS03740	831001..831947	+	947	Protein_735	cold-shock protein	-
BLTE_RS03745	832040..832363	+	324	WP_126397751.1	hypothetical protein	-
BLTE_RS03750	832552..833020	-	469	Protein_737	hypothetical protein	-
BLTE_RS03755	833062..833484	-	423	WP_126397753.1	type II toxin-antitoxin system VapC family toxin	Toxin
BLTE_RS03760	833481..833735	-	255	WP_126397755.1	plasmid stabilization protein	Antitoxin
BLTE_RS03765	833815..834480	-	666	WP_126402031.1	DUF2493 domain-containing protein	-
BLTE_RS03770	834427..834804	+	378	WP_126397756.1	hypothetical protein	-
BLTE_RS03775	835173..835730	-	558	WP_126397758.1	recombinase family protein	-
BLTE_RS03780	836441..836674	+	234	WP_126397760.1	hypothetical protein	-
BLTE_RS03785	836840..837901	+	1062	WP_160140509.1	AAA family ATPase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	812205..842090	29885

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-123)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 141 a.a.
• Molecular weight: 14781.09 Da
• Isoelectric Point: 5.7168

>T32411 WP_126397753.1 NZ_AP018907:c833484-833062 [Blastochloris tepida]
MILLDTNVVSEAMKPEAAPAVRAWLDAQTAETLYLSSVTLAELMFGIGALPKGRRKDKLTAALDGVLELFADRILPFDIR
AARRYAELAVRAHAAGKGGPTPDGYIAAIAAAHDFAVASRDTSAFMAAGLTVIDPWTVAV

Nucleotide

• Length: 423 bp

>T32411 NZ_AP018907:c833484-833062 [Blastochloris tepida]
ATGATCCTGCTCGACACCAACGTCGTCTCCGAGGCGATGAAGCCCGAGGCGGCGCCTGCTGTCCGCGCCTGGCTCGACGC
CCAGACGGCGGAGACGCTCTATCTGTCCAGCGTCACCCTCGCGGAACTGATGTTCGGCATCGGCGCGCTGCCCAAGGGCC
GGCGCAAGGACAAGCTGACCGCCGCGCTCGACGGCGTGCTGGAGTTGTTCGCGGATCGAATCCTGCCGTTCGATATCCGC
GCGGCGCGACGCTATGCCGAACTCGCCGTCCGGGCGCACGCCGCCGGAAAGGGGGGCCCAACGCCCGATGGCTATATCGC
CGCGATCGCCGCCGCGCATGATTTCGCGGTGGCATCGCGCGATACCAGCGCATTTATGGCCGCAGGCCTCACCGTGATCG
ACCCCTGGACCGTTGCCGTCTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9434.79 Da
• Isoelectric Point: 11.1777

>AT32411 WP_126397755.1 NZ_AP018907:c833735-833481 [Blastochloris tepida]
MPAVTIRNLADETHRALKVRAAQNNRSTEAEMRAILDAAVRPQGRLRLGTALAEMSRRIGLTNADVEVLEQRRDTKPAEP
LRFE

Nucleotide

• Length: 255 bp

>AT32411 NZ_AP018907:c833735-833481 [Blastochloris tepida]
ATGCCCGCCGTCACCATTCGCAACCTCGCCGATGAGACGCATCGCGCCTTGAAGGTCCGCGCCGCACAGAACAATCGCAG
CACGGAAGCGGAAATGCGCGCCATCCTGGACGCCGCCGTGCGACCGCAGGGCCGGCTGCGTCTCGGCACCGCGCTGGCGG
AGATGAGCCGGAGGATCGGGCTCACCAATGCCGATGTCGAAGTCCTGGAACAGAGGCGCGACACCAAGCCCGCCGAGCCG
CTGCGGTTCGAATGA