Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 833062..833735 Replicon chromosome
Accession NZ_AP018907
Organism Blastochloris tepida strain GI

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BLTE_RS03755 Protein ID WP_126397753.1
Coordinates 833062..833484 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BLTE_RS03760 Protein ID WP_126397755.1
Coordinates 833481..833735 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BLTE_RS03725 828128..829171 - 1044 WP_126397745.1 Na+/H+ antiporter NhaA -
BLTE_RS03730 829365..830231 - 867 WP_126397747.1 transglutaminase family protein -
BLTE_RS03735 830505..830795 - 291 WP_126397749.1 hypothetical protein -
BLTE_RS03740 831001..831947 + 947 Protein_735 cold-shock protein -
BLTE_RS03745 832040..832363 + 324 WP_126397751.1 hypothetical protein -
BLTE_RS03750 832552..833020 - 469 Protein_737 hypothetical protein -
BLTE_RS03755 833062..833484 - 423 WP_126397753.1 type II toxin-antitoxin system VapC family toxin Toxin
BLTE_RS03760 833481..833735 - 255 WP_126397755.1 plasmid stabilization protein Antitoxin
BLTE_RS03765 833815..834480 - 666 WP_126402031.1 DUF2493 domain-containing protein -
BLTE_RS03770 834427..834804 + 378 WP_126397756.1 hypothetical protein -
BLTE_RS03775 835173..835730 - 558 WP_126397758.1 recombinase family protein -
BLTE_RS03780 836441..836674 + 234 WP_126397760.1 hypothetical protein -
BLTE_RS03785 836840..837901 + 1062 WP_160140509.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 812205..842090 29885


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 14781.09 Da        Isoelectric Point: 5.7168

>T32411 WP_126397753.1 NZ_AP018907:c833484-833062 [Blastochloris tepida]
MILLDTNVVSEAMKPEAAPAVRAWLDAQTAETLYLSSVTLAELMFGIGALPKGRRKDKLTAALDGVLELFADRILPFDIR
AARRYAELAVRAHAAGKGGPTPDGYIAAIAAAHDFAVASRDTSAFMAAGLTVIDPWTVAV

Download         Length: 423 bp

>T32411 NZ_AP018907:c833484-833062 [Blastochloris tepida]
ATGATCCTGCTCGACACCAACGTCGTCTCCGAGGCGATGAAGCCCGAGGCGGCGCCTGCTGTCCGCGCCTGGCTCGACGC
CCAGACGGCGGAGACGCTCTATCTGTCCAGCGTCACCCTCGCGGAACTGATGTTCGGCATCGGCGCGCTGCCCAAGGGCC
GGCGCAAGGACAAGCTGACCGCCGCGCTCGACGGCGTGCTGGAGTTGTTCGCGGATCGAATCCTGCCGTTCGATATCCGC
GCGGCGCGACGCTATGCCGAACTCGCCGTCCGGGCGCACGCCGCCGGAAAGGGGGGCCCAACGCCCGATGGCTATATCGC
CGCGATCGCCGCCGCGCATGATTTCGCGGTGGCATCGCGCGATACCAGCGCATTTATGGCCGCAGGCCTCACCGTGATCG
ACCCCTGGACCGTTGCCGTCTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9434.79 Da        Isoelectric Point: 11.1777

>AT32411 WP_126397755.1 NZ_AP018907:c833735-833481 [Blastochloris tepida]
MPAVTIRNLADETHRALKVRAAQNNRSTEAEMRAILDAAVRPQGRLRLGTALAEMSRRIGLTNADVEVLEQRRDTKPAEP
LRFE

Download         Length: 255 bp

>AT32411 NZ_AP018907:c833735-833481 [Blastochloris tepida]
ATGCCCGCCGTCACCATTCGCAACCTCGCCGATGAGACGCATCGCGCCTTGAAGGTCCGCGCCGCACAGAACAATCGCAG
CACGGAAGCGGAAATGCGCGCCATCCTGGACGCCGCCGTGCGACCGCAGGGCCGGCTGCGTCTCGGCACCGCGCTGGCGG
AGATGAGCCGGAGGATCGGGCTCACCAATGCCGATGTCGAAGTCCTGGAACAGAGGCGCGACACCAAGCCCGCCGAGCCG
CTGCGGTTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References