Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-CC2985
Location 2319820..2320330 Replicon chromosome
Accession NZ_AP018827
Organism Asticcacaulis excentricus strain M6

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag EM6_RS10680 Protein ID WP_126422646.1
Coordinates 2320049..2320330 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag EM6_RS10675 Protein ID WP_172961195.1
Coordinates 2319820..2320062 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EM6_RS10655 2315264..2315677 - 414 WP_126422636.1 flagellar export protein FliJ -
EM6_RS10660 2315690..2317021 - 1332 WP_126422638.1 flagellar protein export ATPase FliI -
EM6_RS10665 2317275..2317715 - 441 WP_126422640.1 type II toxin-antitoxin system PemK/MazF family toxin -
EM6_RS10670 2317819..2319771 + 1953 WP_126422642.1 DUF2075 domain-containing protein -
EM6_RS10675 2319820..2320062 + 243 WP_172961195.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
EM6_RS10680 2320049..2320330 + 282 WP_126422646.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EM6_RS10685 2320330..2321748 + 1419 WP_126422648.1 glycoside hydrolase family 28 protein -
EM6_RS10690 2321910..2323748 + 1839 WP_126422651.1 autotransporter domain-containing protein -
EM6_RS10695 2324253..2324954 + 702 WP_013478129.1 response regulator transcription factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-87)

Antitoxin

Antitoxin ParD

(2-60)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10874.10 Da        Isoelectric Point: 6.2074

>T32410 WP_126422646.1 NZ_AP018827:2320049-2320330 [Asticcacaulis excentricus]
MAVYRLSAAAERKLAEIYAYSLLNFGEAQADDYFYGLHTVFDLLAQNPQMGRSFRQYRRHEHGSHTVFYAQTDYGVLIVQ
IFHHNEDIDSRLD

Download         Length: 282 bp

>T32410 NZ_AP018827:2320049-2320330 [Asticcacaulis excentricus]
ATGGCCGTCTATAGATTATCGGCGGCCGCAGAGCGCAAGCTGGCTGAAATCTATGCCTATTCTCTGCTTAATTTCGGAGA
GGCACAGGCCGATGACTACTTTTATGGCCTGCACACCGTGTTCGATCTCCTGGCGCAGAACCCGCAGATGGGGCGGTCTT
TTCGTCAGTATCGACGCCATGAGCACGGCTCGCACACAGTCTTTTATGCACAGACGGATTACGGTGTCCTGATCGTGCAA
ATCTTTCACCATAACGAAGACATAGACAGCAGGCTGGATTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9198.41 Da        Isoelectric Point: 7.0143

>AT32410 WP_172961195.1 NZ_AP018827:2319820-2320062 [Asticcacaulis excentricus]
MSVSLSETMRGFIKSRVSSGDYHNESEYIRDLVRRDQERLSQELRLTKLLEEAEQSGLSDKSLPDIMQAVKQKLKADGRL

Download         Length: 243 bp

>AT32410 NZ_AP018827:2319820-2320062 [Asticcacaulis excentricus]
ATGAGCGTGTCCCTTTCGGAAACCATGCGCGGTTTTATTAAATCGCGGGTGAGCAGTGGCGACTATCATAATGAGAGCGA
ATATATCCGCGATCTGGTGCGGCGTGATCAGGAGCGCTTGTCTCAGGAACTGCGTCTCACCAAACTTCTGGAAGAGGCCG
AACAAAGTGGCCTGAGTGACAAATCGTTGCCGGACATCATGCAGGCGGTCAAACAAAAGCTGAAGGCCGATGGCCGTCTA
TAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References