Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 3443356..3443825 Replicon chromosome
Accession NZ_AP018817
Organism Sphingomonas bisphenolicum strain AO1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag SBA_RS17120 Protein ID WP_261935289.1
Coordinates 3443550..3443825 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag SBA_RS17115 Protein ID WP_261935288.1
Coordinates 3443356..3443550 (+) Length 65 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SBA_RS17100 (SBA_ch1_33910) 3438415..3439245 + 831 WP_261935286.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
SBA_RS17105 (SBA_ch1_33920) 3439429..3442344 + 2916 WP_224549936.1 excinuclease ABC subunit UvrA -
SBA_RS17110 (SBA_ch1_33930) 3442341..3443192 + 852 WP_261935287.1 serine protease -
SBA_RS17115 (SBA_ch1_33940) 3443356..3443550 + 195 WP_261935288.1 stability determinant Antitoxin
SBA_RS17120 3443550..3443825 + 276 WP_261935289.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SBA_RS17125 (SBA_ch1_33960) 3443845..3444108 + 264 WP_261935290.1 hypothetical protein -
SBA_RS17130 (SBA_ch1_33970) 3444196..3445233 + 1038 WP_261935291.1 hypothetical protein -
SBA_RS17135 (SBA_ch1_33980) 3445582..3445794 + 213 WP_066603914.1 cold-shock protein -
SBA_RS17140 (SBA_ch1_33990) 3445830..3446426 - 597 WP_224548511.1 hypothetical protein -
SBA_RS17145 (SBA_ch1_34000) 3446549..3446752 + 204 WP_261935292.1 hypothetical protein -
SBA_RS17150 (SBA_ch1_34010) 3446940..3447299 + 360 WP_224548509.1 glycine zipper 2TM domain-containing protein -
SBA_RS17155 (SBA_ch1_34020) 3447355..3448287 - 933 WP_261935293.1 FAD-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10487.14 Da        Isoelectric Point: 10.3020

>T32401 WP_261935289.1 NZ_AP018817:3443550-3443825 [Sphingomonas bisphenolicum]
VLPVVWRASALRKLENVIDYIEIRNPAAADRIGAAIRYPADRLSDHPYLHRPGRVPGTREAVVHPNYILVYRVMADRIQI
LALHHSRQQYP

Download         Length: 276 bp

>T32401 NZ_AP018817:3443550-3443825 [Sphingomonas bisphenolicum]
GTGCTGCCGGTCGTCTGGAGAGCCAGCGCTCTACGAAAACTCGAAAACGTCATCGACTATATCGAAATACGGAATCCGGC
GGCGGCCGACCGCATAGGCGCTGCGATCCGGTACCCAGCCGATCGCCTGTCCGACCATCCCTATCTTCACCGTCCCGGCC
GTGTTCCCGGCACGCGAGAGGCTGTGGTTCATCCCAACTATATCCTCGTCTATCGCGTCATGGCCGACCGGATTCAGATA
CTTGCGCTCCACCATAGTCGCCAGCAATATCCCTGA

Antitoxin


Download         Length: 65 a.a.        Molecular weight: 7289.04 Da        Isoelectric Point: 4.1473

>AT32401 WP_261935288.1 NZ_AP018817:3443356-3443550 [Sphingomonas bisphenolicum]
MTKLTPIESEFATTEDAEAYDAWFRAEVEAAMASDEPDIPHDEAMARMQAIIDRRKKADERNTT

Download         Length: 195 bp

>AT32401 NZ_AP018817:3443356-3443550 [Sphingomonas bisphenolicum]
ATGACCAAGCTCACCCCCATCGAGTCCGAGTTCGCGACGACCGAAGACGCGGAAGCCTATGACGCATGGTTCCGTGCGGA
GGTCGAGGCCGCCATGGCATCGGACGAACCCGATATCCCCCATGACGAAGCCATGGCCCGGATGCAGGCCATTATCGACC
GCCGCAAAAAGGCGGACGAGCGCAATACGACATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References