Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2526357..2526591 | Replicon | chromosome |
| Accession | NZ_AP018808 | ||
| Organism | Escherichia coli strain E2865 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2526358..2526461 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2526357..2526591 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EL389_RS13620 | 2523556..2524365 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
| EL389_RS13625 | 2524422..2524616 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| EL389_RS13630 | 2524609..2524797 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 2524615..2524793 | - | 179 | NuclAT_1 | - | - |
| - | 2524615..2524793 | - | 179 | NuclAT_1 | - | - |
| - | 2524615..2524793 | - | 179 | NuclAT_1 | - | - |
| - | 2524615..2524793 | - | 179 | NuclAT_1 | - | - |
| EL389_RS13635 | 2524904..2525185 | + | 282 | WP_001443927.1 | excisionase | - |
| EL389_RS13640 | 2525151..2526266 | + | 1116 | WP_001189092.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 2526357..2526591 | + | 235 | - | - | Antitoxin |
| - | 2526358..2526461 | - | 104 | - | - | Toxin |
| EL389_RS13645 | 2526619..2526960 | - | 342 | WP_000976492.1 | YebY family protein | - |
| EL389_RS13650 | 2526973..2527845 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| EL389_RS13655 | 2527849..2528223 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| EL389_RS13660 | 2528362..2528592 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| EL389_RS13665 | 2528694..2529350 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
| EL389_RS13670 | 2529374..2530036 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleG7' | 2461117..2539568 | 78451 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T32375 NZ_AP018808:c2526461-2526358 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT32375 NZ_AP018808:2526357-2526591 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
