32231

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) VapXD/-
Location 637392..637732 Replicon chromosome
Accession NZ_AP018783
Organism Haemophilus influenzae strain CHBN-V-3 isolate 15H03

Toxin (Protein)


Gene name VapD Uniprot ID A0A806DEN6
Locus tag K6J71_RS03205 Protein ID WP_005652099.1
Coordinates 637595..637732 (+) Length 46 a.a.

Antitoxin (Protein)


Gene name VapX Uniprot ID -
Locus tag K6J71_RS03200 Protein ID WP_221282198.1
Coordinates 637392..637586 (+) Length 65 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6J71_RS09660 (CHBNV3_06060) 633271..633402 - 132 WP_260178610.1 hypothetical protein -
K6J71_RS03180 (CHBNV3_06070) 633602..634585 + 984 WP_005666498.1 DNA polymerase III subunit delta' -
K6J71_RS03185 (CHBNV3_06080) 634640..635422 + 783 WP_005649353.1 YchF/TatD family DNA exonuclease -
K6J71_RS03190 (CHBNV3_06090) 635449..635973 + 525 WP_005649352.1 DUF1523 family protein -
K6J71_RS03195 (CHBNV3_06100) 636024..637322 + 1299 WP_005691371.1 hemolysin family protein -
K6J71_RS03200 (CHBNV3_06110) 637392..637586 + 195 WP_221282198.1 DUF5397 domain-containing protein Antitoxin
K6J71_RS03205 (CHBNV3_06120) 637595..637732 + 138 WP_005652099.1 hypothetical protein Toxin
K6J71_RS03210 (CHBNV3_06130) 637825..638355 + 531 WP_005649345.1 hypothetical protein -
K6J71_RS03215 (CHBNV3_06140) 638427..639926 + 1500 WP_005649342.1 fused PTS fructose transporter subunit IIA/HPr protein -
K6J71_RS03220 (CHBNV3_06150) 639928..640869 + 942 WP_005649339.1 1-phosphofructokinase -
K6J71_RS03225 (CHBNV3_06160) 640871..642541 + 1671 WP_005649337.1 fructose-specific PTS transporter subunit EIIC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Protein of unknown function DUF5397

(4-64)


Sequences

Toxin        


Download         Length: 46 a.a.        Molecular weight: 5256.88 Da        Isoelectric Point: 4.6701

>T32231 WP_005652099.1 NZ_AP018783:637595-637732 [Haemophilus influenzae]
MYAIAFDLVVKGTQDYHPKGVQQAYTDIGAFRIEQWSDFTDFIRN

Download         Length: 138 bp

>T32231 NZ_AP018783:637595-637732 [Haemophilus influenzae]
ATGTACGCGATTGCTTTTGATTTAGTTGTAAAAGGCACTCAAGATTATCATCCAAAGGGCGTTCAACAGGCTTATACAGA
CATTGGTGCTTTTCGTATTGAGCAATGGTCTGATTTTACTGATTTTATACGAAATTAA

Antitoxin


Download         Length: 65 a.a.        Molecular weight: 7215.20 Da        Isoelectric Point: 3.9930

>AT32231 WP_221282198.1 NZ_AP018783:637392-637586 [Haemophilus influenzae]
IWELRQQIPTGCIKQFGQFGVPYVVGEVAEFLPDGDVLVNITLLQSGEKDIYRLSHLLEDPEAE

Download         Length: 195 bp

>AT32231 NZ_AP018783:637392-637586 [Haemophilus influenzae]
ATATGGGAACTAAGACAACAAATTCCAACAGGCTGTATTAAGCAATTTGGGCAATTTGGCGTGCCTTATGTGGTTGGCGA
GGTTGCGGAATTTTTGCCAGATGGTGATGTGTTGGTAAATATCACATTATTACAATCTGGAGAAAAAGACATTTATCGAT
TATCTCACCTGCTTGAAGATCCCGAAGCTGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A806DEN6

Antitoxin

Source ID Structure

References