Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3673218..3673366 Replicon chromosome
Accession NZ_AP018756
Organism Metakosakonia sp. MRY16-398

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3673218..3673320 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3673218..3673366 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MRY16398_RS18045 3668378..3668713 + 336 WP_047369725.1 hypothetical protein -
MRY16398_RS18050 3668717..3669067 + 351 WP_172600638.1 Rrf2 family transcriptional regulator -
MRY16398_RS18055 3669206..3671713 + 2508 WP_125124957.1 exonuclease -
MRY16398_RS18060 3671778..3672050 + 273 WP_107222989.1 excisionase -
MRY16398_RS18065 3672025..3673131 + 1107 WP_125124958.1 phage integrase Arm DNA-binding domain-containing protein -
- 3673218..3673320 - 103 - - Toxin
- 3673218..3673366 + 149 - - Antitoxin
MRY16398_RS18070 3673477..3673818 - 342 WP_107222991.1 YebY family protein -
MRY16398_RS18075 3673833..3674702 - 870 WP_079496722.1 copper homeostasis membrane protein CopD -
MRY16398_RS18080 3674704..3675078 - 375 WP_071195198.1 CopC domain-containing protein YobA -
MRY16398_RS18085 3675216..3675446 + 231 WP_039078743.1 DNA polymerase III subunit theta -
MRY16398_RS18090 3675443..3676120 + 678 WP_125124959.1 exodeoxyribonuclease X -
MRY16398_RS18095 3676117..3678177 - 2061 WP_125124960.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - gtrB / hsiC1/vipB / hsiB1/vipA / flhA / cheZ / cheY / cheB / cheR / cheW / cheA / motB / motA / flhC / flhD 3469494..3787215 317721


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T32073 NZ_AP018756:c3673320-3673218 [Metakosakonia sp. MRY16-398]
GCATGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 149 bp

>AT32073 NZ_AP018756:3673218-3673366 [Metakosakonia sp. MRY16-398]
AAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TAATGCAGGCTAAGTCGCCATGCACTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGGCAAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References