32068

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 965730..966393 Replicon chromosome
Accession NZ_AP018756
Organism Metakosakonia sp. MRY16-398

Toxin (Protein)


Gene name cptA Uniprot ID A0A348D8P9
Locus tag MRY16398_RS04660 Protein ID WP_039077972.1
Coordinates 965977..966393 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A348D8P8
Locus tag MRY16398_RS04655 Protein ID WP_039077973.1
Coordinates 965730..965996 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MRY16398_RS04630 960908..962341 - 1434 WP_079497183.1 6-phospho-beta-glucosidase -
MRY16398_RS04635 962465..963193 - 729 WP_039077977.1 MurR/RpiR family transcriptional regulator -
MRY16398_RS04640 963246..963557 + 312 WP_039077976.1 N(4)-acetylcytidine aminohydrolase -
MRY16398_RS04645 963720..964379 + 660 WP_125123906.1 hemolysin III family protein -
MRY16398_RS04650 964497..965480 - 984 WP_071196007.1 tRNA-modifying protein YgfZ -
MRY16398_RS04655 965730..965996 + 267 WP_039077973.1 FAD assembly factor SdhE Antitoxin
MRY16398_RS04660 965977..966393 + 417 WP_039077972.1 protein YgfX Toxin
MRY16398_RS04665 966396..966917 - 522 WP_125123907.1 flavodoxin FldB -
MRY16398_RS04670 967019..967915 + 897 WP_039077970.1 site-specific tyrosine recombinase XerD -
MRY16398_RS04675 967940..968653 + 714 WP_039077969.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
MRY16398_RS04680 968659..970392 + 1734 WP_125123908.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16438.33 Da        Isoelectric Point: 11.4778

>T32068 WP_039077972.1 NZ_AP018756:965977-966393 [Metakosakonia sp. MRY16-398]
VVLWQSDIRVSWRSQWLSLLLHGLMAAFVLLLPWPLSYTPLWLLLLSLVVFDSVRSQRRINACQGEIKLLMDARLRWQGV
EWEIVGTPWMLNIGMILRLRREKDGRRQHLWLAADSMDAQEWRDLRRLISQQSAQRQH

Download         Length: 417 bp

>T32068 NZ_AP018756:965977-966393 [Metakosakonia sp. MRY16-398]
GTGGTCCTGTGGCAATCTGATATACGCGTCTCATGGCGCTCACAGTGGCTCTCACTTTTACTCCATGGCTTGATGGCGGC
TTTCGTGTTGCTGTTACCCTGGCCATTGAGTTATACGCCGCTTTGGTTACTGCTTTTGTCACTGGTGGTGTTCGACAGCG
TACGGAGTCAGCGCCGCATTAATGCCTGTCAGGGAGAGATCAAACTGTTGATGGATGCACGTTTGCGCTGGCAAGGCGTG
GAGTGGGAAATCGTCGGAACACCATGGATGCTGAATATTGGCATGATTCTGCGTTTGCGTCGGGAAAAAGATGGTCGCCG
ACAGCATCTGTGGCTGGCCGCAGATAGCATGGATGCGCAAGAGTGGCGTGATTTGCGCCGACTGATTTCGCAACAATCGG
CGCAGCGTCAGCACTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10555.03 Da        Isoelectric Point: 6.2199

>AT32068 WP_039077973.1 NZ_AP018756:965730-965996 [Metakosakonia sp. MRY16-398]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDDDKRVFVRLLQSDDPDLFNWLMNHGKPQDEALQRMIQLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT32068 NZ_AP018756:965730-965996 [Metakosakonia sp. MRY16-398]
ATGGATATTAACAACAAAGCCCGTATTCATTGGGCATGTCGGCGCGGAATGCGTGAGCTGGATATTTCCATCATGCCTTT
CTTTGAACATGAATATGATTCGCTGAGTGATGATGACAAACGTGTGTTTGTGCGTCTTCTGCAGAGCGATGACCCTGATT
TATTTAACTGGCTGATGAATCACGGCAAACCTCAGGACGAGGCGTTGCAGCGAATGATCCAGTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A348D8P9

Antitoxin

Source ID Structure
AlphaFold DB A0A348D8P8

References