Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 841149..841930 Replicon chromosome
Accession NZ_AP018756
Organism Metakosakonia sp. MRY16-398

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag MRY16398_RS04030 Protein ID WP_125123871.1
Coordinates 841439..841930 (+) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag MRY16398_RS04025 Protein ID WP_125123870.1
Coordinates 841149..841442 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MRY16398_RS04015 838145..838309 + 165 WP_110295761.1 DUF1778 domain-containing protein -
MRY16398_RS04020 838359..840548 - 2190 WP_125123869.1 TonB-dependent siderophore receptor -
MRY16398_RS04025 841149..841442 + 294 WP_125123870.1 DUF1778 domain-containing protein Antitoxin
MRY16398_RS04030 841439..841930 + 492 WP_125123871.1 GNAT family N-acetyltransferase Toxin
MRY16398_RS04035 841995..842692 + 698 Protein_789 hypothetical protein -
MRY16398_RS04040 842679..843194 - 516 WP_125123872.1 hypothetical protein -
MRY16398_RS04045 843349..844500 + 1152 Protein_791 IS3 family transposase -
MRY16398_RS04050 844920..845834 + 915 WP_125123873.1 ParA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(87-144)

Antitoxin

Vibrio phage ICP1, Orf50

(2-95)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17721.58 Da        Isoelectric Point: 7.2655

>T32067 WP_125123871.1 NZ_AP018756:841439-841930 [Metakosakonia sp. MRY16-398]
MISAPEPLHTGHILTPFCCGMDSMDKWLKQRAMKNQVTGASRTFVCCGSDSNVQAYYSLASSAVTTNTAPGRFRRNMPDP
IPVVVLGRLAVDQSLHGQGVGRALVRDAGLRVIQVAETIGIRGMLVHALSDEAREFYLRVGFEPSPMDPMMLMVTLGDLV
ESI

Download         Length: 492 bp

>T32067 NZ_AP018756:841439-841930 [Metakosakonia sp. MRY16-398]
ATGATCTCTGCTCCAGAACCGCTTCATACCGGGCATATTCTTACCCCGTTCTGTTGCGGCATGGATTCTATGGATAAGTG
GCTCAAACAACGGGCGATGAAAAATCAGGTCACTGGCGCATCGCGTACCTTTGTATGTTGCGGCAGCGATTCTAACGTAC
AGGCGTATTACTCGCTGGCGTCCAGCGCGGTAACGACCAACACCGCCCCCGGTCGCTTTCGTCGCAATATGCCCGATCCG
ATCCCGGTGGTGGTGCTGGGACGTCTGGCTGTGGATCAATCACTGCACGGGCAGGGCGTCGGGCGGGCGCTGGTTCGCGA
CGCCGGGCTGCGGGTTATTCAGGTGGCGGAGACTATCGGCATTCGCGGGATGCTGGTGCACGCCCTGTCGGATGAAGCGC
GGGAGTTTTACCTGCGGGTGGGGTTTGAGCCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGGGGGATTTGGTG
GAGAGTATTTAG

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10931.55 Da        Isoelectric Point: 8.6351

>AT32067 WP_125123870.1 NZ_AP018756:841149-841442 [Metakosakonia sp. MRY16-398]
MPAANSMAMKRETLNLRIRPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIEQRIIMADPQAYEEFLARLDQAPAPN
AALRKTMQTPAPWEQEK

Download         Length: 294 bp

>AT32067 NZ_AP018756:841149-841442 [Metakosakonia sp. MRY16-398]
ATGCCAGCCGCAAACAGTATGGCGATGAAACGCGAAACTCTGAATCTGCGCATCAGGCCCGCCGAGCGTGATCTTATCGA
CCGGGCAGCGAAGGCCAGAGGGAAAAACCGCACTGACTTTGTGCTGGAAGCCGCCCGCGCTGCCGCTGAGGAAGCGTTGA
TTGAGCAACGCATCATTATGGCCGATCCGCAGGCTTATGAGGAGTTTCTGGCTCGTCTAGATCAGGCGCCTGCGCCTAAC
GCTGCACTGCGTAAAACTATGCAGACCCCTGCGCCGTGGGAGCAGGAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References