Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 841149..841930 Replicon chromosome
Accession NZ_AP018756
Organism Metakosakonia sp. MRY16-398

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag MRY16398_RS04030 Protein ID WP_125123871.1
Coordinates 841439..841930 (+) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag MRY16398_RS04025 Protein ID WP_125123870.1
Coordinates 841149..841442 (+) Length 98 a.a.

Genomic Context

MRY16398_RS04015MRY16398_RS04025MRY16398_RS04030MRY16398_RS04035MRY16398_RS04045MRY16398_RS04050MRY16398_RS04020MRY16398_RS04040
Location: 838145..838309 (165 bp)
Type: Others
Protein ID: WP_110295761.1
Location: 841149..841442 (294 bp)
Type: Antitoxin
Protein ID: WP_125123870.1
Location: 841439..841930 (492 bp)
Type: Toxin
Protein ID: WP_125123871.1
Location: 841995..842692 (698 bp)
Type: Others
Protein ID: Protein_789
Location: 843349..844500 (1152 bp)
Type: Others
Protein ID: Protein_791
Location: 844920..845834 (915 bp)
Type: Others
Protein ID: WP_125123873.1
Location: 838359..840548 (2190 bp)
Type: Others
Protein ID: WP_125123869.1
Location: 842679..843194 (516 bp)
Type: Others
Protein ID: WP_125123872.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
MRY16398_RS04015838145..838309+165WP_110295761.1DUF1778 domain-containing protein-
MRY16398_RS04020838359..840548-2190WP_125123869.1TonB-dependent siderophore receptor-
MRY16398_RS04025841149..841442+294WP_125123870.1DUF1778 domain-containing proteinAntitoxin
MRY16398_RS04030841439..841930+492WP_125123871.1GNAT family N-acetyltransferaseToxin
MRY16398_RS04035841995..842692+698Protein_789hypothetical protein-
MRY16398_RS04040842679..843194-516WP_125123872.1hypothetical protein-
MRY16398_RS04045843349..844500+1152Protein_791IS3 family transposase-
MRY16398_RS04050844920..845834+915WP_125123873.1ParA family protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(87-144)

Antitoxin

Vibrio phage ICP1, Orf50

(2-95)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17721.58 Da        Isoelectric Point: 7.2655

>T32067 WP_125123871.1 NZ_AP018756:841439-841930 [Metakosakonia sp. MRY16-398]
MISAPEPLHTGHILTPFCCGMDSMDKWLKQRAMKNQVTGASRTFVCCGSDSNVQAYYSLASSAVTTNTAPGRFRRNMPDP
IPVVVLGRLAVDQSLHGQGVGRALVRDAGLRVIQVAETIGIRGMLVHALSDEAREFYLRVGFEPSPMDPMMLMVTLGDLV
ESI

Download         Length: 492 bp

>T32067 NZ_AP018756:841439-841930 [Metakosakonia sp. MRY16-398]
ATGATCTCTGCTCCAGAACCGCTTCATACCGGGCATATTCTTACCCCGTTCTGTTGCGGCATGGATTCTATGGATAAGTG
GCTCAAACAACGGGCGATGAAAAATCAGGTCACTGGCGCATCGCGTACCTTTGTATGTTGCGGCAGCGATTCTAACGTAC
AGGCGTATTACTCGCTGGCGTCCAGCGCGGTAACGACCAACACCGCCCCCGGTCGCTTTCGTCGCAATATGCCCGATCCG
ATCCCGGTGGTGGTGCTGGGACGTCTGGCTGTGGATCAATCACTGCACGGGCAGGGCGTCGGGCGGGCGCTGGTTCGCGA
CGCCGGGCTGCGGGTTATTCAGGTGGCGGAGACTATCGGCATTCGCGGGATGCTGGTGCACGCCCTGTCGGATGAAGCGC
GGGAGTTTTACCTGCGGGTGGGGTTTGAGCCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGGGGGATTTGGTG
GAGAGTATTTAG

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10931.55 Da        Isoelectric Point: 8.6351

>AT32067 WP_125123870.1 NZ_AP018756:841149-841442 [Metakosakonia sp. MRY16-398]
MPAANSMAMKRETLNLRIRPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIEQRIIMADPQAYEEFLARLDQAPAPN
AALRKTMQTPAPWEQEK

Download         Length: 294 bp

>AT32067 NZ_AP018756:841149-841442 [Metakosakonia sp. MRY16-398]
ATGCCAGCCGCAAACAGTATGGCGATGAAACGCGAAACTCTGAATCTGCGCATCAGGCCCGCCGAGCGTGATCTTATCGA
CCGGGCAGCGAAGGCCAGAGGGAAAAACCGCACTGACTTTGTGCTGGAAGCCGCCCGCGCTGCCGCTGAGGAAGCGTTGA
TTGAGCAACGCATCATTATGGCCGATCCGCAGGCTTATGAGGAGTTTCTGGCTCGTCTAGATCAGGCGCCTGCGCCTAAC
GCTGCACTGCGTAAAACTATGCAGACCCCTGCGCCGTGGGAGCAGGAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References