Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1695979..1696124 Replicon chromosome
Accession NZ_AP018753
Organism Klebsiella pneumoniae strain KP67

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1696015..1696117 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1695979..1696124 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D5075_RS08565 1691109..1693169 + 2061 WP_004151449.1 oligopeptidase B -
D5075_RS08570 1693173..1693832 - 660 WP_043906809.1 exodeoxyribonuclease X -
D5075_RS08575 1693911..1694141 - 231 WP_002911406.1 DNA polymerase III subunit theta -
D5075_RS08580 1694254..1694628 + 375 WP_004151448.1 CopC domain-containing protein YobA -
D5075_RS08585 1694632..1695501 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
D5075_RS08590 1695518..1695856 + 339 WP_002911404.1 YebY family protein -
- 1695979..1696124 - 146 - - Antitoxin
- 1696015..1696117 + 103 - - Toxin
D5075_RS28725 1696493..1696636 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
D5075_RS08600 1696741..1697709 - 969 WP_004151446.1 VirK/YbjX family protein -
D5075_RS08605 1697866..1698519 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
D5075_RS08610 1698516..1698707 - 192 WP_002911395.1 YebW family protein -
D5075_RS08615 1698805..1699044 - 240 WP_002911393.1 YebV family protein -
D5075_RS08620 1699160..1700593 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1622924..1709195 86271


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T32049 NZ_AP018753:1696015-1696117 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT32049 NZ_AP018753:c1696124-1695979 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References