Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1627225..1627370 Replicon chromosome
Accession NZ_AP018747
Organism Klebsiella pneumoniae strain KP33

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1627261..1627363 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1627225..1627370 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D5079_RS08300 1622355..1624415 + 2061 WP_004151449.1 oligopeptidase B -
D5079_RS08305 1624419..1625078 - 660 WP_043906809.1 exodeoxyribonuclease X -
D5079_RS08310 1625157..1625387 - 231 WP_002911406.1 DNA polymerase III subunit theta -
D5079_RS08315 1625500..1625874 + 375 WP_004151448.1 CopC domain-containing protein YobA -
D5079_RS08320 1625878..1626747 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
D5079_RS08325 1626764..1627102 + 339 WP_002911404.1 YebY family protein -
- 1627225..1627370 - 146 - - Antitoxin
- 1627261..1627363 + 103 - - Toxin
D5079_RS28610 1627739..1627882 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
D5079_RS08335 1627987..1628955 - 969 WP_004151446.1 VirK/YbjX family protein -
D5079_RS08340 1629112..1629765 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
D5079_RS08345 1629762..1629953 - 192 WP_002911395.1 YebW family protein -
D5079_RS08350 1630051..1630290 - 240 WP_002911393.1 YebV family protein -
D5079_RS08355 1630406..1631839 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T32011 NZ_AP018747:1627261-1627363 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT32011 NZ_AP018747:c1627370-1627225 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References