Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 2013069..2013592 Replicon chromosome
Accession NZ_AP018738
Organism Ferriphaselus amnicola strain OYT1

Toxin (Protein)


Gene name relE Uniprot ID A0A2Z6GE64
Locus tag OYT1_RS10035 Protein ID WP_062626231.1
Coordinates 2013326..2013592 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A2Z6GD91
Locus tag OYT1_RS10030 Protein ID WP_062626230.1
Coordinates 2013069..2013326 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OYT1_RS10015 2008537..2009430 - 894 WP_062626227.1 recombination-associated protein RdgC -
OYT1_RS10020 2009578..2011950 + 2373 WP_062626228.1 phosphoketolase family protein -
OYT1_RS10025 2011938..2013002 + 1065 WP_062626229.1 acetate kinase -
OYT1_RS10030 2013069..2013326 + 258 WP_062626230.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
OYT1_RS10035 2013326..2013592 + 267 WP_062626231.1 Txe/YoeB family addiction module toxin Toxin
OYT1_RS10045 2014075..2015709 - 1635 WP_062626232.1 glucose-6-phosphate isomerase -
OYT1_RS10050 2015815..2016174 - 360 WP_084611945.1 DUF2934 domain-containing protein -
OYT1_RS10055 2016227..2018407 - 2181 WP_062626233.1 1,4-alpha-glucan branching protein GlgB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10127.57 Da        Isoelectric Point: 6.9744

>T32008 WP_062626231.1 NZ_AP018738:2013326-2013592 [Ferriphaselus amnicola]
MPRLLTFTPSAWGDYLYWQGQDKKTLRRINALLNDTLREPFGGIGKPEPLRGDLSGLWSKRIDDTNRLVYQVTDTELVVI
ACLFHYDG

Download         Length: 267 bp

>T32008 NZ_AP018738:2013326-2013592 [Ferriphaselus amnicola]
ATGCCGCGCCTGCTGACCTTCACCCCTTCCGCGTGGGGTGATTATCTCTATTGGCAGGGGCAGGACAAAAAGACCTTGCG
CCGGATCAATGCGCTGCTAAATGACACCCTCCGCGAACCCTTCGGAGGTATCGGCAAGCCTGAACCGCTGAGAGGTGATT
TATCCGGCTTATGGTCAAAGCGTATCGACGACACCAACCGACTGGTGTATCAAGTAACGGATACCGAGTTAGTGGTGATC
GCGTGCCTCTTTCATTACGACGGCTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9425.55 Da        Isoelectric Point: 5.5656

>AT32008 WP_062626230.1 NZ_AP018738:2013069-2013326 [Ferriphaselus amnicola]
MKVVTYSHARNSLKSVLDSVVQDADVTIISRRDAEGDAVVMSLDSYNSIMETLHLTSNPANAAHLARSIQEYREGRAQPR
ELLPD

Download         Length: 258 bp

>AT32008 NZ_AP018738:2013069-2013326 [Ferriphaselus amnicola]
ATGAAAGTCGTGACCTACTCCCATGCGCGCAATTCGCTGAAATCGGTTTTGGATAGCGTAGTGCAAGATGCCGATGTAAC
CATCATTAGCCGCCGCGATGCCGAAGGCGATGCCGTGGTAATGTCGCTGGACAGTTACAACAGCATCATGGAAACCCTGC
ACCTTACCAGCAACCCAGCCAATGCCGCCCACCTTGCCCGCTCCATTCAAGAATACCGCGAAGGCCGTGCACAACCTCGC
GAACTGTTGCCCGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2Z6GE64

Antitoxin

Source ID Structure
AlphaFold DB A0A2Z6GD91

References