32003

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-AbrB
Location 1372021..1372609 Replicon chromosome
Accession NZ_AP018732
Organism Conexivisphaera calida strain NAS-02

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NAS2_RS07055 Protein ID WP_174448997.1
Coordinates 1372021..1372386 (-) Length 122 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NAS2_RS07060 Protein ID WP_174448998.1
Coordinates 1372370..1372609 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NAS2_RS07030 (NAS2_1409) 1367107..1367970 - 864 WP_174448992.1 RNA ligase family protein -
NAS2_RS07035 (NAS2_1410) 1368370..1369212 + 843 WP_174448993.1 hypothetical protein -
NAS2_RS07040 (NAS2_1411) 1369544..1370554 + 1011 WP_174448994.1 ATP-binding protein -
NAS2_RS07045 (NAS2_1412) 1370717..1371283 + 567 WP_174448995.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
NAS2_RS07050 (NAS2_1413) 1371270..1371926 + 657 WP_174448996.1 hypothetical protein -
NAS2_RS07055 (NAS2_1414) 1372021..1372386 - 366 WP_174448997.1 PIN domain-containing protein Toxin
NAS2_RS07060 (NAS2_1415) 1372370..1372609 - 240 WP_174448998.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
NAS2_RS07065 (NAS2_1416) 1373245..1374057 + 813 WP_232085486.1 MBL fold metallo-hydrolase -
NAS2_RS07070 (NAS2_1417) 1374189..1374665 - 477 WP_174448999.1 hypothetical protein -
NAS2_RS07075 (NAS2_1418) 1374806..1375921 + 1116 WP_174449000.1 ATP-binding protein -
NAS2_RS07080 (NAS2_1420) 1376181..1377245 + 1065 WP_174449001.1 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-119)

Antitoxin

SpoVT-AbrB domain

(4-45)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 14113.28 Da        Isoelectric Point: 5.6991

>T32003 WP_174448997.1 NZ_AP018732:c1372386-1372021 [Conexivisphaera calida]
MEAVVDTNFVIAVIFKDHEHHKEALKEWRGISRAYLPLISLTEMAYFFIKSEVNLEVMDEVLSDPKVEVVVNTADDLRFA
VENRDRIAGYDDFNDFLILSVARRLRLPLLTFDRKLRRKSG

Download         Length: 366 bp

>T32003 NZ_AP018732:c1372386-1372021 [Conexivisphaera calida]
TTGGAAGCGGTAGTTGACACGAATTTCGTGATCGCGGTCATTTTCAAGGATCACGAACACCACAAGGAGGCATTGAAGGA
GTGGAGGGGAATCAGCAGGGCGTATCTCCCTCTGATTTCGTTGACTGAGATGGCATATTTTTTCATAAAGAGTGAGGTGA
ACCTCGAAGTCATGGACGAGGTGTTGAGCGATCCAAAGGTCGAGGTCGTGGTTAATACCGCGGACGATCTCCGCTTCGCG
GTCGAAAATAGGGATAGAATTGCTGGATATGATGACTTCAACGACTTCCTCATCCTCTCGGTGGCCCGTAGGCTGAGGCT
GCCTCTGCTGACTTTCGATAGGAAGCTGAGGAGGAAGAGCGGTTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8715.02 Da        Isoelectric Point: 4.8409

>AT32003 WP_174448998.1 NZ_AP018732:c1372609-1372370 [Conexivisphaera calida]
MEEVKVTRNYQITIPYWARKELGIEIGAKLLVQVEGDKIIISKKTGDIASLGLTLGRKITEEEIDRAIDEAGREIGSGS

Download         Length: 240 bp

>AT32003 NZ_AP018732:c1372609-1372370 [Conexivisphaera calida]
ATGGAAGAGGTTAAGGTGACCAGAAACTATCAGATCACGATACCCTATTGGGCTAGGAAGGAGCTTGGCATAGAAATAGG
GGCCAAACTGCTGGTTCAAGTGGAGGGAGATAAGATAATCATATCCAAGAAGACCGGCGATATAGCATCCCTGGGCCTCA
CTTTAGGTAGAAAGATCACCGAGGAGGAGATAGATCGGGCAATAGACGAGGCTGGAAGAGAGATTGGAAGCGGTAGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References