Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relE-copA/RelE-RHH
Location 2230112..2230634 Replicon chromosome
Accession NZ_AP018724
Organism Sulfurivermis fontis strain JG42

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EP379_RS11310 Protein ID WP_127477907.1
Coordinates 2230112..2230402 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name copA Uniprot ID -
Locus tag EP379_RS11315 Protein ID WP_127477908.1
Coordinates 2230392..2230634 (-) Length 81 a.a.

Genomic Context


EP379_RS11320EP379_RS11325EP379_RS11330EP379_RS11335EP379_RS11340EP379_RS11345EP379_RS11350EP379_RS11275EP379_RS11280EP379_RS11285EP379_RS11290EP379_RS11295EP379_RS11300EP379_RS11305EP379_RS11310EP379_RS11315
Location: 2230743..2230928 (186 bp)
Type: Others
Protein ID: WP_127478906.1
Location: 2231012..2231758 (747 bp)
Type: Others
Protein ID: WP_197722779.1
Location: 2231970..2232962 (993 bp)
Type: Others
Protein ID: WP_127477909.1
Location: 2232975..2233175 (201 bp)
Type: Others
Protein ID: WP_127477910.1
Location: 2233172..2234158 (987 bp)
Type: Others
Protein ID: WP_127477911.1
Location: 2234299..2234823 (525 bp)
Type: Others
Protein ID: WP_127477912.1
Location: 2234820..2235383 (564 bp)
Type: Others
Protein ID: WP_172600457.1
Location: 2225458..2226768 (1311 bp)
Type: Others
Protein ID: WP_127477900.1
Location: 2226820..2227077 (258 bp)
Type: Others
Protein ID: WP_127477901.1
Location: 2227211..2227510 (300 bp)
Type: Others
Protein ID: WP_127477902.1
Location: 2227507..2227977 (471 bp)
Type: Others
Protein ID: WP_197722922.1
Location: 2227974..2228756 (783 bp)
Type: Others
Protein ID: WP_127477904.1
Location: 2228756..2229580 (825 bp)
Type: Others
Protein ID: WP_127477905.1
Location: 2229657..2230106 (450 bp)
Type: Others
Protein ID: WP_172600456.1
Location: 2230112..2230402 (291 bp)
Type: Toxin
Protein ID: WP_127477907.1
Location: 2230392..2230634 (243 bp)
Type: Antitoxin
Protein ID: WP_127477908.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EP379_RS112752225458..2226768-1311WP_127477900.1UDP-N-acetylglucosamine 1-carboxyvinyltransferase-
EP379_RS112802226820..2227077-258WP_127477901.1BolA family transcriptional regulator-
EP379_RS112852227211..2227510-300WP_127477902.1STAS domain-containing protein-
EP379_RS112902227507..2227977-471WP_197722922.1outer membrane lipid asymmetry maintenance protein MlaD-
EP379_RS112952227974..2228756-783WP_127477904.1lipid asymmetry maintenance ABC transporter permease subunit MlaE-
EP379_RS113002228756..2229580-825WP_127477905.1ABC transporter ATP-binding protein-
EP379_RS113052229657..2230106-450WP_172600456.1DUF72 domain-containing protein-
EP379_RS113102230112..2230402-291WP_127477907.1type II toxin-antitoxin system RelE/ParE family toxinToxin
EP379_RS113152230392..2230634-243WP_127477908.1CopG family ribbon-helix-helix proteinAntitoxin
EP379_RS113202230743..2230928+186WP_127478906.1hypothetical protein-
EP379_RS113252231012..2231758+747WP_197722779.1VacJ family lipoprotein-
EP379_RS113302231970..2232962+993WP_127477909.1calcium/sodium antiporter-
EP379_RS113352232975..2233175+201WP_127477910.1heavy-metal-associated domain-containing protein-
EP379_RS113402233172..2234158+987WP_127477911.1KpsF/GutQ family sugar-phosphate isomerase-
EP379_RS113452234299..2234823+525WP_127477912.13-deoxy-manno-octulosonate-8-phosphatase KdsC-
EP379_RS113502234820..2235383+564WP_172600457.1LPS export ABC transporter periplasmic protein LptC-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 97 a.a.        Molecular weight: 11295.21 Da        Isoelectric Point: 11.7506

>T31998 WP_127477907.1 NZ_AP018724:c2230402-2230112 [Sulfurivermis fontis]
MEIRWLRKALGNLEQEASYVAREDPAAARMVVQRIWQAVSLLAENPALGQPGRIHGTRELVINRRRYLIPYRVNPRLQCI
EILRVFHASRKPPQRW

Download         Length: 291 bp

>T31998 NZ_AP018724:c2230402-2230112 [Sulfurivermis fontis]
ATGGAGATTAGATGGCTGCGCAAGGCGCTTGGCAATCTTGAGCAGGAAGCCTCTTACGTTGCCCGCGAGGATCCGGCGGC
TGCGCGCATGGTGGTGCAACGCATTTGGCAGGCGGTCAGCCTGTTGGCGGAGAACCCGGCGCTGGGACAACCCGGTCGCA
TCCACGGTACCCGCGAATTGGTGATCAACCGGAGGCGTTACCTTATCCCCTATCGCGTGAATCCGCGCCTGCAATGCATC
GAAATCCTGCGCGTGTTTCATGCCTCCCGCAAGCCGCCGCAACGCTGGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8955.95 Da        Isoelectric Point: 4.2808

>AT31998 WP_127477908.1 NZ_AP018724:c2230634-2230392 [Sulfurivermis fontis]
MSTTMTVRLEPDLKERLEHLAAATHRSKSFLAAEAIREFVELNEWQIREIQAALQEADAGDFASAEEVNDVLGRWGVNGD

Download         Length: 243 bp

>AT31998 NZ_AP018724:c2230634-2230392 [Sulfurivermis fontis]
ATGTCTACGACGATGACCGTCCGATTGGAACCCGATTTGAAGGAGCGGCTGGAACACTTGGCGGCGGCGACCCACCGTTC
CAAATCGTTTTTGGCCGCCGAAGCGATACGTGAGTTCGTTGAACTGAACGAATGGCAGATCCGGGAGATCCAGGCCGCTT
TGCAGGAGGCGGATGCGGGGGACTTCGCTTCGGCAGAGGAGGTCAATGACGTGCTTGGGCGGTGGGGCGTGAATGGAGAT
TAG

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References