Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relE-copA/RelE-RHH |
Location | 2230112..2230634 | Replicon | chromosome |
Accession | NZ_AP018724 | ||
Organism | Sulfurivermis fontis strain JG42 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | EP379_RS11310 | Protein ID | WP_127477907.1 |
Coordinates | 2230112..2230402 (-) | Length | 97 a.a. |
Antitoxin (Protein)
Gene name | copA | Uniprot ID | - |
Locus tag | EP379_RS11315 | Protein ID | WP_127477908.1 |
Coordinates | 2230392..2230634 (-) | Length | 81 a.a. |
Genomic Context
Location: 2230743..2230928 (186 bp)
Type: Others
Protein ID: WP_127478906.1
Type: Others
Protein ID: WP_127478906.1
Location: 2231012..2231758 (747 bp)
Type: Others
Protein ID: WP_197722779.1
Type: Others
Protein ID: WP_197722779.1
Location: 2231970..2232962 (993 bp)
Type: Others
Protein ID: WP_127477909.1
Type: Others
Protein ID: WP_127477909.1
Location: 2232975..2233175 (201 bp)
Type: Others
Protein ID: WP_127477910.1
Type: Others
Protein ID: WP_127477910.1
Location: 2233172..2234158 (987 bp)
Type: Others
Protein ID: WP_127477911.1
Type: Others
Protein ID: WP_127477911.1
Location: 2234299..2234823 (525 bp)
Type: Others
Protein ID: WP_127477912.1
Type: Others
Protein ID: WP_127477912.1
Location: 2234820..2235383 (564 bp)
Type: Others
Protein ID: WP_172600457.1
Type: Others
Protein ID: WP_172600457.1
Location: 2225458..2226768 (1311 bp)
Type: Others
Protein ID: WP_127477900.1
Type: Others
Protein ID: WP_127477900.1
Location: 2226820..2227077 (258 bp)
Type: Others
Protein ID: WP_127477901.1
Type: Others
Protein ID: WP_127477901.1
Location: 2227211..2227510 (300 bp)
Type: Others
Protein ID: WP_127477902.1
Type: Others
Protein ID: WP_127477902.1
Location: 2227507..2227977 (471 bp)
Type: Others
Protein ID: WP_197722922.1
Type: Others
Protein ID: WP_197722922.1
Location: 2227974..2228756 (783 bp)
Type: Others
Protein ID: WP_127477904.1
Type: Others
Protein ID: WP_127477904.1
Location: 2228756..2229580 (825 bp)
Type: Others
Protein ID: WP_127477905.1
Type: Others
Protein ID: WP_127477905.1
Location: 2229657..2230106 (450 bp)
Type: Others
Protein ID: WP_172600456.1
Type: Others
Protein ID: WP_172600456.1
Location: 2230112..2230402 (291 bp)
Type: Toxin
Protein ID: WP_127477907.1
Type: Toxin
Protein ID: WP_127477907.1
Location: 2230392..2230634 (243 bp)
Type: Antitoxin
Protein ID: WP_127477908.1
Type: Antitoxin
Protein ID: WP_127477908.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EP379_RS11275 | 2225458..2226768 | - | 1311 | WP_127477900.1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | - |
EP379_RS11280 | 2226820..2227077 | - | 258 | WP_127477901.1 | BolA family transcriptional regulator | - |
EP379_RS11285 | 2227211..2227510 | - | 300 | WP_127477902.1 | STAS domain-containing protein | - |
EP379_RS11290 | 2227507..2227977 | - | 471 | WP_197722922.1 | outer membrane lipid asymmetry maintenance protein MlaD | - |
EP379_RS11295 | 2227974..2228756 | - | 783 | WP_127477904.1 | lipid asymmetry maintenance ABC transporter permease subunit MlaE | - |
EP379_RS11300 | 2228756..2229580 | - | 825 | WP_127477905.1 | ABC transporter ATP-binding protein | - |
EP379_RS11305 | 2229657..2230106 | - | 450 | WP_172600456.1 | DUF72 domain-containing protein | - |
EP379_RS11310 | 2230112..2230402 | - | 291 | WP_127477907.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
EP379_RS11315 | 2230392..2230634 | - | 243 | WP_127477908.1 | CopG family ribbon-helix-helix protein | Antitoxin |
EP379_RS11320 | 2230743..2230928 | + | 186 | WP_127478906.1 | hypothetical protein | - |
EP379_RS11325 | 2231012..2231758 | + | 747 | WP_197722779.1 | VacJ family lipoprotein | - |
EP379_RS11330 | 2231970..2232962 | + | 993 | WP_127477909.1 | calcium/sodium antiporter | - |
EP379_RS11335 | 2232975..2233175 | + | 201 | WP_127477910.1 | heavy-metal-associated domain-containing protein | - |
EP379_RS11340 | 2233172..2234158 | + | 987 | WP_127477911.1 | KpsF/GutQ family sugar-phosphate isomerase | - |
EP379_RS11345 | 2234299..2234823 | + | 525 | WP_127477912.1 | 3-deoxy-manno-octulosonate-8-phosphatase KdsC | - |
EP379_RS11350 | 2234820..2235383 | + | 564 | WP_172600457.1 | LPS export ABC transporter periplasmic protein LptC | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 11295.21 Da Isoelectric Point: 11.7506
>T31998 WP_127477907.1 NZ_AP018724:c2230402-2230112 [Sulfurivermis fontis]
MEIRWLRKALGNLEQEASYVAREDPAAARMVVQRIWQAVSLLAENPALGQPGRIHGTRELVINRRRYLIPYRVNPRLQCI
EILRVFHASRKPPQRW
MEIRWLRKALGNLEQEASYVAREDPAAARMVVQRIWQAVSLLAENPALGQPGRIHGTRELVINRRRYLIPYRVNPRLQCI
EILRVFHASRKPPQRW
Download Length: 291 bp
>T31998 NZ_AP018724:c2230402-2230112 [Sulfurivermis fontis]
ATGGAGATTAGATGGCTGCGCAAGGCGCTTGGCAATCTTGAGCAGGAAGCCTCTTACGTTGCCCGCGAGGATCCGGCGGC
TGCGCGCATGGTGGTGCAACGCATTTGGCAGGCGGTCAGCCTGTTGGCGGAGAACCCGGCGCTGGGACAACCCGGTCGCA
TCCACGGTACCCGCGAATTGGTGATCAACCGGAGGCGTTACCTTATCCCCTATCGCGTGAATCCGCGCCTGCAATGCATC
GAAATCCTGCGCGTGTTTCATGCCTCCCGCAAGCCGCCGCAACGCTGGTAA
ATGGAGATTAGATGGCTGCGCAAGGCGCTTGGCAATCTTGAGCAGGAAGCCTCTTACGTTGCCCGCGAGGATCCGGCGGC
TGCGCGCATGGTGGTGCAACGCATTTGGCAGGCGGTCAGCCTGTTGGCGGAGAACCCGGCGCTGGGACAACCCGGTCGCA
TCCACGGTACCCGCGAATTGGTGATCAACCGGAGGCGTTACCTTATCCCCTATCGCGTGAATCCGCGCCTGCAATGCATC
GAAATCCTGCGCGTGTTTCATGCCTCCCGCAAGCCGCCGCAACGCTGGTAA
Antitoxin
Download Length: 81 a.a. Molecular weight: 8955.95 Da Isoelectric Point: 4.2808
>AT31998 WP_127477908.1 NZ_AP018724:c2230634-2230392 [Sulfurivermis fontis]
MSTTMTVRLEPDLKERLEHLAAATHRSKSFLAAEAIREFVELNEWQIREIQAALQEADAGDFASAEEVNDVLGRWGVNGD
MSTTMTVRLEPDLKERLEHLAAATHRSKSFLAAEAIREFVELNEWQIREIQAALQEADAGDFASAEEVNDVLGRWGVNGD
Download Length: 243 bp
>AT31998 NZ_AP018724:c2230634-2230392 [Sulfurivermis fontis]
ATGTCTACGACGATGACCGTCCGATTGGAACCCGATTTGAAGGAGCGGCTGGAACACTTGGCGGCGGCGACCCACCGTTC
CAAATCGTTTTTGGCCGCCGAAGCGATACGTGAGTTCGTTGAACTGAACGAATGGCAGATCCGGGAGATCCAGGCCGCTT
TGCAGGAGGCGGATGCGGGGGACTTCGCTTCGGCAGAGGAGGTCAATGACGTGCTTGGGCGGTGGGGCGTGAATGGAGAT
TAG
ATGTCTACGACGATGACCGTCCGATTGGAACCCGATTTGAAGGAGCGGCTGGAACACTTGGCGGCGGCGACCCACCGTTC
CAAATCGTTTTTGGCCGCCGAAGCGATACGTGAGTTCGTTGAACTGAACGAATGGCAGATCCGGGAGATCCAGGCCGCTT
TGCAGGAGGCGGATGCGGGGGACTTCGCTTCGGCAGAGGAGGTCAATGACGTGCTTGGGCGGTGGGGCGTGAATGGAGAT
TAG