Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 2060684..2061186 Replicon chromosome
Accession NZ_AP018721
Organism Sulfuritortus calidifontis strain J1A

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag EL388_RS10530 Protein ID WP_126463275.1
Coordinates 2060684..2060938 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EL388_RS10535 Protein ID WP_126463277.1
Coordinates 2060935..2061186 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL388_RS10495 2056425..2056700 + 276 WP_126463265.1 AF1514 family protein -
EL388_RS10500 2056890..2057114 + 225 WP_126463266.1 hypothetical protein -
EL388_RS10505 2057593..2058801 + 1209 WP_126463268.1 polysaccharide pyruvyl transferase family protein -
EL388_RS10510 2058924..2059352 + 429 WP_126463270.1 hypothetical protein -
EL388_RS10515 2059538..2059834 + 297 WP_197721779.1 hypothetical protein -
EL388_RS10520 2059831..2060196 + 366 WP_126463271.1 helix-turn-helix domain-containing protein -
EL388_RS10525 2060283..2060639 + 357 WP_126463273.1 hypothetical protein -
EL388_RS10530 2060684..2060938 - 255 WP_126463275.1 Txe/YoeB family addiction module toxin Toxin
EL388_RS10535 2060935..2061186 - 252 WP_126463277.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
EL388_RS10540 2061290..2062729 - 1440 WP_126463279.1 NADH-quinone oxidoreductase subunit NuoN -
EL388_RS10545 2062892..2064379 - 1488 WP_197721780.1 NADH-quinone oxidoreductase subunit M -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10205.70 Da        Isoelectric Point: 6.7263

>T31988 WP_126463275.1 NZ_AP018721:c2060938-2060684 [Sulfuritortus calidifontis]
MKLVFADEAWEDYLYWQIQDKRLLERINKLIQETQREPFAGVGKPEPLKHALSGFWSRRITDEHRMVYRAVDDALEIVQL
RFHY

Download         Length: 255 bp

>T31988 NZ_AP018721:c2060938-2060684 [Sulfuritortus calidifontis]
ATGAAACTGGTCTTCGCCGACGAGGCGTGGGAAGACTATCTCTATTGGCAAATACAGGACAAACGCCTGCTGGAGCGAAT
CAACAAGCTGATCCAGGAGACGCAGCGCGAGCCCTTCGCCGGCGTGGGCAAGCCGGAGCCCTTGAAACATGCGCTGTCCG
GCTTCTGGTCGCGGCGGATTACCGACGAGCATCGCATGGTGTATCGCGCGGTGGACGATGCGCTGGAGATCGTGCAGCTT
CGGTTTCACTACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9093.46 Da        Isoelectric Point: 8.0000

>AT31988 WP_126463277.1 NZ_AP018721:c2061186-2060935 [Sulfuritortus calidifontis]
MDAITYTTVRANLASAMDRVCNDHEALIITRNGQQSVVMLSLEDYKALEETAYLLRTPANAKRLLSAVAQLKAGKGAERK
LAE

Download         Length: 252 bp

>AT31988 NZ_AP018721:c2061186-2060935 [Sulfuritortus calidifontis]
ATGGACGCCATCACCTACACCACCGTTAGAGCAAACCTCGCCAGCGCAATGGACCGGGTTTGCAACGACCACGAGGCCTT
GATCATCACCCGCAACGGCCAACAGTCGGTGGTCATGCTCTCGCTCGAAGACTACAAGGCGCTAGAAGAAACCGCCTATC
TGCTGCGCACGCCGGCCAACGCCAAGCGGCTGCTCTCGGCAGTGGCGCAACTCAAAGCCGGCAAAGGCGCCGAGCGGAAA
CTAGCCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References