Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK-MazE
Location 795055..795587 Replicon chromosome
Accession NZ_AP018721
Organism Sulfuritortus calidifontis strain J1A

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag EL388_RS04275 Protein ID WP_126460125.1
Coordinates 795055..795378 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag EL388_RS04280 Protein ID WP_126460128.1
Coordinates 795375..795587 (-) Length 71 a.a.

Genomic Context

EL388_RS04250EL388_RS04255EL388_RS04260EL388_RS04265EL388_RS13810EL388_RS04270EL388_RS04275EL388_RS04280EL388_RS04290EL388_RS04295EL388_RS04300EL388_RS04305EL388_RS04310EL388_RS04315
Location: 792112..792570 (459 bp)
Type: Others
Protein ID: WP_126460113.1
Location: 792908..793159 (252 bp)
Type: Others
Protein ID: WP_126460116.1
Location: 793156..793578 (423 bp)
Type: Others
Protein ID: WP_126460119.1
Location: 793648..794105 (458 bp)
Type: Others
Protein ID: Protein_835
Location: 794588..794755 (168 bp)
Type: Others
Protein ID: WP_165919155.1
Location: 794752..794985 (234 bp)
Type: Others
Protein ID: WP_126460122.1
Location: 795055..795378 (324 bp)
Type: Toxin
Protein ID: WP_126460125.1
Location: 795375..795587 (213 bp)
Type: Antitoxin
Protein ID: WP_126460128.1
Location: 796213..796560 (348 bp)
Type: Others
Protein ID: WP_165919154.1
Location: 796566..796859 (294 bp)
Type: Others
Protein ID: WP_126460134.1
Location: 796964..797194 (231 bp)
Type: Others
Protein ID: WP_126463995.1
Location: 797216..797497 (282 bp)
Type: Others
Protein ID: WP_126460138.1
Location: 797681..799297 (1617 bp)
Type: Others
Protein ID: WP_126460141.1
Location: 799432..800283 (852 bp)
Type: Others
Protein ID: WP_126460144.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EL388_RS04250792112..792570+459WP_126460113.1CopD family protein-
EL388_RS04255792908..793159+252WP_126460116.1type II toxin-antitoxin system Phd/YefM family antitoxin-
EL388_RS04260793156..793578+423WP_126460119.1type II toxin-antitoxin system VapC family toxin-
EL388_RS04265793648..794105+458Protein_835CopD family protein-
EL388_RS13810794588..794755-168WP_165919155.1hypothetical protein-
EL388_RS04270794752..794985-234WP_126460122.1addiction module protein-
EL388_RS04275795055..795378-324WP_126460125.1type II toxin-antitoxin system PemK/MazF family toxinToxin
EL388_RS04280795375..795587-213WP_126460128.1antitoxin MazE family proteinAntitoxin
EL388_RS04290796213..796560-348WP_165919154.1MarR family transcriptional regulator-
EL388_RS04295796566..796859-294WP_126460134.1hypothetical protein-
EL388_RS04300796964..797194-231WP_126463995.1GIY-YIG nuclease family protein-
EL388_RS04305797216..797497-282WP_126460138.1type II toxin-antitoxin system HicA family toxin-
EL388_RS04310797681..799297-1617WP_126460141.1peptide chain release factor 3-
EL388_RS04315799432..800283-852WP_126460144.1GGDEF domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--783461..79685913398


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-105)

Antitoxin

Antitoxin MazE-like

(7-69)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 11570.42 Da        Isoelectric Point: 6.4639

>T31986 WP_126460125.1 NZ_AP018721:c795378-795055 [Sulfuritortus calidifontis]
VRRGDLVTVALQGDLGKPRPALVIQSDLFDAHPSVTILPVTSELRDAPLFRIALAPSDENGLSKPSQIMVDKPQSITREK
IGKVIGHLDDETMLAVNRALAVFLGFT

Download         Length: 324 bp

>T31986 NZ_AP018721:c795378-795055 [Sulfuritortus calidifontis]
GTGAGGCGTGGTGATCTGGTCACGGTCGCCTTGCAAGGCGACCTGGGCAAACCACGCCCCGCCCTCGTCATCCAGTCCGA
TCTGTTCGACGCCCACCCATCCGTCACCATCCTGCCGGTCACCAGCGAACTACGCGATGCACCCTTGTTTCGCATTGCGC
TCGCACCCAGCGACGAAAACGGGCTGAGCAAACCTTCTCAGATCATGGTGGACAAACCGCAATCCATCACACGCGAGAAA
ATCGGCAAGGTCATCGGCCACCTGGATGATGAAACCATGCTGGCAGTCAATCGCGCCCTGGCAGTTTTCCTGGGCTTTAC
TTGA

Antitoxin


Download         Length: 71 a.a.        Molecular weight: 8101.95 Da        Isoelectric Point: 5.0892

>AT31986 WP_126460128.1 NZ_AP018721:c795587-795375 [Sulfuritortus calidifontis]
MATSTSERVQKHRDALRAAGLRPLQIWVPDTRRPGFAEECRRQSLALQDDAHEQETLEWLETAGDREGWQ

Download         Length: 213 bp

>AT31986 NZ_AP018721:c795587-795375 [Sulfuritortus calidifontis]
ATGGCCACCAGCACATCCGAACGGGTGCAAAAGCACCGCGACGCGCTGCGCGCAGCCGGGCTGCGCCCCTTGCAGATTTG
GGTGCCCGATACCCGCCGCCCCGGCTTTGCCGAAGAATGCCGCCGGCAATCGCTGGCCTTACAAGACGATGCGCACGAAC
AGGAAACACTGGAATGGCTTGAAACCGCCGGCGACCGCGAGGGCTGGCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References