Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 792908..793578 Replicon chromosome
Accession NZ_AP018721
Organism Sulfuritortus calidifontis strain J1A

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EL388_RS04260 Protein ID WP_126460119.1
Coordinates 793156..793578 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EL388_RS04255 Protein ID WP_126460116.1
Coordinates 792908..793159 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL388_RS04245 789139..792000 - 2862 WP_126460110.1 DEAD/DEAH box helicase family protein -
EL388_RS04250 792112..792570 + 459 WP_126460113.1 CopD family protein -
EL388_RS04255 792908..793159 + 252 WP_126460116.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
EL388_RS04260 793156..793578 + 423 WP_126460119.1 type II toxin-antitoxin system VapC family toxin Toxin
EL388_RS04265 793648..794105 + 458 Protein_835 CopD family protein -
EL388_RS13810 794588..794755 - 168 WP_165919155.1 hypothetical protein -
EL388_RS04270 794752..794985 - 234 WP_126460122.1 addiction module protein -
EL388_RS04275 795055..795378 - 324 WP_126460125.1 type II toxin-antitoxin system PemK/MazF family toxin -
EL388_RS04280 795375..795587 - 213 WP_126460128.1 antitoxin MazE family protein -
EL388_RS04290 796213..796560 - 348 WP_165919154.1 MarR family transcriptional regulator -
EL388_RS04295 796566..796859 - 294 WP_126460134.1 hypothetical protein -
EL388_RS04300 796964..797194 - 231 WP_126463995.1 GIY-YIG nuclease family protein -
EL388_RS04305 797216..797497 - 282 WP_126460138.1 type II toxin-antitoxin system HicA family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 783461..796859 13398


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(4-64)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15608.08 Da        Isoelectric Point: 5.1354

>T31985 WP_126460119.1 NZ_AP018721:793156-793578 [Sulfuritortus calidifontis]
MSWLLDTCALSEYAKREPAQQVIAWLDEQDEASLYLSVITIGEIEKGILKLRVTDPRRSQKLTAWLGKVEQRFAGRILPL
DAAALHVWAQIASQAELAGQPLPVMDGLLVATAQCHGLTIVTRNVQDFTLYPQVLNPWTL

Download         Length: 423 bp

>T31985 NZ_AP018721:793156-793578 [Sulfuritortus calidifontis]
ATGAGCTGGTTGCTCGACACCTGCGCGCTTTCCGAGTATGCAAAACGAGAGCCCGCACAGCAGGTTATCGCCTGGCTGGA
CGAGCAGGACGAGGCCAGCCTTTATCTCAGCGTGATTACCATAGGTGAAATCGAAAAAGGCATCCTTAAGCTGCGTGTCA
CCGACCCGCGCCGCAGCCAGAAGCTCACCGCCTGGCTGGGCAAGGTGGAACAACGCTTCGCCGGGCGCATCCTGCCGCTC
GATGCCGCGGCGCTGCATGTGTGGGCGCAGATCGCCTCACAAGCGGAACTGGCGGGACAGCCGTTGCCGGTGATGGATGG
CCTGCTTGTGGCTACCGCGCAATGCCACGGCCTCACCATCGTCACGCGCAACGTGCAGGACTTCACCCTCTACCCGCAGG
TGCTCAATCCCTGGACGTTGTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9156.40 Da        Isoelectric Point: 9.8634

>AT31985 WP_126460116.1 NZ_AP018721:792908-793159 [Sulfuritortus calidifontis]
MHSEWQLQEAKSNFSQLVKRAAGGDAQVVTVHGKPTAVVVSAEAYARLTRRKGKLSDALLHPELGIEDLDLARSRDTGRK
FEL

Download         Length: 252 bp

>AT31985 NZ_AP018721:792908-793159 [Sulfuritortus calidifontis]
ATGCACAGCGAATGGCAATTGCAGGAAGCGAAAAGCAACTTCAGTCAACTCGTGAAGCGGGCGGCGGGCGGCGACGCGCA
AGTGGTCACCGTGCACGGCAAGCCCACGGCGGTGGTGGTGTCGGCCGAGGCATATGCCCGCCTCACGCGCCGCAAAGGCA
AGCTTTCCGATGCCCTGCTGCACCCCGAGCTCGGCATCGAAGACCTCGACCTGGCCCGCAGTCGCGATACCGGGCGCAAG
TTTGAGCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References