Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | mazEF/PemK-PrlF |
| Location | 1729617..1730175 | Replicon | chromosome |
| Accession | NZ_AP018718 | ||
| Organism | Sulfuricystis multivorans strain J5B | ||
Toxin (Protein)
| Gene name | mazF | Uniprot ID | - |
| Locus tag | EL335_RS08610 | Protein ID | WP_126445976.1 |
| Coordinates | 1729617..1729955 (-) | Length | 113 a.a. |
Antitoxin (Protein)
| Gene name | mazE | Uniprot ID | - |
| Locus tag | EL335_RS08615 | Protein ID | WP_126445978.1 |
| Coordinates | 1729945..1730175 (-) | Length | 77 a.a. |
Genomic Context
Location: 1730265..1731302 (1038 bp)
Type: Others
Protein ID: WP_126445980.1
Type: Others
Protein ID: WP_126445980.1
Location: 1733756..1733998 (243 bp)
Type: Others
Protein ID: WP_126445989.1
Type: Others
Protein ID: WP_126445989.1
Location: 1733995..1734882 (888 bp)
Type: Others
Protein ID: WP_126445991.1
Type: Others
Protein ID: WP_126445991.1
Location: 1726747..1727682 (936 bp)
Type: Others
Protein ID: WP_126445972.1
Type: Others
Protein ID: WP_126445972.1
Location: 1727715..1728911 (1197 bp)
Type: Others
Protein ID: WP_284155499.1
Type: Others
Protein ID: WP_284155499.1
Location: 1728923..1729624 (702 bp)
Type: Others
Protein ID: WP_284155300.1
Type: Others
Protein ID: WP_284155300.1
Location: 1729617..1729955 (339 bp)
Type: Toxin
Protein ID: WP_126445976.1
Type: Toxin
Protein ID: WP_126445976.1
Location: 1729945..1730175 (231 bp)
Type: Antitoxin
Protein ID: WP_126445978.1
Type: Antitoxin
Protein ID: WP_126445978.1
Location: 1731290..1732147 (858 bp)
Type: Others
Protein ID: WP_126445982.1
Type: Others
Protein ID: WP_126445982.1
Location: 1732147..1732500 (354 bp)
Type: Others
Protein ID: WP_126445984.1
Type: Others
Protein ID: WP_126445984.1
Location: 1732497..1733609 (1113 bp)
Type: Others
Protein ID: WP_126445986.1
Type: Others
Protein ID: WP_126445986.1
Loading, please wait
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EL335_RS08595 | 1726747..1727682 | - | 936 | WP_126445972.1 | bifunctional riboflavin kinase/FAD synthetase | - |
| EL335_RS08600 | 1727715..1728911 | - | 1197 | WP_284155499.1 | N-acetylmuramoyl-L-alanine amidase | - |
| EL335_RS08605 | 1728923..1729624 | - | 702 | WP_284155300.1 | tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE | - |
| EL335_RS08610 | 1729617..1729955 | - | 339 | WP_126445976.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin |
| EL335_RS08615 | 1729945..1730175 | - | 231 | WP_126445978.1 | type II toxin-antitoxin system PrlF family antitoxin | Antitoxin |
| EL335_RS08620 | 1730265..1731302 | + | 1038 | WP_126445980.1 | tRNA epoxyqueuosine(34) reductase QueG | - |
| EL335_RS08625 | 1731290..1732147 | - | 858 | WP_126445982.1 | sulfurtransferase | - |
| EL335_RS08630 | 1732147..1732500 | - | 354 | WP_126445984.1 | STAS/SEC14 domain-containing protein | - |
| EL335_RS08635 | 1732497..1733609 | - | 1113 | WP_126445986.1 | aromatic ring-hydroxylating dioxygenase subunit alpha | - |
| EL335_RS08640 | 1733756..1733998 | + | 243 | WP_126445989.1 | exodeoxyribonuclease VII small subunit | - |
| EL335_RS08645 | 1733995..1734882 | + | 888 | WP_126445991.1 | polyprenyl synthetase family protein | - |
Associated MGEs
Loading, please wait
MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 113 a.a. Molecular weight: 12212.21 Da Isoelectric Point: 8.8072
>T31983 WP_126445976.1 NZ_AP018718:c1729955-1729617 [Sulfuricystis multivorans]
VTFDRFAVVRVPFPFTDRCAVKNRPALVLSSAERFNAPTGHAVMAMITSAANAPWALDCPIEDLSAAGLPAPSKVRFKLF
TLDCRLVRGELGKLSNEDIERVRTRLEALLGG
VTFDRFAVVRVPFPFTDRCAVKNRPALVLSSAERFNAPTGHAVMAMITSAANAPWALDCPIEDLSAAGLPAPSKVRFKLF
TLDCRLVRGELGKLSNEDIERVRTRLEALLGG
Download Length: 339 bp
>T31983 NZ_AP018718:c1729955-1729617 [Sulfuricystis multivorans]
GTGACCTTTGATCGCTTCGCGGTCGTGCGGGTGCCGTTTCCGTTTACCGACCGCTGCGCAGTGAAGAACCGGCCTGCCTT
GGTGCTTTCGTCGGCCGAACGGTTCAATGCTCCGACGGGTCATGCAGTGATGGCGATGATTACCTCTGCGGCCAATGCGC
CGTGGGCGCTCGATTGCCCGATCGAAGATCTTTCTGCCGCCGGCTTGCCGGCCCCATCCAAAGTGCGTTTCAAGCTTTTT
ACCCTCGATTGCCGACTGGTGCGCGGGGAGCTTGGCAAACTCTCGAACGAAGACATCGAGCGCGTGCGAACACGGTTGGA
GGCGCTGCTGGGTGGCTGA
GTGACCTTTGATCGCTTCGCGGTCGTGCGGGTGCCGTTTCCGTTTACCGACCGCTGCGCAGTGAAGAACCGGCCTGCCTT
GGTGCTTTCGTCGGCCGAACGGTTCAATGCTCCGACGGGTCATGCAGTGATGGCGATGATTACCTCTGCGGCCAATGCGC
CGTGGGCGCTCGATTGCCCGATCGAAGATCTTTCTGCCGCCGGCTTGCCGGCCCCATCCAAAGTGCGTTTCAAGCTTTTT
ACCCTCGATTGCCGACTGGTGCGCGGGGAGCTTGGCAAACTCTCGAACGAAGACATCGAGCGCGTGCGAACACGGTTGGA
GGCGCTGCTGGGTGGCTGA
Antitoxin
Download Length: 77 a.a. Molecular weight: 8191.26 Da Isoelectric Point: 4.3297
>AT31983 WP_126445978.1 NZ_AP018718:c1730175-1729945 [Sulfuricystis multivorans]
MLAIAKITAKGQTTIPHEVRAALQVAPGDLIAWEIGADGTATVRRVQPLDLDYLRAIEGTLSEWAGSADEEAYRDL
MLAIAKITAKGQTTIPHEVRAALQVAPGDLIAWEIGADGTATVRRVQPLDLDYLRAIEGTLSEWAGSADEEAYRDL
Download Length: 231 bp
>AT31983 NZ_AP018718:c1730175-1729945 [Sulfuricystis multivorans]
ATGCTTGCCATCGCCAAGATCACCGCCAAGGGACAAACCACCATTCCACACGAGGTGCGCGCCGCGCTACAGGTCGCACC
AGGCGATTTGATCGCTTGGGAAATCGGCGCCGACGGAACGGCGACGGTACGCCGCGTGCAACCGCTCGATCTCGATTATC
TGCGTGCGATTGAGGGCACGCTTTCCGAATGGGCCGGCAGCGCCGATGAGGAAGCCTATCGTGACCTTTGA
ATGCTTGCCATCGCCAAGATCACCGCCAAGGGACAAACCACCATTCCACACGAGGTGCGCGCCGCGCTACAGGTCGCACC
AGGCGATTTGATCGCTTGGGAAATCGGCGCCGACGGAACGGCGACGGTACGCCGCGTGCAACCGCTCGATCTCGATTATC
TGCGTGCGATTGAGGGCACGCTTTCCGAATGGGCCGGCAGCGCCGATGAGGAAGCCTATCGTGACCTTTGA