Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 777917..778419 Replicon chromosome
Accession NZ_AP018718
Organism Sulfuricystis multivorans strain J5B

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag EL335_RS03855 Protein ID WP_126444329.1
Coordinates 778165..778419 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EL335_RS03850 Protein ID WP_126444328.1
Coordinates 777917..778168 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL335_RS03830 773128..773760 - 633 WP_126444324.1 TetR/AcrR family transcriptional regulator -
EL335_RS03835 773855..774466 + 612 WP_126444325.1 hypothetical protein -
EL335_RS03840 774492..775763 - 1272 WP_126444326.1 NnrS family protein -
EL335_RS03845 775760..777622 - 1863 WP_126444327.1 nitric oxide reductase -
EL335_RS03850 777917..778168 + 252 WP_126444328.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
EL335_RS03855 778165..778419 + 255 WP_126444329.1 Txe/YoeB family addiction module toxin Toxin
EL335_RS03860 778683..779078 - 396 WP_126444330.1 hypothetical protein -
EL335_RS03865 779075..779857 - 783 WP_284155438.1 CbbQ/NirQ/NorQ/GpvN family protein -
EL335_RS03870 780145..780432 - 288 WP_126444332.1 cytochrome C oxidase subunit IV family protein -
EL335_RS03875 780429..781028 - 600 WP_284155439.1 cytochrome c oxidase subunit 3 family protein -
EL335_RS03880 781025..781741 - 717 WP_126444333.1 c-type cytochrome -
EL335_RS03885 781746..782948 - 1203 WP_172600022.1 nitrous oxide reductase family maturation protein NosD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10200.71 Da        Isoelectric Point: 9.4385

>T31982 WP_126444329.1 NZ_AP018718:778165-778419 [Sulfuricystis multivorans]
VKLVFADEAWEDYLYWQKQDKKMVERINKLIREIQREPFGGVGKPEPLKHALSGFWSRRITDEHRIVYRVEGDQLQIAQL
RFHY

Download         Length: 255 bp

>T31982 NZ_AP018718:778165-778419 [Sulfuricystis multivorans]
GTGAAGCTGGTCTTCGCAGACGAGGCATGGGAAGACTACCTGTATTGGCAAAAGCAGGATAAAAAAATGGTCGAGCGGAT
CAACAAACTGATTCGCGAGATCCAGCGAGAACCATTCGGCGGCGTCGGAAAACCCGAACCGCTGAAACACGCACTCTCGG
GATTTTGGTCACGCCGGATCACAGACGAGCACCGAATAGTGTATCGGGTTGAAGGCGACCAACTTCAAATAGCCCAATTG
CGTTTCCATTACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9150.56 Da        Isoelectric Point: 6.9767

>AT31982 WP_126444328.1 NZ_AP018718:777917-778168 [Sulfuricystis multivorans]
MDAITYTTLRANLASAMDRVCDDHEALIITRNGEQSVVMLSLEDYKALEETAYLLRTPANAKRLLTAVAQLNAGKGIERK
LAK

Download         Length: 252 bp

>AT31982 NZ_AP018718:777917-778168 [Sulfuricystis multivorans]
ATGGATGCGATTACCTACACGACGCTTCGCGCGAATTTGGCGAGCGCGATGGATCGAGTCTGCGACGACCACGAAGCCTT
GATTATCACCCGCAACGGAGAGCAGTCGGTTGTGATGCTCTCGCTTGAAGACTATAAGGCGTTGGAAGAAACCGCCTATC
TCTTGCGCACACCCGCGAACGCGAAGCGTCTTCTCACGGCGGTAGCGCAATTGAATGCCGGCAAGGGCATCGAGCGGAAA
CTGGCCAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References