Detailed information of TA system TA031977

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-yefM/YoeB-RelB
• Location: 362902..363418
• Replicon: chromosome
• Accession: NZ_AP018689
• Organism: Vibrio aphrogenes strain CA-1004

Toxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: VCA1004_RS01765
• Protein ID: WP_164520809.1
• Coordinates: 363149..363418 (+)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: VCA1004_RS01760
• Protein ID: WP_086982138.1
• Coordinates: 362902..363156 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
VCA1004_RS01750	359682..360446	+	765	WP_086982136.1	DeoR family transcriptional regulator	-
VCA1004_RS01755	360567..362399	+	1833	WP_086982137.1	glutamine--fructose-6-phosphate transaminase (isomerizing)	-
VCA1004_RS01760	362902..363156	+	255	WP_086982138.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
VCA1004_RS01765	363149..363418	+	270	WP_164520809.1	Txe/YoeB family addiction module toxin	Toxin
VCA1004_RS01770	363615..365336	-	1722	WP_086982140.1	glycosyltransferase family 39 protein	-
VCA1004_RS01775	365323..366015	-	693	WP_086982141.1	VTT domain-containing protein	-
VCA1004_RS01780	366019..366768	-	750	WP_086982142.1	glycosyltransferase family 2 protein	-
VCA1004_RS01785	367058..367489	-	432	WP_086982143.1	Zn(2+)-responsive transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (10-89)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 10685.05 Da
• Isoelectric Point: 7.9817

>T31977 WP_164520809.1 NZ_AP018689:363149-363418 [Vibrio aphrogenes]
MSSRQRLLSWTDDAWDDYLYWQTQDKKTLKRINKIINDVKRSPFEGIGKPEPLKENLSGFWSRRIDDTNRLVYAVDDEAI
TIISCRYHY

Nucleotide

• Length: 270 bp

>T31977 NZ_AP018689:363149-363418 [Vibrio aphrogenes]
ATGAGTAGTCGTCAACGTCTATTGTCGTGGACTGATGACGCTTGGGATGACTACTTGTATTGGCAAACCCAAGACAAGAA
AACACTAAAGCGCATCAACAAAATTATCAATGATGTTAAGCGCTCTCCTTTTGAGGGCATCGGTAAACCTGAACCGTTAA
AAGAGAACTTATCTGGTTTTTGGTCTCGCCGTATTGATGATACTAATAGGCTTGTTTATGCGGTCGATGATGAAGCGATA
ACGATAATTTCGTGTCGTTACCACTACTAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9469.65 Da
• Isoelectric Point: 5.6785

>AT31977 WP_086982138.1 NZ_AP018689:362902-363156 [Vibrio aphrogenes]
MRIVSFTEARNSLKAVLDGVVNDADTTVITRRDSEDAVVMSLDYYNSLMETVHLLRSPKNAEHLNRSVAQYRAGKTTARE
LIDE

Nucleotide

• Length: 255 bp

>AT31977 NZ_AP018689:362902-363156 [Vibrio aphrogenes]
ATGAGAATCGTATCTTTTACTGAAGCTAGAAATAGTCTTAAAGCTGTTTTAGACGGTGTAGTTAATGATGCTGATACAAC
AGTCATTACACGCCGTGATTCTGAAGATGCAGTGGTGATGTCTTTAGACTACTACAACAGCCTTATGGAGACAGTTCACT
TACTGCGCTCCCCTAAAAATGCTGAACACCTAAACCGTTCGGTAGCACAGTATCGTGCAGGTAAAACAACAGCACGAGAG
TTAATTGATGAGTAG