Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 23575..24115 Replicon plasmid 2
Accession NZ_AP018688
Organism Vibrio rumoiensis strain FERM P-14531

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag VRUMOI_RS18820 Protein ID WP_027695183.1
Coordinates 23819..24115 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag VRUMOI_RS18815 Protein ID WP_027695182.1
Coordinates 23575..23832 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VRUMOI_RS18800 19790..19996 + 207 WP_089138980.1 peptidoglycan-binding protein -
VRUMOI_RS18805 20037..20846 - 810 WP_162598466.1 RsiV family protein -
VRUMOI_RS18810 22121..23182 + 1062 WP_089138977.1 tyrosine-type recombinase/integrase -
VRUMOI_RS18815 23575..23832 + 258 WP_027695182.1 antitoxin Antitoxin
VRUMOI_RS18820 23819..24115 + 297 WP_027695183.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
VRUMOI_RS18825 24586..25755 - 1170 WP_162598467.1 group II intron reverse transcriptase/maturase -
VRUMOI_RS18830 26117..26725 + 609 WP_040223437.1 recombinase family protein -
VRUMOI_RS18835 26722..26907 - 186 WP_024562121.1 ribbon-helix-helix domain-containing protein -
VRUMOI_RS18840 27384..28388 - 1005 WP_000427614.1 IS110-like element IS5075 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..109617 109617
- flank IS/Tn - - 27384..28388 1004


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-85)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11376.69 Da        Isoelectric Point: 10.6637

>T31976 WP_027695183.1 NZ_AP018688:23819-24115 [Vibrio rumoiensis]
MTVYKLKFERKAQKLFSKLGEPVKSQFKEKLKKIQVNPHIEANKLHGGLSGCYKIKLKQSGYRLVYKVVDDELIVLILAV
GKREKKEAYLMAQRLLNK

Download         Length: 297 bp

>T31976 NZ_AP018688:23819-24115 [Vibrio rumoiensis]
TTGACAGTTTATAAGTTGAAATTTGAACGAAAAGCCCAAAAACTTTTCTCTAAATTAGGAGAGCCGGTTAAATCTCAGTT
CAAAGAAAAACTCAAAAAGATTCAAGTTAATCCGCACATAGAGGCAAACAAATTACATGGTGGATTATCGGGATGTTACA
AAATCAAACTCAAGCAATCTGGTTATCGACTGGTTTATAAAGTTGTTGATGATGAATTAATCGTGCTTATCTTAGCCGTC
GGAAAACGAGAAAAAAAAGAAGCCTATTTAATGGCTCAAAGACTGTTAAATAAATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9354.66 Da        Isoelectric Point: 3.9554

>AT31976 WP_027695182.1 NZ_AP018688:23575-23832 [Vibrio rumoiensis]
MNLTNNILTDVSAGLTQLKNNPMGVLEEGHGAPVAILNRNKPAFYAVPAALYEKMVDELENIELMKMAQEAYETGEFVEV
DLDSL

Download         Length: 258 bp

>AT31976 NZ_AP018688:23575-23832 [Vibrio rumoiensis]
ATGAACTTAACAAACAACATTTTGACGGATGTGAGTGCTGGACTTACTCAGCTCAAAAATAATCCAATGGGCGTATTAGA
AGAAGGCCATGGTGCGCCTGTTGCTATTTTAAATCGCAACAAACCTGCATTTTACGCTGTCCCAGCCGCTTTATATGAAA
AAATGGTTGATGAGCTTGAAAATATTGAGCTAATGAAAATGGCTCAAGAAGCTTATGAAACGGGTGAGTTTGTTGAGGTA
GACCTTGACAGTTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References